{"id":5210,"date":"2021-02-26T21:17:29","date_gmt":"2021-02-27T05:17:29","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=5210"},"modified":"2021-02-26T21:17:29","modified_gmt":"2021-02-27T05:17:29","slug":"dexamethasone-in-hospitalized-patients-with-covid-19-preliminary-report","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/26\/dexamethasone-in-hospitalized-patients-with-covid-19-preliminary-report\/","title":{"rendered":"Dexamethasone in Hospitalized Patients with Covid-19 \u2014 Preliminary Report"},"content":{"rendered":"<ul>\n<li>In patients hospitalized with COVID-19, the administration of 6 mg\/day for ten days of the steroid dexamethasone resulted in statistically significantly lower 28-day mortality among those who were receiving either invasive mechanical ventilation (29% vs. 41%) or oxygen alone (23% vs. 26%) at randomization but not among those receiving no respiratory support (18% vs. 14%). Patients in the dexamethasone group also had a shorter duration of hospitalization than those in the usual care group (median, 12 days vs. 13 days). <i>[EDITORIAL NOTE: An earlier analysis of this RECOVERY trial was summarized as a pre-print on July 20, 2020.]<\/i><\/li>\n<\/ul>\n<p><i>Horby et al. (July 17, 2020). Dexamethasone in Hospitalized Patients with Covid-19 \u2014 Preliminary Report. New England Journal of Medicine. <\/i><a href=\"https:\/\/doi.org\/10.1056\/NEJMoa2021436\">https:\/\/doi.org\/10.1056\/NEJMoa2021436<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In patients hospitalized with COVID-19, the administration of 6 mg\/day for ten days of the steroid dexamethasone resulted in statistically significantly lower 28-day mortality among those who were receiving either invasive mechanical ventilation (29% vs. 41%) or oxygen alone (23% vs. 26%) at randomization but not among those receiving no respiratory support (18% vs. 14%)&#8230;.<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/26\/dexamethasone-in-hospitalized-patients-with-covid-19-preliminary-report\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[28],"topic":[19],"class_list":["post-5210","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-treatment","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5210","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=5210"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5210\/revisions"}],"predecessor-version":[{"id":5211,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5210\/revisions\/5211"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=5210"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=5210"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=5210"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=5210"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}