{"id":5222,"date":"2021-02-26T21:22:37","date_gmt":"2021-02-27T05:22:37","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=5222"},"modified":"2021-02-26T21:22:37","modified_gmt":"2021-02-27T05:22:37","slug":"obesity-may-hamper-sars-cov-2-vaccine-immunogenicity","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/26\/obesity-may-hamper-sars-cov-2-vaccine-immunogenicity\/","title":{"rendered":"Obesity May Hamper SARS-CoV-2 Vaccine Immunogenicity"},"content":{"rendered":"<ul>\n<li><i>[pre-print; not peer-reviewed]<\/i> Antibody titers two weeks after receiving a second dose of the Pfizer-BioNTech vaccine were lower in obese healthcare workers (BMI &gt;30), after adjusting for age. 99.5% of the 248 participants developed a humoral immune response after vaccination, and antibody titers were higher in younger people and in women. The authors note that the importance of the magnitude of a humoral response is still under investigation.<span class=\"Apple-converted-space\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i>Pellini et al. (Feb 26, 2021). Obesity May Hamper SARS-CoV-2 Vaccine Immunogenicity. Pre-print downloaded Feb 26 from <\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.02.24.21251664\">https:\/\/doi.org\/10.1101\/2021.02.24.21251664<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[pre-print; not peer-reviewed] Antibody titers two weeks after receiving a second dose of the Pfizer-BioNTech vaccine were lower in obese healthcare workers (BMI &gt;30), after adjusting for age. 99.5% of the 248 participants developed a humoral immune response after vaccination, and antibody titers were higher in younger people and in women. The authors note that&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/02\/26\/obesity-may-hamper-sars-cov-2-vaccine-immunogenicity\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[34,187],"topic":[31],"class_list":["post-5222","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-clinical-characteristics","tag-vaccinations","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5222","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=5222"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5222\/revisions"}],"predecessor-version":[{"id":5223,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5222\/revisions\/5223"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=5222"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=5222"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=5222"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=5222"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}