{"id":535,"date":"2020-08-26T19:48:10","date_gmt":"2020-08-27T02:48:10","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=535"},"modified":"2020-08-31T19:49:09","modified_gmt":"2020-09-01T02:49:09","slug":"an-inflammatory-cytokine-signature-predicts-covid-19-severity-and-survival","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/26\/an-inflammatory-cytokine-signature-predicts-covid-19-severity-and-survival\/","title":{"rendered":"An Inflammatory Cytokine Signature Predicts COVID-19 Severity and Survival"},"content":{"rendered":"<ul>\n<li>Measurement of inflammatory markers among hospitalized COVID-19 patients (n=1,484) found that high serum IL-6, IL-8, and TNF-\u03b1 levels at the time of hospitalization were strong and independent predictors of patient survival. IL-6 and TNF-\u03b1 serum levels remained significant predictors of disease severity and death after adjustment for disease severity, common laboratory inflammation markers, hypoxia and other vital signs, demographics, and a range of comorbidities.<\/li>\n<\/ul>\n<p><em>Del Valle et al. (Aug 24, 2020). An Inflammatory Cytokine Signature Predicts COVID-19 Severity and Survival. Nature Medicine. <a href=\"https:\/\/doi.org\/10.1038\/s41591-020-1051-9\">https:\/\/doi.org\/10.1038\/s41591-020-1051-9<\/a><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Measurement of inflammatory markers among hospitalized COVID-19 patients (n=1,484) found that high serum IL-6, IL-8, and TNF-\u03b1 levels at the time of hospitalization were strong and independent predictors of patient survival. IL-6 and TNF-\u03b1 serum levels remained significant predictors of disease severity and death after adjustment for disease severity, common laboratory inflammation markers, hypoxia and&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/26\/an-inflammatory-cytokine-signature-predicts-covid-19-severity-and-survival\/\">Read more<\/a><\/div>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[34],"topic":[20],"class_list":["post-535","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-clinical-characteristics","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/535","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=535"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/535\/revisions"}],"predecessor-version":[{"id":536,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/535\/revisions\/536"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=535"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=535"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=535"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=535"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}