{"id":5551,"date":"2021-03-02T23:18:59","date_gmt":"2021-03-03T07:18:59","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=5551"},"modified":"2021-03-02T23:18:59","modified_gmt":"2021-03-03T07:18:59","slug":"long-term-sars-cov-2-specific-immune-and-inflammatory-responses-across-a-clinically-diverse-cohort-of-individuals-recovering-from-covid-19","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/02\/long-term-sars-cov-2-specific-immune-and-inflammatory-responses-across-a-clinically-diverse-cohort-of-individuals-recovering-from-covid-19\/","title":{"rendered":"Long-Term SARS-CoV-2-Specific Immune and Inflammatory Responses Across a Clinically Diverse Cohort of Individuals Recovering from COVID-19"},"content":{"rendered":"<ul>\n<li><i>[Pre-print, not peer-reviewed]<\/i> A longitudinal study in California found that SARS-CoV-2-specific T cell responses remained largely stable up to 9 months following SARS-CoV-2 infection (n=70). Stronger CD4+ T cell responses were associated with initial disease severity as well as neutralizing antibody levels, whereas pre-existing lung disease predicted long-term CD8+ T cell responses. While 36% of participants had COVID-19-related symptoms persisting approximately 4 months after initial illness (median 125 days), no substantial differences in long-term T cell or antibody responses were identified between participants with or without persisting symptoms.<\/li>\n<\/ul>\n<p><i>Peluso et al.\u00a0(Mar 1, 2021). Long-Term SARS-CoV-2-Specific Immune and Inflammatory Responses Across a Clinically Diverse Cohort of Individuals Recovering from COVID-19. Pre-print downloaded Mar 2 from <\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.02.26.21252308\">https:\/\/doi.org\/10.1101\/2021.02.26.21252308<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] A longitudinal study in California found that SARS-CoV-2-specific T cell responses remained largely stable up to 9 months following SARS-CoV-2 infection (n=70). Stronger CD4+ T cell responses were associated with initial disease severity as well as neutralizing antibody levels, whereas pre-existing lung disease predicted long-term CD8+ T cell responses. While 36% of&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/02\/long-term-sars-cov-2-specific-immune-and-inflammatory-responses-across-a-clinically-diverse-cohort-of-individuals-recovering-from-covid-19\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32,51],"topic":[31],"class_list":["post-5551","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","tag-sequelae","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5551","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=5551"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5551\/revisions"}],"predecessor-version":[{"id":5552,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5551\/revisions\/5552"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=5551"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=5551"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=5551"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=5551"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}