{"id":5553,"date":"2021-03-02T23:20:14","date_gmt":"2021-03-03T07:20:14","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=5553"},"modified":"2021-03-02T23:20:14","modified_gmt":"2021-03-03T07:20:14","slug":"binding-and-neutralization-antibody-titers-after-a-single-vaccine-dose-in-health-care-workers-previously-infected-with-sars-cov-2","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/02\/binding-and-neutralization-antibody-titers-after-a-single-vaccine-dose-in-health-care-workers-previously-infected-with-sars-cov-2\/","title":{"rendered":"Binding and Neutralization Antibody Titers After a Single Vaccine Dose in Health Care Workers Previously Infected With SARS-CoV-2"},"content":{"rendered":"<ul>\n<li>A single dose of mRNA vaccine (Pfizer or Moderna vaccine) elicited higher antibody and neutralization titers in health care workers (n=59) with previous serology-confirmed SARS-CoV-2 infection compared to healthcare workers who were seronegative at baseline. At 14 days post-vaccination, antibody binding strength to SARS-CoV-2 antigens from participants with both asymptomatic and symptomatic prior infection were up to 38-fold higher compared to those seronegative at baseline. Similarly, neutralizing titers were several orders of magnitude higher among those with prior infection when compared to seronegative participants.<\/li>\n<\/ul>\n<p><i>Saadat et al.\u00a0(Mar 1, 2021). Binding and Neutralization Antibody Titers After a Single Vaccine Dose in Health Care Workers Previously Infected With SARS-CoV-2. JAMA. <\/i><a href=\"https:\/\/doi.org\/10.1001\/jama.2021.3341\">https:\/\/doi.org\/10.1001\/jama.2021.3341<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A single dose of mRNA vaccine (Pfizer or Moderna vaccine) elicited higher antibody and neutralization titers in health care workers (n=59) with previous serology-confirmed SARS-CoV-2 infection compared to healthcare workers who were seronegative at baseline. At 14 days post-vaccination, antibody binding strength to SARS-CoV-2 antigens from participants with both asymptomatic and symptomatic prior infection were&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/02\/binding-and-neutralization-antibody-titers-after-a-single-vaccine-dose-in-health-care-workers-previously-infected-with-sars-cov-2\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[67,147],"topic":[31],"class_list":["post-5553","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-antibodies","tag-vaccination","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5553","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=5553"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5553\/revisions"}],"predecessor-version":[{"id":5554,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5553\/revisions\/5554"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=5553"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=5553"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=5553"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=5553"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}