{"id":5853,"date":"2020-04-10T14:17:43","date_gmt":"2020-04-10T21:17:43","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=5853"},"modified":"2021-03-05T14:18:47","modified_gmt":"2021-03-05T22:18:47","slug":"variation-in-false-negative-rate-of-rt-pcr-based-sars-cov-2-tests-by-time-since-exposure","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/04\/10\/variation-in-false-negative-rate-of-rt-pcr-based-sars-cov-2-tests-by-time-since-exposure\/","title":{"rendered":"Variation in False Negative Rate of RT-PCR Based SARS-CoV-2 Tests by Time Since Exposure"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">The authors used previously published data on RT-PCR sensitivity of samples derived from nasal swabs to calculate the false negative rate by day since exposure and symptom onset.\u00a0\u00a0<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">The probability of a false negative test ranged from 100% on day one post exposure to 26% three days after onset symptoms.\u00a0 The authors conclude that in cases of high clinical suspicion, patients should not be ruled out on the bases of RT-PCR alone.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Kucirka et al. (Apr 10, 2020). Variation in False Negative Rate of RT-PCR Based SARS-CoV-2 Tests by Time Since Exposure.\u00a0 Pre-print downloaded Apr 10 from<\/span><\/i> <a href=\"https:\/\/doi.org\/10.1101\/2020.04.07.20051474\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2020.04.07.20051474<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The authors used previously published data on RT-PCR sensitivity of samples derived from nasal swabs to calculate the false negative rate by day since exposure and symptom onset.\u00a0\u00a0 The probability of a false negative test ranged from 100% on day one post exposure to 26% three days after onset symptoms.\u00a0 The authors conclude that in&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/04\/10\/variation-in-false-negative-rate-of-rt-pcr-based-sars-cov-2-tests-by-time-since-exposure\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_members_access_role":[],"_members_access_error":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-5853","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5853","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=5853"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5853\/revisions"}],"predecessor-version":[{"id":5854,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5853\/revisions\/5854"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=5853"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=5853"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=5853"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=5853"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}