{"id":587,"date":"2020-08-28T09:23:25","date_gmt":"2020-08-28T16:23:25","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=587"},"modified":"2020-09-03T09:24:25","modified_gmt":"2020-09-03T16:24:25","slug":"clinical-characteristics-of-children-and-young-people-admitted-to-hospital-with-covid-19-in-united-kingdom-prospective-multicentre-observational-cohort-study","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/28\/clinical-characteristics-of-children-and-young-people-admitted-to-hospital-with-covid-19-in-united-kingdom-prospective-multicentre-observational-cohort-study\/","title":{"rendered":"Clinical Characteristics of Children and Young People Admitted to Hospital with Covid-19 in United Kingdom: Prospective Multicentre Observational Cohort Study"},"content":{"rendered":"<ul>\n<li>A prospective observational cohort study in the UK of children and young adults (n=651, median age=4.6, IQR 0.3-13.7) found that 52\/456 (11%) participants met the WHO case definition for multisystem inflammatory syndrome in children and adolescents temporally related to COVID-19 (MIS-C). Children who met criteria for MIS-C were older than children who did not (median 10.7 years vs 1.6 years) and were more likely to be of non-white ethnicity (64% vs 42%). The most common symptom clusters among the whole cohort were a respiratory illness followed by a systemic mucocutaneous enteric illness cluster that included headache, muscle ache, sore throat, vomiting, abdominal pain, rash, swollen lymph nodes and conjunctivitis. In multivariable analysis, acute COVID-19 was associated with age &lt;1 month (OR: 3.2, 95% CI 1.4-7.7), age 10-14 years (OR: 3.2, 95% CI: 1.6-7.0), and Black ethnicity (OR: 2.8, 1.4 to 5.6).<\/li>\n<\/ul>\n<p><em>Swann et al. (Aug 27, 2020). Clinical Characteristics of Children and Young People Admitted to Hospital with Covid-19 in United Kingdom: Prospective Multicentre Observational Cohort Study. BMJ. <a href=\"https:\/\/doi.org\/10.1136\/bmj.m3249\">https:\/\/doi.org\/10.1136\/bmj.m3249<\/a><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A prospective observational cohort study in the UK of children and young adults (n=651, median age=4.6, IQR 0.3-13.7) found that 52\/456 (11%) participants met the WHO case definition for multisystem inflammatory syndrome in children and adolescents temporally related to COVID-19 (MIS-C). Children who met criteria for MIS-C were older than children who did not (median&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/28\/clinical-characteristics-of-children-and-young-people-admitted-to-hospital-with-covid-19-in-united-kingdom-prospective-multicentre-observational-cohort-study\/\">Read more<\/a><\/div>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[34],"topic":[20],"class_list":["post-587","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-clinical-characteristics","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/587","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=587"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/587\/revisions"}],"predecessor-version":[{"id":588,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/587\/revisions\/588"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=587"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=587"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=587"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=587"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}