{"id":5918,"date":"2020-04-14T15:01:55","date_gmt":"2020-04-14T22:01:55","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=5918"},"modified":"2021-03-05T15:02:44","modified_gmt":"2021-03-05T23:02:44","slug":"no-evidence-of-clinical-efficacy-of-hydroxychloroquine-in-patients-hospitalised-for-covid-19-infection-and-requiring-oxygen-results-of-a-study-using-routinely-collected-data-to-emulate-a-target-trial","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/04\/14\/no-evidence-of-clinical-efficacy-of-hydroxychloroquine-in-patients-hospitalised-for-covid-19-infection-and-requiring-oxygen-results-of-a-study-using-routinely-collected-data-to-emulate-a-target-trial\/","title":{"rendered":"No evidence of clinical efficacy of hydroxychloroquine in patients hospitalised for COVID-19 infection and requiring oxygen: results of a study using routinely collected data to emulate a target trial"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">All adults in 4 French hospitals (n=181) with documented SARS-CoV-2 pneumonia were used to emulate a target trial assessing the effectiveness of hydroxychloroquine (HCQ) at 600 mg\/day. Findings do not support use of HQC, with no observed reduction in disease severity or death.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Mahevas et al.\u00a0 (April 14, 2020). No evidence of clinical efficacy of hydroxychloroquine in patients hospitalised for COVID-19 infection and requiring oxygen: results of a study using routinely collected data to emulate a target trial. Pre-print downloaded Apr 14 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.04.10.20060699\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2020.04.10.20060699<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>All adults in 4 French hospitals (n=181) with documented SARS-CoV-2 pneumonia were used to emulate a target trial assessing the effectiveness of hydroxychloroquine (HCQ) at 600 mg\/day. Findings do not support use of HQC, with no observed reduction in disease severity or death. Mahevas et al.\u00a0 (April 14, 2020). No evidence of clinical efficacy of&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/04\/14\/no-evidence-of-clinical-efficacy-of-hydroxychloroquine-in-patients-hospitalised-for-covid-19-infection-and-requiring-oxygen-results-of-a-study-using-routinely-collected-data-to-emulate-a-target-trial\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-5918","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5918","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=5918"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5918\/revisions"}],"predecessor-version":[{"id":5919,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/5918\/revisions\/5919"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=5918"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=5918"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=5918"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=5918"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}