{"id":6340,"date":"2020-04-28T14:30:34","date_gmt":"2020-04-28T21:30:34","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6340"},"modified":"2021-03-10T14:31:27","modified_gmt":"2021-03-10T22:31:27","slug":"the-effect-of-angiotensin-converting-enzyme-inhibitors-and-angiotensin-receptor-blockers-on-death-and-severity-of-disease-in-patients-with-coronavirus-disease-2019-covid-19-a-meta-analysis","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/04\/28\/the-effect-of-angiotensin-converting-enzyme-inhibitors-and-angiotensin-receptor-blockers-on-death-and-severity-of-disease-in-patients-with-coronavirus-disease-2019-covid-19-a-meta-analysis\/","title":{"rendered":"The effect of angiotensin converting enzyme inhibitors and angiotensin receptor blockers on death and severity of disease in patients with coronavirus disease 2019 (COVID-19): A meta-analysis"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">This meta-analysis includes five studies totaling 308 patients either taking or not taking angiotensin converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB).\u00a0 Patients on ACEi\/ARB showed a 44% reduction in odds of developing severe disease and a 62% reduction in odds of death when compared to patients not on ACEi\/ARB.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">The authors conclude that it is safe to use ACEi\/ARB with COVID-19 patients, and that this data suggests these medications may reduce the risk of developing severe disease and death.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Ghosal et al. (April 28, 2020). The effect of angiotensin converting enzyme inhibitors and angiotensin receptor blockers on death and severity of disease in patients with coronavirus disease 2019 (COVID-19): A meta-analysis. Pre-print downloaded Apr 28 from<\/span><\/i> <a href=\"https:\/\/doi.org\/10.1101\/2020.04.23.20076661\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2020.04.23.20076661<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This meta-analysis includes five studies totaling 308 patients either taking or not taking angiotensin converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB).\u00a0 Patients on ACEi\/ARB showed a 44% reduction in odds of developing severe disease and a 62% reduction in odds of death when compared to patients not on ACEi\/ARB. The authors conclude that&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/04\/28\/the-effect-of-angiotensin-converting-enzyme-inhibitors-and-angiotensin-receptor-blockers-on-death-and-severity-of-disease-in-patients-with-coronavirus-disease-2019-covid-19-a-meta-analysis\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-6340","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6340","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6340"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6340\/revisions"}],"predecessor-version":[{"id":6341,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6340\/revisions\/6341"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6340"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6340"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6340"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6340"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}