{"id":6342,"date":"2020-04-28T14:31:38","date_gmt":"2020-04-28T21:31:38","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6342"},"modified":"2021-03-10T14:32:26","modified_gmt":"2021-03-10T22:32:26","slug":"long-period-dynamics-of-viral-load-and-antibodies-for-sars-cov-2-infection-an-observational-cohort-study","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/04\/28\/long-period-dynamics-of-viral-load-and-antibodies-for-sars-cov-2-infection-an-observational-cohort-study\/","title":{"rendered":"Long period dynamics of viral load and antibodies for SARS-CoV-2 infection: an observational cohort study"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">This retrospective observational case series of 33 patients with SARS-CoV-2 pneumonia reviewed analysis of throat swabs, sputum, stool, and blood samples to evaluate viral load, IgM, IgG, spike protein receptor binding domain (RBD), and nucleocapsid.<\/span><\/li>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Results suggest that viral RNA persists in sputum and stool samples for a long time, and that anti-RBD may serve as a protective antibody against SARS-CoV-2 that is related to viral persistence and is valuable for development of vaccines.\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Huang et al. (April 27, 2020). Long period dynamics of viral load and antibodies for SARS-CoV-2 infection: an observational cohort study. Pre-print downloaded Apr 27 from<\/span><\/i> <a href=\"https:\/\/doi.org\/10.1101\/2020.04.22.20071258\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2020.04.22.20071258<\/span><\/a><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This retrospective observational case series of 33 patients with SARS-CoV-2 pneumonia reviewed analysis of throat swabs, sputum, stool, and blood samples to evaluate viral load, IgM, IgG, spike protein receptor binding domain (RBD), and nucleocapsid. Results suggest that viral RNA persists in sputum and stool samples for a long time, and that anti-RBD may serve&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/04\/28\/long-period-dynamics-of-viral-load-and-antibodies-for-sars-cov-2-infection-an-observational-cohort-study\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-6342","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6342","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6342"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6342\/revisions"}],"predecessor-version":[{"id":6343,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6342\/revisions\/6343"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6342"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6342"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6342"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6342"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}