{"id":6435,"date":"2021-03-11T20:54:14","date_gmt":"2021-03-12T04:54:14","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6435"},"modified":"2021-03-11T20:54:14","modified_gmt":"2021-03-12T04:54:14","slug":"antibody-responses-in-seropositive-persons-after-a-single-dose-of-sars-cov-2-mrna-vaccine","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/11\/antibody-responses-in-seropositive-persons-after-a-single-dose-of-sars-cov-2-mrna-vaccine\/","title":{"rendered":"Antibody Responses in Seropositive Persons after a Single Dose of SARS-CoV-2 MRNA Vaccine"},"content":{"rendered":"<ul>\n<li>After a single dose of either the Pfizer-BioNTech or Modernan vaccine, US vaccinees with prior SARS-CoV-2 infection (n=43) had antibody titers 10-45 times as high as those of vaccinees without prior SARS-CoV-2 infection (n=67), according to interim results of a longitudinal study. While titers of those with prior infection did not increase after the second dose, median antibody titers were 6-fold higher than those without prior infection. No substantial difference was noted in the dynamics of antibody responses elicited by the Pfizer-BioNTech and Moderna vaccines after the first dose.<\/li>\n<li>In separate analyses within the larger longitudinal study, vaccine side effects after the first dose occurred more frequently among vaccinees with prior infection. <i>[EDITORIAL NOTE: A pre-print related to this manuscript was summarized on February 1, 2020]<\/i><\/li>\n<\/ul>\n<p><i>Krammer et al.\u00a0(Mar 10, 2021). Antibody Responses in Seropositive Persons after a Single Dose of SARS-CoV-2 MRNA Vaccine. New England Journal of Medicine. <\/i><a href=\"https:\/\/doi.org\/10.1056\/NEJMc2101667\">https:\/\/doi.org\/10.1056\/NEJMc2101667<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>After a single dose of either the Pfizer-BioNTech or Modernan vaccine, US vaccinees with prior SARS-CoV-2 infection (n=43) had antibody titers 10-45 times as high as those of vaccinees without prior SARS-CoV-2 infection (n=67), according to interim results of a longitudinal study. While titers of those with prior infection did not increase after the second&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/11\/antibody-responses-in-seropositive-persons-after-a-single-dose-of-sars-cov-2-mrna-vaccine\/\">Read more<\/a><\/div>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[142],"topic":[31],"class_list":["post-6435","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-vaccine","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6435","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6435"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6435\/revisions"}],"predecessor-version":[{"id":6436,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6435\/revisions\/6436"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6435"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6435"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6435"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6435"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}