{"id":6514,"date":"2020-05-01T15:47:56","date_gmt":"2020-05-01T22:47:56","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6514"},"modified":"2021-03-12T15:48:52","modified_gmt":"2021-03-12T23:48:52","slug":"high-frequency-of-sars-cov-2-rnaemia-and-association-with-severe-disease","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/01\/high-frequency-of-sars-cov-2-rnaemia-and-association-with-severe-disease\/","title":{"rendered":"High Frequency of SARS-CoV-2 RNAemia and Association with Severe Disease"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Detection of SARS-CoV-2 RNA in the blood is associated with poor clinical outcomes and increased mortality among COVID-19 patients. In this study, SARS-CoV-2 RNA was detected in 33% (28\/85) of patients, the majority of whom were hospitalized (22\/28). Detection of RNA occurred more frequently in individuals who required an ICU transfer (32% v 14%; p=0.05), mechanical ventilation (21% v 4%, p-value = 0.01) and 30-day all-cause mortality (14 % v 0%, p-value = 0.01). Levels of viral RNA in the nasopharynx were not associated with detected SARS-CoV-2 RNA.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Hogan et al. (May 1, 2020). High Frequency of SARS-CoV-2 RNAemia and Association with Severe Disease. Pre-print downloaded May 1 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.04.26.20080101\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2020.04.26.20080101<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Detection of SARS-CoV-2 RNA in the blood is associated with poor clinical outcomes and increased mortality among COVID-19 patients. In this study, SARS-CoV-2 RNA was detected in 33% (28\/85) of patients, the majority of whom were hospitalized (22\/28). Detection of RNA occurred more frequently in individuals who required an ICU transfer (32% v 14%; p=0.05),&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/01\/high-frequency-of-sars-cov-2-rnaemia-and-association-with-severe-disease\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-6514","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6514","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6514"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6514\/revisions"}],"predecessor-version":[{"id":6515,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6514\/revisions\/6515"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6514"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6514"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6514"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6514"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}