{"id":6584,"date":"2021-03-15T13:53:23","date_gmt":"2021-03-15T20:53:23","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6584"},"modified":"2021-03-16T13:54:21","modified_gmt":"2021-03-16T20:54:21","slug":"an-observational-cohort-study-on-the-incidence-of-sars-cov-2-infection-and-b-1-1-7-variant-infection-in-healthcare-workers-by-antibody-and-vaccination-status","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/15\/an-observational-cohort-study-on-the-incidence-of-sars-cov-2-infection-and-b-1-1-7-variant-infection-in-healthcare-workers-by-antibody-and-vaccination-status\/","title":{"rendered":"An Observational Cohort Study on the Incidence of SARS-CoV-2 Infection and B.1.1.7 Variant Infection in Healthcare Workers by Antibody and Vaccination Status"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">[Pre-print, not peer-reviewed]<\/span><\/i><span style=\"font-weight: 400\"> A longitudinal cohort study of healthcare workers (HCWs) in England showed that both natural infection and vaccination (two doses of Pfizer\/BioNTech or Oxford\/AstraZeneca vaccine) provided more than 85% protection against symptomatic and asymptomatic SARS-CoV-2 infection, including with the B.1.1.7 variant. <\/span><span style=\"font-weight: 400\">No HCWs who had received both doses had symptomatic infection, and incidence was 98% lower among seropositive HCWs (aIRR = 0.02). Two vaccine doses or seropositivity reduced the incidence of any PCR-positive result with or without symptoms by 90% and 85%, respectively. Single-dose vaccination was slightly less effective and reduced the incidence of symptomatic infection by 67% and any PCR-positive result by 64%.\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Lumley et al.\u00a0(Mar 12, 2021). An Observational Cohort Study on the Incidence of SARS-CoV-2 Infection and B.1.1.7 Variant Infection in Healthcare Workers by Antibody and Vaccination Status. Pre-print downloaded Mar 15 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.03.09.21253218\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2021.03.09.21253218<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] A longitudinal cohort study of healthcare workers (HCWs) in England showed that both natural infection and vaccination (two doses of Pfizer\/BioNTech or Oxford\/AstraZeneca vaccine) provided more than 85% protection against symptomatic and asymptomatic SARS-CoV-2 infection, including with the B.1.1.7 variant. No HCWs who had received both doses had symptomatic infection, and incidence&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/15\/an-observational-cohort-study-on-the-incidence-of-sars-cov-2-infection-and-b-1-1-7-variant-infection-in-healthcare-workers-by-antibody-and-vaccination-status\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32],"topic":[31],"class_list":["post-6584","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6584","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6584"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6584\/revisions"}],"predecessor-version":[{"id":6585,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6584\/revisions\/6585"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6584"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6584"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6584"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6584"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}