{"id":6605,"date":"2020-05-04T14:17:04","date_gmt":"2020-05-04T21:17:04","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6605"},"modified":"2021-03-16T14:18:39","modified_gmt":"2021-03-16T21:18:39","slug":"cardiovascular-disease-drug-therapy-and-mortality-in-covid-19","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/04\/cardiovascular-disease-drug-therapy-and-mortality-in-covid-19\/","title":{"rendered":"Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"38\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Using medical record<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">\u00a0from 169 hospitals in Asia, Europe, and North America,\u00a0<\/span><span data-contrast=\"auto\">from\u00a0<\/span><span data-contrast=\"auto\">8,910 COVID-19 patients with known discharge status, these authors found\u00a0<\/span><span data-contrast=\"auto\">the following factors\u00a0<\/span><span data-contrast=\"auto\">were<\/span><span data-contrast=\"auto\">\u00a0positive<\/span><span data-contrast=\"auto\">ly<\/span><span data-contrast=\"auto\">\u00a0association with risk of death (i.e., higher value of the factor<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">associated with higher risk of death): age\u00a0<\/span><span data-contrast=\"auto\">&gt;<\/span><span data-contrast=\"auto\">65 years, coronary artery disease, heart failure, cardiac arrhythmia, COPD, current smoking.\u00a0<\/span><span data-contrast=\"auto\">O<\/span><span data-contrast=\"auto\">dds\u00a0ratio\u00a0<\/span><span data-contrast=\"auto\">were\u00a0<\/span><span data-contrast=\"auto\">between 1.79 and 2.95 for all\u00a0<\/span><span data-contrast=\"auto\">factors<\/span><span data-contrast=\"auto\">. For use of ACE\u00a0inhibitors\u00a0the association was negative, and for angiotensin-receptor-blockers the association was positive but not significant.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"auto\">Mehra et al. (May 1<\/span><\/i><i><span data-contrast=\"auto\">,<\/span><\/i><i><span data-contrast=\"auto\">\u00a02020). Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19. The New England Journal of Medicine.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1056\/NEJMoa2007621\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1056\/NEJMoa2007621<\/span><\/i><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Using medical records\u00a0from 169 hospitals in Asia, Europe, and North America,\u00a0from\u00a08,910 COVID-19 patients with known discharge status, these authors found\u00a0the following factors\u00a0were\u00a0positively\u00a0association with risk of death (i.e., higher value of the factor\u00a0associated with higher risk of death): age\u00a0&gt;65 years, coronary artery disease, heart failure, cardiac arrhythmia, COPD, current smoking.\u00a0Odds\u00a0ratio\u00a0were\u00a0between 1.79 and 2.95 for all\u00a0factors. For&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/04\/cardiovascular-disease-drug-therapy-and-mortality-in-covid-19\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_members_access_role":[],"_members_access_error":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-6605","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6605","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6605"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6605\/revisions"}],"predecessor-version":[{"id":6606,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6605\/revisions\/6606"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6605"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6605"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6605"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6605"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}