{"id":6607,"date":"2020-05-04T14:18:50","date_gmt":"2020-05-04T21:18:50","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6607"},"modified":"2021-03-16T14:19:48","modified_gmt":"2021-03-16T21:19:48","slug":"risk-of-qt-interval-prolongation-associated-with-use-of-hydroxychloroquine-with-or-without-concomitant-azithromycin-among-hospitalized-patients-testing-positive-for-coronavirus-dis","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/04\/risk-of-qt-interval-prolongation-associated-with-use-of-hydroxychloroquine-with-or-without-concomitant-azithromycin-among-hospitalized-patients-testing-positive-for-coronavirus-dis\/","title":{"rendered":"Risk of QT Interval Prolongation Associated\u00a0With\u00a0Use of Hydroxychloroquine\u00a0With\u00a0or Without Concomitant Azithromycin Among Hospitalized Patients Testing Positive for Coronavirus Disease 2019 (COVID-19)"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"38\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Use of hydroxychloroquine\u00a0<\/span><span data-contrast=\"auto\">can increase the risk of corrected QT (QTc) prolongation, a type of cardiac arrhythmia.\u00a0<\/span><span data-contrast=\"auto\">Among 90 patients in an academic tertiary care center in Boston with at least one positive\u00a0<\/span><span data-contrast=\"auto\">test for SARS-CoV-2<\/span><span data-contrast=\"auto\">, QTc was significantly longer after initiation of hydroxychloroquine, and this effect stronger for patients receiving both hydroxychloroquine and azithromycin.\u00a0<\/span><span data-contrast=\"auto\">The authors recommend judicious use of hydroxychloroquine, along with monitoring of QTc and concomitant\u00a0<\/span><span data-contrast=\"auto\">medications<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"auto\">Mercuro et al. (May 1<\/span><\/i><i><span data-contrast=\"auto\">,<\/span><\/i><i><span data-contrast=\"auto\">\u00a02020). Risk of QT Interval Prolongation Associated\u00a0With\u00a0Use of Hydroxychloroquine\u00a0With\u00a0or Without Concomitant Azithromycin Among Hospitalized Patients Testing Positive for Coronavirus Disease 2019 (COVID-19). JAMA Cardiology.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jamacardio.2020.1834\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jamacardio.2020.1834<\/span><\/i><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Use of hydroxychloroquine\u00a0can increase the risk of corrected QT (QTc) prolongation, a type of cardiac arrhythmia.\u00a0Among 90 patients in an academic tertiary care center in Boston with at least one positive\u00a0test for SARS-CoV-2, QTc was significantly longer after initiation of hydroxychloroquine, and this effect stronger for patients receiving both hydroxychloroquine and azithromycin.\u00a0The authors recommend judicious&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/04\/risk-of-qt-interval-prolongation-associated-with-use-of-hydroxychloroquine-with-or-without-concomitant-azithromycin-among-hospitalized-patients-testing-positive-for-coronavirus-dis\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-6607","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6607","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6607"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6607\/revisions"}],"predecessor-version":[{"id":6608,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6607\/revisions\/6608"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6607"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6607"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6607"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6607"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}