{"id":6613,"date":"2020-05-04T14:22:21","date_gmt":"2020-05-04T21:22:21","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6613"},"modified":"2021-03-16T14:23:13","modified_gmt":"2021-03-16T21:23:13","slug":"early-detection-of-sars-cov-2-antibodies-in-covid-19-patients-as-a-serologic-marker-of-infection","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/04\/early-detection-of-sars-cov-2-antibodies-in-covid-19-patients-as-a-serologic-marker-of-infection\/","title":{"rendered":"Early Detection of SARS-CoV-2 Antibodies in COVID-19 Patients as a Serologic Marker of Infection"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"41\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Using CHO cell expressed full len<\/span><span data-contrast=\"auto\">gth<\/span><span data-contrast=\"auto\">\u00a0SARS-CoV-2 S1 protein as capturing antigen, Zhao et al. develop and validate a rapid COVID-19 serology ELISA kit able to detect SARS-CoV-2 antibody 1 day\u00a0<\/span><span data-contrast=\"auto\">after the onset of COVID-19. The reported specificity and sensitivity of the ELISA kit was 97.5% and 97.1%, respectively, with overall accuracy rate of 97.3%<\/span><span data-contrast=\"auto\">\u00a0(based on 412 negative and 69 positive samples)<\/span><span data-contrast=\"auto\">. Rapid serological tests such as these could<\/span><span data-contrast=\"auto\">\u00a0contribute to additional surveillance in hospitals and other frontline environments where there is a high volume of close contact with confirmed cases.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:360,&quot;335559739&quot;:160,&quot;335559740&quot;:259,&quot;469777462&quot;:[720,360],&quot;469777927&quot;:[0,0],&quot;469777928&quot;:[0,8]}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Zhao et al. (May<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><i><span data-contrast=\"none\">1<\/span><\/i><i><span data-contrast=\"none\">,\u00a0<\/span><\/i><i><span data-contrast=\"none\">2020). Early Detection of SARS-CoV-2 Antibodies in COVID-19 Patients as a Serologic Marker of Infection<\/span><\/i><i><span data-contrast=\"none\">. Clinical Infectious Diseases.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa523\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1093\/cid\/ciaa523<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Using CHO cell expressed full length\u00a0SARS-CoV-2 S1 protein as capturing antigen, Zhao et al. develop and validate a rapid COVID-19 serology ELISA kit able to detect SARS-CoV-2 antibody 1 day\u00a0after the onset of COVID-19. The reported specificity and sensitivity of the ELISA kit was 97.5% and 97.1%, respectively, with overall accuracy rate of 97.3%\u00a0(based on&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/04\/early-detection-of-sars-cov-2-antibodies-in-covid-19-patients-as-a-serologic-marker-of-infection\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-6613","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6613","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6613"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6613\/revisions"}],"predecessor-version":[{"id":6614,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6613\/revisions\/6614"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6613"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6613"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6613"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6613"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}