{"id":6660,"date":"2020-05-06T15:25:13","date_gmt":"2020-05-06T22:25:13","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6660"},"modified":"2021-03-16T15:25:58","modified_gmt":"2021-03-16T22:25:58","slug":"test-agreement-between-roche-cobas-6800-and-cepheid-genexpert-xpress-sars-cov-2-assays-at-high-cycle-threshold-ranges","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/06\/test-agreement-between-roche-cobas-6800-and-cepheid-genexpert-xpress-sars-cov-2-assays-at-high-cycle-threshold-ranges\/","title":{"rendered":"Test Agreement Between Roche Cobas 6800 and Cepheid GeneXpert Xpress SARS-CoV-2\u00a0Assays at High Cycle Threshold Ranges"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Broder et al. compared the\u00a0<\/span><span data-contrast=\"auto\">positive test agreement between<\/span><span data-contrast=\"auto\">\u00a0the<\/span><span data-contrast=\"auto\">\u00a0Roche\u00a0cobas\u00a06800 assay and the Cepheid GeneXpert Xpress SARS-CoV-2 assay<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">Thirty-five nasopharyngeal samples\u00a0<\/span><span data-contrast=\"auto\">with low viral loads (<\/span><span data-contrast=\"auto\">cycle threshold values &gt;30<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">\u00a0from the\u00a0cobas\u00a06800 were run on the GeneXpert<\/span><span data-contrast=\"auto\">\u00a0platform<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">The close agreement between the two\u00a0<\/span><span data-contrast=\"auto\">test<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">conducted on samples with low viral concentration<\/span><span data-contrast=\"auto\">\u00a0indicates<\/span><span data-contrast=\"auto\">\u00a0that the two<\/span><span data-contrast=\"auto\">\u00a0assays\u00a0<\/span><span data-contrast=\"auto\">could be used\u00a0<\/span><span data-contrast=\"auto\">interchangeable in accordance with testing algorithms.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Broder et al. (<\/span><\/i><i><span data-contrast=\"none\">May 5<\/span><\/i><i><span data-contrast=\"none\">, 2020). Test Agreement Between Roche Cobas 6800 and Cepheid GeneXpert Xpress SARS-CoV-2\u00a0<\/span><\/i><i><span data-contrast=\"none\">Assays at High Cycle Threshold Ranges<\/span><\/i><i><span data-contrast=\"none\">.<\/span><\/i><i><span data-contrast=\"none\">\u00a0Pre-print\u00a0downloaded May\u00a0<\/span><\/i><i><span data-contrast=\"none\">6<\/span><\/i><i><span data-contrast=\"none\">\u00a0from<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.05.05.078501\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.05.078501<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Broder et al. compared the\u00a0positive test agreement between\u00a0the\u00a0Roche\u00a0cobas\u00a06800 assay and the Cepheid GeneXpert Xpress SARS-CoV-2 assay.\u00a0Thirty-five nasopharyngeal samples\u00a0with low viral loads (cycle threshold values &gt;30)\u00a0from the\u00a0cobas\u00a06800 were run on the GeneXpert\u00a0platform.\u00a0The close agreement between the two\u00a0tests\u00a0conducted on samples with low viral concentration\u00a0indicates\u00a0that the two\u00a0assays\u00a0could be used\u00a0interchangeable in accordance with testing algorithms.\u00a0 Broder et al. (May&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/06\/test-agreement-between-roche-cobas-6800-and-cepheid-genexpert-xpress-sars-cov-2-assays-at-high-cycle-threshold-ranges\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_members_access_role":[],"_members_access_error":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-6660","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6660","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6660"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6660\/revisions"}],"predecessor-version":[{"id":6661,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6660\/revisions\/6661"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6660"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6660"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6660"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6660"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}