{"id":6687,"date":"2020-05-07T15:39:55","date_gmt":"2020-05-07T22:39:55","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6687"},"modified":"2021-03-16T15:40:44","modified_gmt":"2021-03-16T22:40:44","slug":"efficient-prevalence-estimation-and-infected-sample-identification-with-group-testing-for-sars-cov-2","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/07\/efficient-prevalence-estimation-and-infected-sample-identification-with-group-testing-for-sars-cov-2\/","title":{"rendered":"Efficient Prevalence Estimation and Infected Sample Identification with Group Testing for SARS-CoV-2"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"36\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Group testing of samples for the presence of SARS-CoV2 involves pooling samples from multiple individuals and testing individual samples only if the pool is positive. This strategy can<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">greatly increase testing\u00a0<\/span><span data-contrast=\"auto\">efficiency. This is especially critical\u00a0<\/span><span data-contrast=\"auto\">during the use w<\/span><span data-contrast=\"auto\">idespread screening and isolation\u00a0<\/span><span data-contrast=\"auto\">as a part of<\/span><span data-contrast=\"auto\">\u00a0primary\u00a0<\/span><span data-contrast=\"auto\">control measures\u00a0<\/span><span data-contrast=\"auto\">(i.e.,<\/span><span data-contrast=\"auto\">\u00a0absence of an effective therapeutic or vaccine<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"36\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Using a mathematical model to simulate changing viral loads over the course of an epidemic and compar<\/span><span data-contrast=\"auto\">ing different<\/span><span data-contrast=\"auto\">\u00a0pooling strategies for community screening, the<\/span><span data-contrast=\"auto\">\u00a0authors<\/span><span data-contrast=\"auto\">\u00a0sh<\/span><span data-contrast=\"auto\">ow group testing could ac<\/span><span data-contrast=\"auto\">curately estimate overall prevalence and increase\u00a0<\/span><span data-contrast=\"auto\">the identification of<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">infected<\/span><span data-contrast=\"auto\">\u00a0i<\/span><span data-contrast=\"auto\">n<\/span><span data-contrast=\"auto\">dividuals.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"36\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-contrast=\"auto\">I<\/span><span data-contrast=\"auto\">f group testing results in lower\u00a0<\/span><span data-contrast=\"auto\">sensitivity<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">it<\/span><span data-contrast=\"auto\">\u00a0will<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">increase<\/span><span data-contrast=\"auto\">\u00a0the\u00a0<\/span><span data-contrast=\"auto\">number<\/span><span data-contrast=\"auto\">\u00a0of false negatives.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Cleary<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al<\/span><\/i><i><span data-contrast=\"none\">. (May 6, 2020). Efficient Prevalence Estimation and Infected Sample Identification with Group Testing for SARS-CoV-2.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print downloaded May 7 from<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.05.01.20086801\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.01.20086801<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Group testing of samples for the presence of SARS-CoV2 involves pooling samples from multiple individuals and testing individual samples only if the pool is positive. This strategy can\u00a0greatly increase testing\u00a0efficiency. This is especially critical\u00a0during the use widespread screening and isolation\u00a0as a part of\u00a0primary\u00a0control measures\u00a0(i.e.,\u00a0absence of an effective therapeutic or vaccine).\u00a0\u00a0 Using a mathematical model to&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/07\/efficient-prevalence-estimation-and-infected-sample-identification-with-group-testing-for-sars-cov-2\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-6687","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6687","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6687"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6687\/revisions"}],"predecessor-version":[{"id":6688,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6687\/revisions\/6688"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6687"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6687"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6687"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6687"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}