{"id":6715,"date":"2020-05-08T15:55:24","date_gmt":"2020-05-08T22:55:24","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6715"},"modified":"2021-03-16T15:56:14","modified_gmt":"2021-03-16T22:56:14","slug":"occurrence-and-timing-of-subsequent-sars-cov-2-rt-pcr-positivity-among-initially-negative-patients","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/08\/occurrence-and-timing-of-subsequent-sars-cov-2-rt-pcr-positivity-among-initially-negative-patients\/","title":{"rendered":"Occurrence and Timing of Subsequent SARS-CoV-2 RT-PCR Positivity Among Initially Negative Patients"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Two independent research teams<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">from the<\/span><span data-contrast=\"auto\">\u00a0University of Washington (UW) and Stanford Health Care reported\u00a0<\/span><span data-contrast=\"auto\">a<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">similar frequency of discordant SARS-CoV-2 RT-PCR results among initially negative patients subjected to repeat testing. Among 626 patients who were initially test-negative and re-tested within 7 days, repeat testing yielded a positive result in 3.5% of cases<\/span><span data-contrast=\"auto\">\u00a0(4.3% UW, 2.8% Stanford)<\/span><span data-contrast=\"auto\">. The majority (96.5%) of patients with an initial negative result who warranted re-evaluation remained negative on subsequent tests performed within this window.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">These observations suggest that false negative results at the time of initial presentation do occur, but potentially at a lower frequency than what is currently believed<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Long<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al<\/span><\/i><i><span data-contrast=\"none\">.<\/span><\/i><i><span data-contrast=\"none\">\u00a0(May 8, 2020). Occurrence and Timing of Subsequent SARS-CoV-2 RT-PCR Positivity Among Initially Negative Patients. Pre-print downloaded May 8 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.05.03.20089151\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.03.20089151<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Two independent research teams\u00a0from the\u00a0University of Washington (UW) and Stanford Health Care reported\u00a0a\u00a0similar frequency of discordant SARS-CoV-2 RT-PCR results among initially negative patients subjected to repeat testing. Among 626 patients who were initially test-negative and re-tested within 7 days, repeat testing yielded a positive result in 3.5% of cases\u00a0(4.3% UW, 2.8% Stanford). The majority (96.5%)&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/08\/occurrence-and-timing-of-subsequent-sars-cov-2-rt-pcr-positivity-among-initially-negative-patients\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-6715","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6715","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6715"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6715\/revisions"}],"predecessor-version":[{"id":6716,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6715\/revisions\/6716"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6715"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6715"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6715"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6715"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}