{"id":6761,"date":"2020-05-11T16:33:12","date_gmt":"2020-05-11T23:33:12","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6761"},"modified":"2021-03-17T16:34:40","modified_gmt":"2021-03-17T23:34:40","slug":"liver-injury-is-associated-with-severe-coronavirus-disease-2019-covid-19-infection-a-systematic-review-and-meta-analysis-of-retrospective-studies","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/11\/liver-injury-is-associated-with-severe-coronavirus-disease-2019-covid-19-infection-a-systematic-review-and-meta-analysis-of-retrospective-studies\/","title":{"rendered":"Liver Injury Is Associated with Severe Coronavirus Disease 2019 (COVID-19) Infection: A Systematic Review and Meta-Analysis of Retrospective Studies"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">A\u00a0<\/span><span data-contrast=\"auto\">meta-analysis of retrospective studies summarize<\/span><span data-contrast=\"auto\">d<\/span><span data-contrast=\"auto\">\u00a0available findings on the association between liver injury and severity of COVID-19 infectio<\/span><span data-contrast=\"auto\">n.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">In total, 20 retrospective studies with 3,428 COVID-19 infected patients (severe cases = 1,455 and mild cases = 1,973), were included<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">The incidence of liver injury, as assessed by serum analysis (AST, ALT, total Bilirubin and Albumin levels), seems to be higher in patients with severe COVID-19\u00a0<\/span><span data-contrast=\"auto\">versus<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">mild<\/span><span data-contrast=\"auto\">\u00a0disease<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Parohan<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al. (May 9, 2020). Liver Injury Is Associated with Severe Coronavirus Disease 2019 (COVID-19) Infection: A Systematic Review and Meta-Analysis of Retrospective Studies.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Hepatology<\/span><\/i><i><span data-contrast=\"none\">\u00a0Research.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1111\/hepr.13510\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1111\/hepr.13510<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A\u00a0meta-analysis of retrospective studies summarized\u00a0available findings on the association between liver injury and severity of COVID-19 infection.\u00a0In total, 20 retrospective studies with 3,428 COVID-19 infected patients (severe cases = 1,455 and mild cases = 1,973), were included.\u00a0\u00a0The incidence of liver injury, as assessed by serum analysis (AST, ALT, total Bilirubin and Albumin levels), seems to&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/11\/liver-injury-is-associated-with-severe-coronavirus-disease-2019-covid-19-infection-a-systematic-review-and-meta-analysis-of-retrospective-studies\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-6761","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6761","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6761"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6761\/revisions"}],"predecessor-version":[{"id":6762,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6761\/revisions\/6762"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6761"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6761"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6761"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6761"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}