{"id":6775,"date":"2020-05-12T16:41:39","date_gmt":"2020-05-12T23:41:39","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6775"},"modified":"2021-03-17T16:57:00","modified_gmt":"2021-03-17T23:57:00","slug":"covid-19-literature-situation-report-may-12-2020","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/12\/covid-19-literature-situation-report-may-12-2020\/","title":{"rendered":"COVID-19 Literature Situation Report May 12, 2020"},"content":{"rendered":"<p>The scientific literature on COVID-19 is rapidly evolving and these articles were selected for review based on their relevance to Washington State decision making around COVID-19 response efforts. Included in these Lit Reps are some manuscripts that have been made available online as pre-prints but have not yet undergone peer review. Please be aware of this when reviewing articles included in the Lit Reps.<\/p>\n<h2>Key Takeaways<\/h2>\n<ul>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">An\u00a0<\/span><\/b><b><span data-contrast=\"auto\">age-stratified model calibrated Seattle, Washington\u00a0<\/span><\/b><b><span data-contrast=\"auto\">showed e<\/span><\/b><b><span data-contrast=\"auto\">arly implementation of social distancing interventions<\/span><\/b><b><span data-contrast=\"auto\">\u00a0would delay<\/span><\/b><b><span data-contrast=\"auto\">\u00a0the epidemic curve, while later implementation flattened it<\/span><\/b><b><span data-contrast=\"auto\">.\u00a0<\/span><\/b><b><span data-contrast=\"auto\">The<\/span><\/b><b><span data-contrast=\"auto\">\u00a0model<\/span><\/b><b><span data-contrast=\"auto\">\u00a0indicated that the\u00a0<\/span><\/b><b><span data-contrast=\"auto\">epidemic\u00a0<\/span><\/b><b><span data-contrast=\"auto\">would\u00a0<\/span><\/b><b><span data-contrast=\"auto\">rebounded after cessation\u00a0<\/span><\/b><b><span data-contrast=\"auto\">of social distancing\u00a0<\/span><\/b><b><span data-contrast=\"auto\">if testing and contact tracing were not performed.<\/span><\/b><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">A new approach to antigen testing uses expectorated saliva and does not require RNA purification,\u00a0<\/span><\/b><b><span data-contrast=\"auto\">removing<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">the need for swabs, RNA extraction kits, and healthcare personnel time\/PPE.<\/span><\/b><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">A multi-center cohort study found hydroxychloroquine alone or in combination with azithromycin\u00a0<\/span><\/b><b><span data-contrast=\"auto\">was associated with increased risk of\u00a0<\/span><\/b><b><span data-contrast=\"auto\">mortality, cardiac arrest, and abnormal ECG.\u00a0<\/span><\/b><b><span data-contrast=\"auto\">The only statistically significant association was between<\/span><\/b><b><span data-contrast=\"auto\">\u00a0combination therapy\u00a0<\/span><\/b><b><span data-contrast=\"auto\">and\u00a0<\/span><\/b><b><span data-contrast=\"auto\">cardiac arrest.<\/span><\/b><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"3\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">Readability of COVID-19 related materials on English language websites\u00a0<\/span><\/b><b><span data-contrast=\"auto\">is\u00a0<\/span><\/b><b><span data-contrast=\"auto\">generally at the 10<\/span><\/b><b><span data-contrast=\"auto\">th<\/span><\/b><b><span data-contrast=\"auto\">\u00a0grade level or higher and pandemic health literacy is generally low.\u00a0<\/span><\/b><b><span data-contrast=\"auto\">G<\/span><\/b><b><span data-contrast=\"auto\">uidelines on behavior\u00a0<\/span><\/b><b><span data-contrast=\"auto\">that are communicated to the public should be\u00a0<\/span><\/b><b><span data-contrast=\"auto\">accessible\u00a0<\/span><\/b><b><span data-contrast=\"auto\">at the lowest possible health literacy levels<\/span><\/b><b><span data-contrast=\"auto\">.\u00a0<\/span><\/b><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"4\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">Monitoring of over 12,000 travelers to California was labor intensive and yielded only 3 cases out of over 25,000 total cases.<\/span><\/b><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<div id=\"uw-accordion-shortcode\">\n<h3>Article Summaries<\/h3>\n<div class=\"js-accordion\" data-accordion-prefix-classes=\"uw-accordion-shortcode\">\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Non-Pharmaceutical Interventions<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-6776\" class=\"su-post\">\n<h5 class=\"su-post-title\">Evaluating the Effectiveness of Social Distancing Interventions to Delay or Flatten the Epidemic Curve of Coronavirus Disease<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"42\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Using an age-stratified model\u00a0<\/span><span data-contrast=\"auto\">calibrated to Seattle, Washington\u00a0<\/span><span data-contrast=\"auto\">in which social distancing interventions reduced contacts for 6 weeks, interventions started earlier in the epidemic were found to delay the epidemic curve, while interventions started later flatten<\/span><span data-contrast=\"auto\">ed<\/span><span data-contrast=\"auto\">\u00a0the epidemic curve. Even with only modest reductions in contacts among adults (20-59 years), interventions averted 20% of new cases, and most hospitalizations and deaths.\u00a0<\/span><span data-contrast=\"auto\">However<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0the\u00a0<\/span><span data-contrast=\"auto\">modeled\u00a0<\/span><span data-contrast=\"auto\">epidemic rebounded when interventions ended, suggesting that social distancing interventions must be implemented in conjunction with testing and contact tracing.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Matrajt<\/span><\/i><i><span data-contrast=\"none\">\u00a0and Leung. (Apr 28, 2020). Evaluating the Effectiveness of Social Distancing Interventions to Delay or Flatten the Epidemic Curve of Coronavirus Disease. Emerging Infectious Diseases.<\/span><\/i><i><span data-contrast=\"auto\">\u00a0<\/span><\/i><i><span data-contrast=\"none\">https:\/\/doi.org\/10.3201\/eid2608.201093<\/span><\/i><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Testing and Treatment<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-6782\" class=\"su-post\">\n<h5 class=\"su-post-title\">Use of Corticosteroids in Coronavirus Disease 2019 Pneumonia: A Systematic Review of the Literature<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"44\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">A systematic literature review<\/span><span data-contrast=\"auto\">\u00a0identified four studies<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">of corticosteroid use in patients with COVID-19 reported<\/span><span data-contrast=\"auto\">\u00a0through March 15, 2020<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">The effect of corticosteroids on clinical outcomes for COVID-19 was mixed, with corticosteroids\u00a0<\/span><span data-contrast=\"auto\">having<\/span><span data-contrast=\"auto\">\u00a0a\u00a0<\/span><span data-contrast=\"auto\">detrimental<\/span><span data-contrast=\"auto\">\u00a0impact in two out of four studies<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">One study\u00a0<\/span><span data-contrast=\"auto\">found that methylprednisolone could lower\u00a0<\/span><span data-contrast=\"auto\">the\u00a0<\/span><span data-contrast=\"auto\">mortality rate by 62%\u00a0<\/span><span data-contrast=\"auto\">among patients with\u00a0<\/span><span data-contrast=\"auto\">severe\u00a0<\/span><span data-contrast=\"auto\">COVID-19<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Veronese et al. (Apr 24, 2020). Use of Corticosteroids in Coronavirus Disease 2019 Pneumonia: A Systematic Review of the Literature. Frontiers in Medicine.<\/span><\/i><i><span data-contrast=\"auto\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.3389\/fmed.2020.00170\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.3389\/fmed.2020.00170<\/span><\/i><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-6780\" class=\"su-post\">\n<h5 class=\"su-post-title\">Association of Treatment\u00a0With\u00a0Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">A retrospective multi-center cohort study<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">sampled randomly from all admitted participants with laboratory-confirmed COVID-19 in 25 hospitals<\/span><span data-contrast=\"auto\">\u00a0(N=1,438)<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">and\u00a0<\/span><span data-contrast=\"auto\">compare<\/span><span data-contrast=\"auto\">d<\/span><span data-contrast=\"auto\">\u00a0hydroxychloroquine<\/span><span data-contrast=\"auto\">\u00a0alone, azithromycin\u00a0<\/span><span data-contrast=\"auto\">alone<\/span><span data-contrast=\"auto\">, and<\/span><span data-contrast=\"auto\">\u00a0combination of the two<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">relative\u00a0<\/span><span data-contrast=\"auto\">to treatment with neither medication<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li><span data-contrast=\"auto\">There was\u00a0<\/span><span data-contrast=\"auto\">a\u00a0<\/span><span data-contrast=\"auto\">greater odds of cardiac arrest in patients receiving<\/span><span data-contrast=\"auto\">\u00a0combination therapy (OR 2.13 95% CI: 1.12, 4.05), but otherwise\u00a0<\/span><span data-contrast=\"auto\">no\u00a0<\/span><span data-contrast=\"auto\">statistically significant associates with<\/span><span data-contrast=\"auto\">\u00a0mortality<\/span><span data-contrast=\"auto\">\u00a0or abnormal electrocardiogram findings<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">However, combination therapy had a non-significant<\/span><span data-contrast=\"auto\">\u00a0association<\/span><span data-contrast=\"auto\">\u00a0with increased risk of\u00a0<\/span><span data-contrast=\"auto\">mortality\u00a0<\/span><span data-contrast=\"auto\">(HR 1.35, 95% CI 0.76, 2.40)<\/span><span data-contrast=\"auto\">\u00a0and abnormal ECG findings (<\/span><span data-contrast=\"auto\">OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">1.55, 95%CI 0.89<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">2.67)<\/span><span data-contrast=\"auto\">, as did hydroxychloroquine alone for cardiac arrest<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">(<\/span><span data-contrast=\"auto\">OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">1.91, 95%CI: 0.96<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">3.81)<\/span><span data-contrast=\"auto\">\u00a0and abnormal ECG findings (<\/span><span data-contrast=\"auto\">OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">1.50, 95%CI: 0.88<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">2.58)<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">The effect of\u00a0<\/span><span data-contrast=\"auto\">h<\/span><span data-contrast=\"auto\">ydroxychloroquine alone\u00a0<\/span><span data-contrast=\"auto\">was also\u00a0<\/span><span data-contrast=\"auto\">non-significantly associate with a small increased risk of<\/span><span data-contrast=\"auto\">\u00a0mortality (<\/span><span data-contrast=\"auto\">HR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">1.08, 95%CI 0.63<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">1.85).\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Azithromycin alone\u00a0<\/span><span data-contrast=\"auto\">was associated with a\u00a0<\/span><span data-contrast=\"auto\">non-significant\u00a0<\/span><span data-contrast=\"auto\">lower risk of mortality\u00a0<\/span><span data-contrast=\"auto\">(<\/span><span data-contrast=\"auto\">HR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">0.56, 95%C<\/span><span data-contrast=\"auto\">I<\/span><span data-contrast=\"auto\">\u00a00.26<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">1.21<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0cardiac arrest (<\/span><span data-contrast=\"auto\">OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">0.64, 95%CI: 0.27<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">1.56)<\/span><span data-contrast=\"auto\">, and abnormal ECG findings (<\/span><span data-contrast=\"auto\">OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">0.95, 95%CI 0.77<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">3.24)<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-contrast=\"auto\">While\u00a0<\/span><span data-contrast=\"auto\">limited by the observational design<\/span><span data-contrast=\"auto\">, t<\/span><span data-contrast=\"auto\">hese findings provide\u00a0<\/span><span data-contrast=\"auto\">concerning\u00a0<\/span><span data-contrast=\"auto\">evidence that treatment with hydroxychloroquine is associated with a higher likelihood of mortality and adverse cardiac outcome<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">, and that addition of azithromycin may\u00a0<\/span><span data-contrast=\"auto\">increase th<\/span><span data-contrast=\"auto\">ese risks\u00a0<\/span><span data-contrast=\"auto\">further.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Rosenberg et al. (May 11, 2020). Association of Treatment\u00a0<\/span><\/i><i><span data-contrast=\"none\">With<\/span><\/i><i><span data-contrast=\"none\">\u00a0Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State. JAMA.<\/span><\/i><i><span data-contrast=\"auto\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jama.2020.8630\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jama.2020.8630<\/span><\/i><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-6778\" class=\"su-post\">\n<h5 class=\"su-post-title\">Rapid and Extraction-Free Detection of SARS-CoV-2 from Saliva with Colorimetric LAMP<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">S<\/span><span data-contrast=\"auto\">hortages in\u00a0<\/span><span data-contrast=\"auto\">testing\u00a0<\/span><span data-contrast=\"auto\">materials<\/span><span data-contrast=\"auto\">, including swabs, PPE, reagents, RNA extraction kits, and labor,<\/span><span data-contrast=\"auto\">\u00a0have restricted availability<\/span><span data-contrast=\"auto\">\u00a0of testing<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">A rapid colorimetric assay using the LAMP amplification method\u00a0<\/span><span data-contrast=\"auto\">demonstrated<\/span><span data-contrast=\"auto\">\u00a0high performance on expectorated saliva samples.\u00a0 This method does not require RNA purification or use of swabs<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0and can be self-collected,\u00a0<\/span><span data-contrast=\"auto\">which\u00a0<\/span><span data-contrast=\"auto\">reduc<\/span><span data-contrast=\"auto\">es<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">PPE and personnel needs.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Lalli<\/span><\/i><i><span data-contrast=\"none\">. (May 11, 2020). Rapid and Extraction-Free Detection of SARS-CoV-2 from Saliva with Colorimetric LAMP.<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><i><span data-contrast=\"none\">Pre-print downloaded May 12 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.05.07.20093542\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.07.20093542<\/span><\/i><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Clinical Characteristics and Health Care Setting<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-6790\" class=\"su-post\">\n<h5 class=\"su-post-title\">Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"41\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Shekerdemian<\/span><span data-contrast=\"auto\">\u00a0et al.\u00a0<\/span><span data-contrast=\"auto\">conducted a descriptive<\/span><span data-contrast=\"auto\">\u00a0study among\u00a0<\/span><span data-contrast=\"auto\">children\u00a0<\/span><span data-contrast=\"auto\">with<\/span><span data-contrast=\"auto\">\u00a0COVID-19 admitted to 46 PICUs\u00a0<\/span><span data-contrast=\"auto\">in<\/span><span data-contrast=\"auto\">\u00a0North America between mid-March and early April, 2020 (N=48<\/span><span data-contrast=\"auto\">). They found mean age was 13, 83% had significant pre-existing comorbidities, 38% required invasive ventilation,\u00a0<\/span><span data-contrast=\"auto\">and\u00a0<\/span><span data-contrast=\"auto\">23% had failure of 2 or more organ systems<\/span><span data-contrast=\"auto\">. While 4% had died at the time the study concluded, 15 patients (31%) remained hospitalized<\/span><span data-contrast=\"auto\">\u00a0and three\u00a0<\/span><span data-contrast=\"auto\">(6%) remained on ventilator support.<\/span><span data-contrast=\"auto\">\u00a0Targeted treatments were used in 61% of patients, with hydroxychloroquine, alone or in combination, being most commonly used.<\/span><span data-contrast=\"auto\">\u00a0The median PICU and hospital length<\/span><span data-contrast=\"auto\">s\u00a0<\/span><span data-contrast=\"auto\">of stay for those who were discharged was 5 and 7 days, respectively.\u00a0<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Shekerdemian<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al. (May 11, 2020). Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units. JAMA Pediatrics<\/span><\/i><i><span data-contrast=\"auto\">.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jamapediatrics.2020.1948\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jamapediatrics.2020.1948<\/span><\/i><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-6788\" class=\"su-post\">\n<h5 class=\"su-post-title\">Development and External Validation of a Prognostic Tool for COVID-19 Critical Disease<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"41\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Tools to predict COVID-19 severity\u00a0<\/span><span data-contrast=\"auto\">will assist in management of critical care capacity and enable earlier targeted interventions to improve outcomes. These authors created a web-based tool\u00a0<\/span><span data-contrast=\"auto\">for their<\/span><span data-contrast=\"auto\">\u00a0prognostic model<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0which defined critical disease as ICU admission, ventilation, or death. The<\/span><span data-contrast=\"auto\">y fit the<\/span><span data-contrast=\"auto\">\u00a0model\u00a0<\/span><span data-contrast=\"auto\">to\u00a0<\/span><span data-contrast=\"auto\">patients presenting to UC Irvine, and validated on patients presenting to Emory Healthcare. Covariates included comorbidities, presenting vital signs, and laboratory values. Model discrimination in the validation cohort was found to be high (concordance statistic 0.94, 95% CI: 0.87, 1.01).\u00a0\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Chow et al. (May 11, 2020). Development and External Validation of a Prognostic Tool for COVID-19 Critical Disease<\/span><\/i><i><span data-contrast=\"auto\">.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print downloaded May 12 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.05.06.20093435\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.06.20093435<\/span><\/i><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-6786\" class=\"su-post\">\n<h5 class=\"su-post-title\">CT Scans Obtained for\u00a0Nonpulmonary\u00a0Indications: Associated Respiratory Findings of COVID-19<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"41\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">As non-pulmonary manifestations of COVID-19 are being increasingly recognized,\u00a0<\/span><span data-contrast=\"auto\">Hossain et al.<\/span><span data-contrast=\"auto\">\u00a0evaluated the extent to which non-chest (abdomen\/pelvis or cervical spine\/neck) CT scans in patients with gastrointestinal or neurological symptoms detected findings highly suspicious for pulmonary COVID-19. Among\u00a0<\/span><span data-contrast=\"auto\">62<\/span><span data-contrast=\"auto\">\u00a0patients with suspected COVID-19 on presentation, non-chest CT findings provided the initial evidence of COVID-19 related pneumonia in 52% of patients. Among\u00a0<\/span><span data-contrast=\"auto\">57<\/span><span data-contrast=\"auto\">\u00a0patients without suspected COVID-19 at presentation, this figure was 77%. Patients who received cervical spine\/neck (those with neurological presentation) CT had worse outcomes than those who received abdominal\/pelvic CT.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Hossain et al. (May 11, 2020). CT Scans Obtained for\u00a0<\/span><\/i><i><span data-contrast=\"none\">Nonpulmonary<\/span><\/i><i><span data-contrast=\"none\">\u00a0Indications: Associated Respiratory Findings of COVID-19. Radiology.<\/span><\/i><i><span data-contrast=\"auto\">\u00a0<\/span><\/i><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1148\/radiol.2020201743<\/span><\/i><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-6784\" class=\"su-post\">\n<h5 class=\"su-post-title\">Rapid Isolation of Potent SARS-CoV-2 Neutralizing Antibodies and Protection in a Small Animal Model<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Rogers et al. screened over 1,000 antibodies for SARS-CoV-2 u<\/span><span data-contrast=\"auto\">sing serum from a cohort of recovered patients and an animal model (Syrian hamsters). They report multiple highly potent neutralizing antibodies, and demonstrate that passive transfer of these antibodies provides protection against a high dose viral challenge, suggesting potential for both prevention and treatment of COVID-19. These results may also be used to guide vaccine design.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Rogers<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al<\/span><\/i><i><span data-contrast=\"none\">. (May 11, 2020). Rapid Isolation of Potent SARS-CoV-2 Neutralizing Antibodies and Protection in a Small Animal Model.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print downloaded May 12 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.05.11.088674\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.11.088674<\/span><\/i><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Public Health Policy and Practice<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-6799\" class=\"su-post\">\n<h5 class=\"su-post-title\">Pandemic Related Health Literacy &#8211; A Systematic Review of Literature in COVID-19 SARS and MERS Pandemics<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">A literature review of health literacy related to COVID-19, MERS, and SARS, which included 70 articles, found low pandemic health literacy<\/span><span data-contrast=\"auto\">,\u00a0<\/span><span data-contrast=\"auto\">rang<\/span><span data-contrast=\"auto\">ing<\/span><span data-contrast=\"auto\">\u00a0from 4.3% to 57.9% among medical-related populations, and from 4% to 82.5% among non-medical populations.\u00a0<\/span><span data-contrast=\"auto\">The items most frequently evaluated were knowledge about symptoms and transmission, concern about infection, and practices related to mask use and hand hygiene.\u00a0<\/span><span data-contrast=\"auto\">Higher education level, older age, and female gender were associated with higher health literacy<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"auto\">Seng and YEAM. (May 11, 2020). Pandemic Related Health Literacy &#8211; A Systematic Review of Literature in COVID-19 SARS and MERS Pandemics.\u00a0<\/span><\/i><i><span data-contrast=\"auto\">Pre-print downloaded May 12 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.05.07.20094227\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.07.20094227<\/span><\/i><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-6797\" class=\"su-post\">\n<h5 class=\"su-post-title\">Public Health Response to COVID-19 Cases in Correctional and Detention Facilities \u2014 Louisiana, March\u2013April 2020<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">A COVID-19 Management Assessment and Response (CMAR) tool was used to assess 24 correctional facilities in Louisiana and identified general awareness and understanding of\u00a0<\/span><span data-contrast=\"auto\">prevention\u00a0<\/span><span data-contrast=\"auto\">guidance<\/span><span data-contrast=\"auto\">\u00a0among administrators<\/span><span data-contrast=\"auto\">. While limited ability to quarantine exposed persons and inability to engage in social distancing likely contributed to transmission in these facilities, the CMAR tool could be implemented more broadly to identify gaps in COVID-19 management practices.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"auto\">Wallace et al. (May 8, 2020). Public Health Response to COVID-19 Cases in Correctional and Detention Facilities \u2014 Louisiana, March\u2013April 2020. MMWR. Morbidity and Mortality Weekly Report.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.15585\/mmwr.mm6919e3\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.15585\/mmwr.mm6919e3<\/span><\/i><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-6795\" class=\"su-post\">\n<h5 class=\"su-post-title\">Identification and Monitoring of International Travelers During the Initial Phase of an Outbreak of COVID-19 \u2014 California, February 3\u2013March 17, 2020<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Between early February and mid<\/span><span data-contrast=\"auto\">&#8211;<\/span><span data-contrast=\"auto\">March<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">2020 almost 12,000 passengers from selected countries were screened upon entry to the US<\/span><span data-contrast=\"auto\">\u00a0and\u00a0<\/span><span data-contrast=\"auto\">monitored by local health jurisdictions in California.\u00a0<\/span><span data-contrast=\"auto\">Of\u00a0<\/span><span data-contrast=\"auto\">these,\u00a0<\/span><span data-contrast=\"auto\">3\u00a0<\/span><span data-contrast=\"auto\">travelers were matched to COVID-19 patients reported to the state by April 15<\/span><span data-contrast=\"auto\">th<\/span><span data-contrast=\"auto\">, out of over 25,000 cases overall. This effort was found to be labor-intensive and\u00a0<\/span><span data-contrast=\"auto\">its utility\u00a0<\/span><span data-contrast=\"auto\">limited by incomplete information and asymptomatic transmission<\/span><span data-contrast=\"auto\">. These efforts<\/span><span data-contrast=\"auto\">\u00a0have\u00a0<\/span><span data-contrast=\"auto\">diverted<\/span><span data-contrast=\"auto\">\u00a0resources needed for implementing other non-pharmaceutical interventions against COVID-19.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Myers et al. (May 11, 2020). Identification and Monitoring of International Travelers During the Initial Phase of an Outbreak of COVID-19 \u2014 California, February 3\u2013March 17, 2020. MMWR. Morbidity and Mortality Weekly Report.<\/span><\/i><i><span data-contrast=\"auto\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.15585\/mmwr.mm6919e4\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.15585\/mmwr.mm6919e4<\/span><\/i><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-6793\" class=\"su-post\">\n<h5 class=\"su-post-title\">Public Health Communication in Time of Crisis: Readability of On-Line COVID-19 Information<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">The mean readability score for the first 100 English language websites found using the search term \u201ccoronavirus\u201d\u00a0<\/span><span data-contrast=\"auto\">estimated<\/span><span data-contrast=\"auto\">\u00a0that readability levels for nearly all websites exceeded the 10<\/span><span data-contrast=\"auto\">th<\/span><span data-contrast=\"auto\">\u00a0grade<\/span><span data-contrast=\"auto\">\u00a0by at least four of five tests<\/span><span data-contrast=\"auto\">, with one test finding a mean readability level of grade 18 (graduate school level) across the sampled websites. The majority of COVID-19 messages are thus difficult for the average American to read<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">\u00a0Guidelines on behavior that are comm<\/span><span data-contrast=\"auto\">unicated to the public should\u00a0<\/span><span data-contrast=\"auto\">be readable at an \u201ceasy\u201d level.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Basch<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al. (May 11, 2020). Public Health Communication in Time of Crisis: Readability of On-Line COVID-19 Information. Disaster Medicine and Public Health Preparedness.<\/span><\/i><i><span data-contrast=\"auto\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1017\/dmp.2020.151\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1017\/dmp.2020.151<\/span><\/i><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<h3><strong>Other Resources and Commentaries<\/strong><\/h3>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"1\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1001\/jama.2020.7869\"><span data-contrast=\"none\">COVID-19 and\u00a0<\/span><span data-contrast=\"none\">Postinfection<\/span><span data-contrast=\"none\">\u00a0Immunity: Limited Evidence, Many Remaining Questions<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 JAMA\u00a0<\/span><br \/>\n<span data-contrast=\"auto\">(May 11)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"2\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/j.jinf.2020.05.008\"><span data-contrast=\"none\">Reactivation of COVID-19 pneumonia: a report of two cases<\/span><\/a><span data-contrast=\"none\">\u00a0\u2013 Journal of Infection (May 7)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"3\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/j.bbi.2020.05.025\"><span data-contrast=\"none\">Pain: A Potential New Label of COVID-19<\/span><\/a><span data-contrast=\"none\">\u00a0\u2013 Brain, Behavior, and Immunity (May 7)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"4\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.15585\/mmwr.mm6919e5\"><span data-contrast=\"none\">Preliminary Estimate of Excess Mortality During the COVID-19 Outbreak \u2014 New York City, March 11\u2013May 2, 2020<\/span><\/a><span data-contrast=\"none\">\u00a0\u2013 MMWR (May 11)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"1\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/j.jvb.2020.103436\"><span data-contrast=\"none\">Unemployment in the time of COVID-19: A research agenda<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Journal of Vocational Behavior\u00a0<\/span><br \/>\n<span data-contrast=\"auto\">(May 8)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>An age-stratified model calibrated Seattle, Washington showed early implementation of social distancing interventions would delay the epidemic curve, while later implementation flattened it. The model indicated that the epidemic would rebounded after cessation of social distancing if testing and contact tracing were not performed. <\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/12\/public-health-communication-in-time-of-crisis-readability-of-on-line-covid-19-information\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":5695,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[5],"tags":[],"topic":[],"class_list":["post-6775","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19-literature-situation-report"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6775","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6775"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6775\/revisions"}],"predecessor-version":[{"id":6802,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6775\/revisions\/6802"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media\/5695"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6775"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6775"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6775"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6775"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}