{"id":6782,"date":"2020-05-12T16:46:29","date_gmt":"2020-05-12T23:46:29","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6782"},"modified":"2021-03-17T16:47:25","modified_gmt":"2021-03-17T23:47:25","slug":"use-of-corticosteroids-in-coronavirus-disease-2019-pneumonia-a-systematic-review-of-the-literature","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/12\/use-of-corticosteroids-in-coronavirus-disease-2019-pneumonia-a-systematic-review-of-the-literature\/","title":{"rendered":"Use of Corticosteroids in Coronavirus Disease 2019 Pneumonia: A Systematic Review of the Literature"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"44\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">A systematic literature review<\/span><span data-contrast=\"auto\">\u00a0identified four studies<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">of corticosteroid use in patients with COVID-19 reported<\/span><span data-contrast=\"auto\">\u00a0through March 15, 2020<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">The effect of corticosteroids on clinical outcomes for COVID-19 was mixed, with corticosteroids\u00a0<\/span><span data-contrast=\"auto\">having<\/span><span data-contrast=\"auto\">\u00a0a\u00a0<\/span><span data-contrast=\"auto\">detrimental<\/span><span data-contrast=\"auto\">\u00a0impact in two out of four studies<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">One study\u00a0<\/span><span data-contrast=\"auto\">found that methylprednisolone could lower\u00a0<\/span><span data-contrast=\"auto\">the\u00a0<\/span><span data-contrast=\"auto\">mortality rate by 62%\u00a0<\/span><span data-contrast=\"auto\">among patients with\u00a0<\/span><span data-contrast=\"auto\">severe\u00a0<\/span><span data-contrast=\"auto\">COVID-19<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Veronese et al. (Apr 24, 2020). Use of Corticosteroids in Coronavirus Disease 2019 Pneumonia: A Systematic Review of the Literature. Frontiers in Medicine.<\/span><\/i><i><span data-contrast=\"auto\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.3389\/fmed.2020.00170\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.3389\/fmed.2020.00170<\/span><\/i><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A systematic literature review\u00a0identified four studies\u00a0of corticosteroid use in patients with COVID-19 reported\u00a0through March 15, 2020.\u00a0The effect of corticosteroids on clinical outcomes for COVID-19 was mixed, with corticosteroids\u00a0having\u00a0a\u00a0detrimental\u00a0impact in two out of four studies.\u00a0One study\u00a0found that methylprednisolone could lower\u00a0the\u00a0mortality rate by 62%\u00a0among patients with\u00a0severe\u00a0COVID-19.\u00a0 Veronese et al. (Apr 24, 2020). Use of Corticosteroids in Coronavirus&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/12\/use-of-corticosteroids-in-coronavirus-disease-2019-pneumonia-a-systematic-review-of-the-literature\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-6782","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6782","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6782"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6782\/revisions"}],"predecessor-version":[{"id":6783,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6782\/revisions\/6783"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6782"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6782"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6782"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6782"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}