{"id":6784,"date":"2020-05-12T16:47:31","date_gmt":"2020-05-12T23:47:31","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6784"},"modified":"2021-03-17T16:48:22","modified_gmt":"2021-03-17T23:48:22","slug":"rapid-isolation-of-potent-sars-cov-2-neutralizing-antibodies-and-protection-in-a-small-animal-model","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/12\/rapid-isolation-of-potent-sars-cov-2-neutralizing-antibodies-and-protection-in-a-small-animal-model\/","title":{"rendered":"Rapid Isolation of Potent SARS-CoV-2 Neutralizing Antibodies and Protection in a Small Animal Model"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Rogers et al. screened over 1,000 antibodies for SARS-CoV-2 u<\/span><span data-contrast=\"auto\">sing serum from a cohort of recovered patients and an animal model (Syrian hamsters). They report multiple highly potent neutralizing antibodies, and demonstrate that passive transfer of these antibodies provides protection against a high dose viral challenge, suggesting potential for both prevention and treatment of COVID-19. These results may also be used to guide vaccine design.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Rogers<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al<\/span><\/i><i><span data-contrast=\"none\">. (May 11, 2020). Rapid Isolation of Potent SARS-CoV-2 Neutralizing Antibodies and Protection in a Small Animal Model.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print downloaded May 12 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.05.11.088674\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.11.088674<\/span><\/i><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Rogers et al. screened over 1,000 antibodies for SARS-CoV-2 using serum from a cohort of recovered patients and an animal model (Syrian hamsters). They report multiple highly potent neutralizing antibodies, and demonstrate that passive transfer of these antibodies provides protection against a high dose viral challenge, suggesting potential for both prevention and treatment of COVID-19&#8230;.<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/12\/rapid-isolation-of-potent-sars-cov-2-neutralizing-antibodies-and-protection-in-a-small-animal-model\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_members_access_role":[],"_members_access_error":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-6784","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6784","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6784"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6784\/revisions"}],"predecessor-version":[{"id":6785,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6784\/revisions\/6785"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6784"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6784"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6784"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6784"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}