{"id":6788,"date":"2020-05-12T16:49:25","date_gmt":"2020-05-12T23:49:25","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6788"},"modified":"2021-03-17T16:50:12","modified_gmt":"2021-03-17T23:50:12","slug":"development-and-external-validation-of-a-prognostic-tool-for-covid-19-critical-disease","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/12\/development-and-external-validation-of-a-prognostic-tool-for-covid-19-critical-disease\/","title":{"rendered":"Development and External Validation of a Prognostic Tool for COVID-19 Critical Disease"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"41\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Tools to predict COVID-19 severity\u00a0<\/span><span data-contrast=\"auto\">will assist in management of critical care capacity and enable earlier targeted interventions to improve outcomes. These authors created a web-based tool\u00a0<\/span><span data-contrast=\"auto\">for their<\/span><span data-contrast=\"auto\">\u00a0prognostic model<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0which defined critical disease as ICU admission, ventilation, or death. The<\/span><span data-contrast=\"auto\">y fit the<\/span><span data-contrast=\"auto\">\u00a0model\u00a0<\/span><span data-contrast=\"auto\">to\u00a0<\/span><span data-contrast=\"auto\">patients presenting to UC Irvine, and validated on patients presenting to Emory Healthcare. Covariates included comorbidities, presenting vital signs, and laboratory values. Model discrimination in the validation cohort was found to be high (concordance statistic 0.94, 95% CI: 0.87, 1.01).\u00a0\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Chow et al. (May 11, 2020). Development and External Validation of a Prognostic Tool for COVID-19 Critical Disease<\/span><\/i><i><span data-contrast=\"auto\">.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print downloaded May 12 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.05.06.20093435\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.06.20093435<\/span><\/i><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tools to predict COVID-19 severity\u00a0will assist in management of critical care capacity and enable earlier targeted interventions to improve outcomes. These authors created a web-based tool\u00a0for their\u00a0prognostic model,\u00a0which defined critical disease as ICU admission, ventilation, or death. They fit the\u00a0model\u00a0to\u00a0patients presenting to UC Irvine, and validated on patients presenting to Emory Healthcare. Covariates included comorbidities,&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/12\/development-and-external-validation-of-a-prognostic-tool-for-covid-19-critical-disease\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-6788","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6788","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6788"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6788\/revisions"}],"predecessor-version":[{"id":6789,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6788\/revisions\/6789"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6788"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6788"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6788"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6788"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}