{"id":6918,"date":"2020-05-18T12:40:56","date_gmt":"2020-05-18T19:40:56","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6918"},"modified":"2021-03-18T12:41:44","modified_gmt":"2021-03-18T19:41:44","slug":"establishment-of-an-african-green-monkey-model-for-covid-19","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/18\/establishment-of-an-african-green-monkey-model-for-covid-19\/","title":{"rendered":"Establishment of an African Green Monkey Model for COVID-19"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"37\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">African green\u00a0<\/span><span data-contrast=\"auto\">monkeys can be used as an animal mode for SARS-CoV-2 infection. African green monkeys experience<\/span><span data-contrast=\"auto\">\u00a0high level<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">\u00a0of SARS-CoV-2 replication and develop pronounced respiratory disease<\/span><span data-contrast=\"auto\">\u00a0following\u00a0<\/span><span data-contrast=\"auto\">a much lower and more natural dose of SARS-CoV-2 than has been employed in other\u00a0<\/span><span data-contrast=\"auto\">non-human primate\u00a0<\/span><span data-contrast=\"auto\">studies.<\/span><span data-contrast=\"auto\">\u00a0The heterologous response of\u00a0<\/span><span data-contrast=\"auto\">African green monkeys\u00a0<\/span><span data-contrast=\"auto\">along with the ability to collect tissues and longitudinal samples permits a detailed study of pathogenesis and\u00a0<\/span><span data-contrast=\"auto\">host\u00a0<\/span><span data-contrast=\"auto\">immunity to COVID-19.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Woolsey et al. (May 17, 2020). Establishment of an African Green Monkey Model for COVID-19. Pre-print\u00a0downloaded May 18 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.05.17.100289\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.17.100289<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>African green\u00a0monkeys can be used as an animal mode for SARS-CoV-2 infection. African green monkeys experience\u00a0high levels\u00a0of SARS-CoV-2 replication and develop pronounced respiratory disease\u00a0following\u00a0a much lower and more natural dose of SARS-CoV-2 than has been employed in other\u00a0non-human primate\u00a0studies.\u00a0The heterologous response of\u00a0African green monkeys\u00a0along with the ability to collect tissues and longitudinal samples permits a&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/18\/establishment-of-an-african-green-monkey-model-for-covid-19\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-6918","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6918","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6918"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6918\/revisions"}],"predecessor-version":[{"id":6919,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6918\/revisions\/6919"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6918"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6918"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6918"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6918"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}