{"id":6997,"date":"2020-05-20T15:48:11","date_gmt":"2020-05-20T22:48:11","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=6997"},"modified":"2021-03-19T15:49:06","modified_gmt":"2021-03-19T22:49:06","slug":"emerging-phylogenetic-structure-of-the-sars-cov-2-pandemic","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/20\/emerging-phylogenetic-structure-of-the-sars-cov-2-pandemic\/","title":{"rendered":"Emerging Phylogenetic Structure of the SARS-CoV-2 Pandemic"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Fountain-Jones et al.\u00a0<\/span><span data-contrast=\"auto\">studied the phylogenetic structures underlying the SARS-CoV-2 pandemic and\u00a0find\u00a0support for three distinct lineages, each having different demographic trajectories. While\u00a0the majority of\u00a0sequences classified in\u00a0<\/span><span data-contrast=\"auto\">L<\/span><span data-contrast=\"auto\">ineage\u00a0<\/span><span data-contrast=\"auto\">A and B originated in China and\u00a0<\/span><span data-contrast=\"auto\">have been\u00a0<\/span><span data-contrast=\"auto\">subsequently found in Washington State and\u00a0<\/span><span data-contrast=\"auto\">throughout\u00a0<\/span><span data-contrast=\"auto\">the US,\u00a0<\/span><span data-contrast=\"auto\">L<\/span><span data-contrast=\"auto\">ineage\u00a0<\/span><span data-contrast=\"auto\">C was predominantly European with no<\/span><span data-contrast=\"auto\">\u00a0evidence<\/span><span data-contrast=\"auto\">\u00a0that it circulated in China.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Demographic dynamics of the lineages are also concordant with known epidemiologic factors &#8211; for instance mutations affecting the increase in viral mutation rate specific to Lineage C support the hypothesis that Lineage C may have increased transmissibility compared to other lineages<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Fountain-Jones et al. (May 19, 2020). Emerging Phylogenetic Structure of the SARS-CoV-2 Pandemic.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print\u00a0downloaded May 20 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.05.19.103846\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.19.103846<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Fountain-Jones et al.\u00a0studied the phylogenetic structures underlying the SARS-CoV-2 pandemic and\u00a0find\u00a0support for three distinct lineages, each having different demographic trajectories. While\u00a0the majority of\u00a0sequences classified in\u00a0Lineage\u00a0A and B originated in China and\u00a0have been\u00a0subsequently found in Washington State and\u00a0throughout\u00a0the US,\u00a0Lineage\u00a0C was predominantly European with no\u00a0evidence\u00a0that it circulated in China.\u00a0 Demographic dynamics of the lineages are also concordant&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/20\/emerging-phylogenetic-structure-of-the-sars-cov-2-pandemic\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[21],"class_list":["post-6997","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-transmission"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6997","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=6997"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6997\/revisions"}],"predecessor-version":[{"id":6998,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/6997\/revisions\/6998"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=6997"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=6997"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=6997"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=6997"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}