{"id":7037,"date":"2020-05-21T16:12:52","date_gmt":"2020-05-21T23:12:52","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7037"},"modified":"2021-03-19T16:13:33","modified_gmt":"2021-03-19T23:13:33","slug":"symptomatic-infants-have-higher-nasopharyngeal-sars-cov-2-viral-loads-but-less-severe-disease-than-older-children","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/21\/symptomatic-infants-have-higher-nasopharyngeal-sars-cov-2-viral-loads-but-less-severe-disease-than-older-children\/","title":{"rendered":"Symptomatic Infants Have Higher Nasopharyngeal SARS-CoV-2 Viral Loads but Less Severe Disease than Older Children"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Among 57 SARS-CoV-2 positive patients admitted to a children\u2019s hospital<\/span><span data-contrast=\"auto\">\u00a0in China<\/span><span data-contrast=\"auto\">, 20 (35%) were infants and 37 (65%) were children and adolescents. Although the mean nasopharyngeal viral load was higher in infants (21.1 v<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">. 27.3 Ct, p-value &lt; 0.001), a lower proportion of infants had severe disease: 1 (5%) infant compared to 12 (32%) of older children (p=0.02).<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Zachariah et al. (May 20, 2020). Symptomatic Infants Have Higher Nasopharyngeal SARS-CoV-2 Viral Loads but Less Severe Disease than Older Children. Clinical Infectious Diseases.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa608\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1093\/cid\/ciaa608<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Among 57 SARS-CoV-2 positive patients admitted to a children\u2019s hospital\u00a0in China, 20 (35%) were infants and 37 (65%) were children and adolescents. Although the mean nasopharyngeal viral load was higher in infants (21.1 vs. 27.3 Ct, p-value &lt; 0.001), a lower proportion of infants had severe disease: 1 (5%) infant compared to 12 (32%) of&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/21\/symptomatic-infants-have-higher-nasopharyngeal-sars-cov-2-viral-loads-but-less-severe-disease-than-older-children\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-7037","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7037","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7037"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7037\/revisions"}],"predecessor-version":[{"id":7038,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7037\/revisions\/7038"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7037"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7037"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7037"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7037"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}