{"id":7063,"date":"2020-05-22T16:26:49","date_gmt":"2020-05-22T23:26:49","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7063"},"modified":"2021-03-19T16:27:37","modified_gmt":"2021-03-19T23:27:37","slug":"immunogenic-profile-of-sars-cov-2-spike-in-individuals-recovered-from-covid-19","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/22\/immunogenic-profile-of-sars-cov-2-spike-in-individuals-recovered-from-covid-19\/","title":{"rendered":"Immunogenic Profile of SARS-CoV-2 Spike in Individuals Recovered from COVID-19"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"39\" data-aria-posinset=\"1\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[<\/span><\/i><i><span data-contrast=\"none\">pre-print, not peer reviewed<\/span><\/i><i><span data-contrast=\"none\">]<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Juno et al.\u00a0<\/span><span data-contrast=\"auto\">found\u00a0<\/span><span data-contrast=\"auto\">that follo<\/span><span data-contrast=\"auto\">wing mild to moderate\u00a0<\/span><span data-contrast=\"auto\">SARS-CoV-2 infection, antibody responses against the viral spike protein are routinely elicited and that they are correlate with the ability of blood plasma to block binding to the ACE2 receptor. This has positive implications for vaccine development because s<\/span><span data-contrast=\"auto\">everal COVID-19 vaccine candidates\u00a0<\/span><span data-contrast=\"auto\">that<\/span><span data-contrast=\"auto\">\u00a0are now entering clinical trials are designed to elicit antibodies<\/span><span data-contrast=\"auto\">\u00a0that\u00a0<\/span><span data-contrast=\"auto\">target\u00a0the viral\u00a0spike glycoprotein.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Juno et al. (May 21, 2020). Immunogenic Profile of SARS-CoV-2 Spike in Individuals Recovered from COVID-19.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print\u00a0downloaded May 21 from<\/span><\/i><i><span data-contrast=\"auto\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.05.17.20104869\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.17.20104869<\/span><\/i><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[pre-print, not peer reviewed]\u00a0Juno et al.\u00a0found\u00a0that following mild to moderate\u00a0SARS-CoV-2 infection, antibody responses against the viral spike protein are routinely elicited and that they are correlate with the ability of blood plasma to block binding to the ACE2 receptor. This has positive implications for vaccine development because several COVID-19 vaccine candidates\u00a0that\u00a0are now entering clinical trials&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/22\/immunogenic-profile-of-sars-cov-2-spike-in-individuals-recovered-from-covid-19\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[31],"class_list":["post-7063","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7063","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7063"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7063\/revisions"}],"predecessor-version":[{"id":7064,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7063\/revisions\/7064"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7063"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7063"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7063"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7063"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}