{"id":7130,"date":"2020-05-27T17:20:33","date_gmt":"2020-05-28T00:20:33","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7130"},"modified":"2021-03-19T17:21:28","modified_gmt":"2021-03-20T00:21:28","slug":"correlation-between-viral-rna-shedding-and-serum-antibodies-in-covid-19-patients","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/27\/correlation-between-viral-rna-shedding-and-serum-antibodies-in-covid-19-patients\/","title":{"rendered":"Correlation between viral RNA shedding and serum antibodies in COVID-19 patients"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Jin\u00a0et al.\u00a0<\/span><span data-contrast=\"auto\">found that among\u00a0<\/span><span data-contrast=\"auto\">SARS-CoV-2 infection\u00a0<\/span><span data-contrast=\"auto\">cases<\/span><span data-contrast=\"auto\">\u00a0(n=89),\u00a0<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">erum IgM was significantly higher\u00a0<\/span><span data-contrast=\"auto\">among<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">those\u00a0<\/span><span data-contrast=\"auto\">with\u00a0<\/span><span data-contrast=\"auto\">prolonged viral RNA shedding (&gt;30 days)<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">at week<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">\u00a04 and 5 after symptom onset,\u00a0<\/span><span data-contrast=\"auto\">IgM levels were\u00a0<\/span><span data-contrast=\"auto\">similar between\u00a0<\/span><span data-contrast=\"auto\">prolong<\/span><span data-contrast=\"auto\">ed<\/span><span data-contrast=\"auto\">\u00a0and non-prolonged shedders\u00a0<\/span><span data-contrast=\"auto\">from week<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">\u00a06 to\u00a08, and\u00a0declined almost to the reference level in both groups at week 8.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Serum IgM<\/span><span data-contrast=\"auto\">\u00a0persisted at\u00a0<\/span><span data-contrast=\"auto\">a high level during the acute\u00a0<\/span><span data-contrast=\"auto\">illness\u00a0<\/span><span data-contrast=\"auto\">and\u00a0<\/span><span data-contrast=\"auto\">up to\u00a0<\/span><span data-contrast=\"auto\">8\u00a0<\/span><span data-contrast=\"auto\">week<\/span><span data-contrast=\"auto\">s after\u00a0symptom\u00a0onset<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Jin\u00a0et al. (May 18, 2020). Correlation between viral RNA shedding and serum antibodies in COVID-19 patients. Clinical Microbiology and Infection.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.cmi.2020.05.022\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.cmi.2020.05.022<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Jin\u00a0et al.\u00a0found that among\u00a0SARS-CoV-2 infection\u00a0cases\u00a0(n=89),\u00a0serum IgM was significantly higher\u00a0among\u00a0those\u00a0with\u00a0prolonged viral RNA shedding (&gt;30 days)\u00a0at weeks\u00a04 and 5 after symptom onset,\u00a0IgM levels were\u00a0similar between\u00a0prolonged\u00a0and non-prolonged shedders\u00a0from weeks\u00a06 to\u00a08, and\u00a0declined almost to the reference level in both groups at week 8.\u00a0 Serum IgM\u00a0persisted at\u00a0a high level during the acute\u00a0illness\u00a0and\u00a0up to\u00a08\u00a0weeks after\u00a0symptom\u00a0onset.\u00a0 Jin\u00a0et al. (May 18, 2020). Correlation&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/27\/correlation-between-viral-rna-shedding-and-serum-antibodies-in-covid-19-patients\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[21],"class_list":["post-7130","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-transmission"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7130","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7130"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7130\/revisions"}],"predecessor-version":[{"id":7131,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7130\/revisions\/7131"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7130"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7130"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7130"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7130"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}