{"id":715,"date":"2020-09-03T13:28:44","date_gmt":"2020-09-03T20:28:44","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=715"},"modified":"2020-09-08T13:29:38","modified_gmt":"2020-09-08T20:29:38","slug":"effect-of-hydrocortisone-on-mortality-and-organ-support-in-patients-with-severe-covid-19","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/03\/effect-of-hydrocortisone-on-mortality-and-organ-support-in-patients-with-severe-covid-19\/","title":{"rendered":"Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19"},"content":{"rendered":"<ul>\n<li>Administration of hydrocortisone, either as a 7-day fixed-dose course, or dosing only during periods of shock, was associated with being alive and free of ICU-based respiratory or cardiovascular support within 21 days, according to findings of a randomized control trial (n=384) which was stopped early after results were released from another trial. The fixed-dose course and shock-dependent dosing resulted in Bayesian probabilities of superiority of 93% and 80%, respectively.<\/li>\n<\/ul>\n<p><em>Angus et al. (Sept 2, 2020). Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19. JAMA. <a href=\"https:\/\/doi.org\/10.1001\/jama.2020.17022\">https:\/\/doi.org\/10.1001\/jama.2020.17022<\/a><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Administration of hydrocortisone, either as a 7-day fixed-dose course, or dosing only during periods of shock, was associated with being alive and free of ICU-based respiratory or cardiovascular support within 21 days, according to findings of a randomized control trial (n=384) which was stopped early after results were released from another trial. The fixed-dose course&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/03\/effect-of-hydrocortisone-on-mortality-and-organ-support-in-patients-with-severe-covid-19\/\">Read more<\/a><\/div>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[28],"topic":[19],"class_list":["post-715","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-treatment","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/715","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=715"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/715\/revisions"}],"predecessor-version":[{"id":716,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/715\/revisions\/716"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=715"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=715"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=715"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=715"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}