{"id":717,"date":"2020-09-03T13:52:23","date_gmt":"2020-09-03T20:52:23","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=717"},"modified":"2020-09-08T13:53:17","modified_gmt":"2020-09-08T20:53:17","slug":"effect-of-dexamethasone-on-days-alive-and-ventilator-free-in-patients-with-moderate-or-severe-acute-respiratory-distress-syndrome-and-covid-19","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/03\/effect-of-dexamethasone-on-days-alive-and-ventilator-free-in-patients-with-moderate-or-severe-acute-respiratory-distress-syndrome-and-covid-19\/","title":{"rendered":"Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19"},"content":{"rendered":"<ul>\n<li>Intravenous dexamethasone plus standard of care compared with standard care alone resulted in 2.3 days (95%CI 0.02-4.4, p=0.04) more ventilator-free days during the first 28 days in a randomized clinical trial among patients with COVID-19 who had moderate to severe respiratory failure (n=299) in Brazil.<\/li>\n<li>The trial was stopped early before reaching the planned sample size of 350 patients following publication of a related study.<\/li>\n<\/ul>\n<p><em>Tomazini et al. (Sept 2, 2020). Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19. JAMA. <a href=\"https:\/\/doi.org\/10.1001\/jama.2020.17021\">https:\/\/doi.org\/10.1001\/jama.2020.17021<\/a><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Intravenous dexamethasone plus standard of care compared with standard care alone resulted in 2.3 days (95%CI 0.02-4.4, p=0.04) more ventilator-free days during the first 28 days in a randomized clinical trial among patients with COVID-19 who had moderate to severe respiratory failure (n=299) in Brazil. The trial was stopped early before reaching the planned sample&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/03\/effect-of-dexamethasone-on-days-alive-and-ventilator-free-in-patients-with-moderate-or-severe-acute-respiratory-distress-syndrome-and-covid-19\/\">Read more<\/a><\/div>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[28],"topic":[19],"class_list":["post-717","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-treatment","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/717","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=717"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/717\/revisions"}],"predecessor-version":[{"id":718,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/717\/revisions\/718"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=717"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=717"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=717"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=717"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}