{"id":7223,"date":"2020-05-29T12:15:31","date_gmt":"2020-05-29T19:15:31","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7223"},"modified":"2021-03-24T12:16:24","modified_gmt":"2021-03-24T19:16:24","slug":"the-non-specific-and-sex-differential-effects-of-vaccines","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/29\/the-non-specific-and-sex-differential-effects-of-vaccines\/","title":{"rendered":"The Non-Specific and Sex-Differential Effects of Vaccines"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Aaby et al. review s<\/span><span data-contrast=\"auto\">tudies show<\/span><span data-contrast=\"auto\">ing<\/span><span data-contrast=\"auto\">\u00a0that live vaccines like BCG\u00a0<\/span><span data-contrast=\"auto\">have<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">non-specific effects<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">including<\/span><span data-contrast=\"auto\">\u00a0protection against respiratory and viral infections<\/span><span data-contrast=\"auto\">, and that f<\/span><span data-contrast=\"auto\">emales develop a greater antibody response to BCG. There is no conclusive evidence, however, that BCG\u00a0<\/span><span data-contrast=\"auto\">vaccination\u00a0<\/span><span data-contrast=\"auto\">provide<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">\u00a0non-specific protection against COVID-19, and social justice issues\u00a0<\/span><span data-contrast=\"auto\">could<\/span><span data-contrast=\"auto\">\u00a0arise from shifting BCG vaccine supplies from\u00a0<\/span><span data-contrast=\"auto\">low<\/span><span data-contrast=\"auto\">&#8211;<\/span><span data-contrast=\"auto\">\u00a0to high<\/span><span data-contrast=\"auto\">&#8211;<\/span><span data-contrast=\"auto\">income countries<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Aaby et al. (May 27, 2020). The Non-Specific and Sex-Differential Effects of Vaccines. Nature Reviews Immunology.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1038\/s41577-020-0338-x\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1038\/s41577-020-0338-x<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Aaby et al. review studies showing\u00a0that live vaccines like BCG\u00a0have\u00a0non-specific effects\u00a0including\u00a0protection against respiratory and viral infections, and that females develop a greater antibody response to BCG. There is no conclusive evidence, however, that BCG\u00a0vaccination\u00a0provides\u00a0non-specific protection against COVID-19, and social justice issues\u00a0could\u00a0arise from shifting BCG vaccine supplies from\u00a0low&#8211;\u00a0to high&#8211;income countries.\u00a0 Aaby et al. (May 27, 2020)&#8230;.<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/05\/29\/the-non-specific-and-sex-differential-effects-of-vaccines\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[31],"class_list":["post-7223","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7223","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7223"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7223\/revisions"}],"predecessor-version":[{"id":7224,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7223\/revisions\/7224"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7223"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7223"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7223"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7223"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}