{"id":7235,"date":"2020-06-01T12:30:53","date_gmt":"2020-06-01T19:30:53","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7235"},"modified":"2021-03-24T12:47:24","modified_gmt":"2021-03-24T19:47:24","slug":"covid-19-literature-situation-report-june-1-2020","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/01\/covid-19-literature-situation-report-june-1-2020\/","title":{"rendered":"COVID-19 Literature Situation Report June 1, 2020"},"content":{"rendered":"<p>The scientific literature on COVID-19 is rapidly evolving and these articles were selected for review based on their relevance to Washington State decision making around COVID-19 response efforts. Included in these Lit Reps are some manuscripts that have been made available online as pre-prints but have not yet undergone peer review. Please be aware of this when reviewing articles included in the Lit Reps.<\/p>\n<h2>Key Takeaways<\/h2>\n<ul>\n<li><b><span data-contrast=\"auto\">Better ventilation substantially reduces\u00a0<\/span><\/b><b><span data-contrast=\"auto\">the amount of time<\/span><\/b><b><span data-contrast=\"auto\">\u00a0respiratory droplets<\/span><\/b><b><span data-contrast=\"auto\">\u00a0are\u00a0<\/span><\/b><b><span data-contrast=\"auto\">airborne<\/span><\/b><b><span data-contrast=\"auto\">. This has potential implications for recommendations regarding avoidance of poorly\u00a0<\/span><\/b><b><span data-contrast=\"auto\">ventilated public spaces<\/span><\/b><b><span data-contrast=\"auto\">\u00a0and\u00a0<\/span><\/b><b><span data-contrast=\"auto\">for\u00a0<\/span><\/b><b><span data-contrast=\"auto\">hospital<\/span><\/b><b><span data-contrast=\"auto\">s<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">to\u00a0<\/span><\/b><b><span data-contrast=\"auto\">improve<\/span><\/b><b><span data-contrast=\"auto\">\u00a0ventilation\u00a0<\/span><\/b><b><span data-contrast=\"auto\">in settings\u00a0<\/span><\/b><b><span data-contrast=\"auto\">where aerosolization by coughing and close contact with COVID-19 patients is common.<\/span><\/b><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">Two subsequent generations of SARS-CoV-2 transmission were identified from persons attending a mass gathering, raising\u00a0<\/span><\/b><b><span data-contrast=\"auto\">the question<\/span><\/b><b><span data-contrast=\"auto\">\u00a0of whether<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">testing participants at\u00a0<\/span><\/b><b><span data-contrast=\"auto\">similar<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">events before cases are identified<\/span><\/b><b><span data-contrast=\"auto\">\u00a0could prevent additional\u00a0<\/span><\/b><b><span data-contrast=\"auto\">transmission.<\/span><\/b><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">The<\/span><\/b><b><span data-contrast=\"auto\">\u00a0first case of detectable SARS-CoV-2 RNA\u00a0<\/span><\/b><b><span data-contrast=\"auto\">in<\/span><\/b><b><span data-contrast=\"auto\">\u00a0human\u00a0<\/span><\/b><b><span data-contrast=\"auto\">breast<\/span><\/b><b><span data-contrast=\"auto\">milk<\/span><\/b><b><span data-contrast=\"auto\">\u00a0was reported<\/span><\/b><b><span data-contrast=\"auto\">. The significance of this finding\u00a0<\/span><\/b><b><span data-contrast=\"auto\">regarding the risk of mother-to-child transmission\u00a0<\/span><\/b><b><span data-contrast=\"auto\">is uncertain\u00a0<\/span><\/b><b><span data-contrast=\"auto\">given that<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">detectable RNA\u00a0<\/span><\/b><b><span data-contrast=\"auto\">does not necessarily<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">indicate\u00a0viable\u00a0virus.\u00a0<\/span><\/b><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"3\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">A multicenter study\u00a0<\/span><\/b><b><span data-contrast=\"auto\">found\u00a0<\/span><\/b><b><span data-contrast=\"auto\">no evidence\u00a0<\/span><\/b><b><span data-contrast=\"auto\">that\u00a0<\/span><\/b><b><span data-contrast=\"auto\">cancer patients on anticancer treatment\u00a0<\/span><\/b><b><span data-contrast=\"auto\">are\u00a0<\/span><\/b><b><span data-contrast=\"auto\">at increased risk of mortality from COVID-19.\u00a0<\/span><\/b><b><span data-contrast=\"auto\">This\u00a0<\/span><\/b><b><span data-contrast=\"auto\">raises the possibility\u00a0<\/span><\/b><b><span data-contrast=\"auto\">that w<\/span><\/b><b><span data-contrast=\"auto\">ithholding effective cancer treatments may\u00a0<\/span><\/b><b><span data-contrast=\"auto\">increase\u00a0risk\u00a0of cancer morbidity\u00a0<\/span><\/b><b><span data-contrast=\"auto\">and mortality<\/span><\/b><b><span data-contrast=\"auto\">\u00a0with no benefit of decreas<\/span><\/b><b><span data-contrast=\"auto\">ed<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">COVID-19<\/span><\/b><b><span data-contrast=\"auto\">\u00a0mortality<\/span><\/b><b><span data-contrast=\"auto\">.<\/span><\/b><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<div id=\"uw-accordion-shortcode\">\n<h3>Article Summaries<\/h3>\n<div class=\"js-accordion\" data-accordion-prefix-classes=\"uw-accordion-shortcode\">\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Non-Pharmaceutical Interventions<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7237\" class=\"su-post\">\n<h5 class=\"su-post-title\">Wastewater Surveillance for Population-Wide Covid-19:\u00a0The Present\u00a0and Future<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Daughton\u00a0<\/span><span data-contrast=\"auto\">described<\/span><span data-contrast=\"auto\">\u00a0t<\/span><span data-contrast=\"auto\">he Wastewater-Based Epidemiology (WBE)\u00a0<\/span><span data-contrast=\"auto\">method\u00a0<\/span><span data-contrast=\"auto\">as<\/span><span data-contrast=\"auto\">\u00a0a<\/span><span data-contrast=\"auto\">\u00a0potential tool\u00a0<\/span><span data-contrast=\"auto\">for<\/span><span data-contrast=\"auto\">\u00a0containing and mitigating COVID-19 outbreaks. WBE measures chemical signatures in sewage, such as fragment biomarkers from the SARS-CoV-2, by applying clinical diagnostic testing to the collective signature of entire communities.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Daughton. (May 20,\u00a02020).\u00a0Wastewater Surveillance for Population-Wide Covid-19:\u00a0The Present\u00a0and Future. The Science of the Total Environment.<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.scitotenv.2020.139631\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.scitotenv.2020.139631<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Transmission<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7251\" class=\"su-post\">\n<h5 class=\"su-post-title\">Introductions\u00a0and Early Spread of SARS-CoV-2 in the New York City Area<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Gonzalex-Reiche et al. report phylogenetic<\/span><span data-contrast=\"auto\">\u00a0analysis of<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">patients seeking care at the Mount Sinai Health System\u00a0<\/span><span data-contrast=\"auto\">in New York City\u00a0<\/span><span data-contrast=\"auto\">revealed 84 distinct SARS-CoV2 genomes,\u00a0<\/span><span data-contrast=\"auto\">corresponding to<\/span><span data-contrast=\"auto\">\u00a0multiple<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">independent introductions<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0mainly from Europe and other parts of the United States. There was also evidence for community transmission of SARS-CoV-2<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0as suggested by clusters of related viruses found in patients living in different neighborhoods of the city.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Gonzalez-Reiche et al. (May 29, 2020).\u00a0Introductions\u00a0and Early Spread of SARS-CoV-2 in the New York City Area. Science.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1126\/science.abc1917\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1126\/science.abc1917<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7249\" class=\"su-post\">\n<h5 class=\"su-post-title\">The Novel Coronavirus SARS-CoV-2: From a Zoonotic Infection to Coronavirus Disease-19 (COVID19)<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">A phylogenetic analysis reconstructed from\u00a0CoV\u00a0strains demonstrated that SARS-CoV-2, bat RaTG13 and pangolin\u00a0CoV\u00a0genomes formed a cluster, suggesting\u00a0<\/span><span data-contrast=\"auto\">a close<\/span><span data-contrast=\"auto\">\u00a0relationship between SARS-CoV-2 and bat SARS-like strains, and\u00a0<\/span><span data-contrast=\"auto\">that\u00a0<\/span><span data-contrast=\"auto\">pangolins may serve as SARS-CoV-2<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">intermediate hosts. Some of the observed variations in protein may serve as possible adaptation mutations in humans<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0but more studies are needed to\u00a0<\/span><span data-contrast=\"auto\">better understand<\/span><span data-contrast=\"auto\">\u00a0their function.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Bezerra et al. (May 29, 2020). The Novel Coronavirus SARS-CoV-2: From a Zoonotic Infection to Coronavirus Disease-19 (COVID19). Journal of Medical Virology.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1002\/jmv.26072\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1002\/jmv.26072<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7247\" class=\"su-post\">\n<h5 class=\"su-post-title\">Asymptomatic Transmission of SARS\u2010CoV\u20102 and Implications for Mass Gatherings<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Wong et al.\u00a0<\/span><span data-contrast=\"auto\">report<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">two further generations of SARS-CoV-2\u00a0<\/span><span data-contrast=\"auto\">transmission\u00a0<\/span><span data-contrast=\"auto\">from\u00a0<\/span><span data-contrast=\"auto\">attendees at a 16,000-person<\/span><span data-contrast=\"auto\">\u00a0event who remained asymptomatic<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">The investigation confirmed 19 cases of SARS-CoV-2 among attendees<\/span><span data-contrast=\"auto\">\u00a0and\u00a0<\/span><span data-contrast=\"auto\">52 cases among their secondary<\/span><span data-contrast=\"auto\">\u00a0contacts<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">The<\/span><span data-contrast=\"auto\">\u00a0authors argue for<\/span><span data-contrast=\"auto\">\u00a0widespread testing at mass gatherings in areas of known community transmission.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Wong et al. (May 30, 2020). Asymptomatic Transmission of SARS\u2010CoV\u20102 and Implications for Mass Gatherings. Influenza and Other Respiratory Viruses.<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1111\/irv.12767\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1111\/irv.12767<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7245\" class=\"su-post\">\n<h5 class=\"su-post-title\">Detectable Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Human Breast Milk of a Mildly Symptomatic Patient with Coronavirus Disease 2019 (COVID-19)<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Tam et al. reported a first case of detectable SARS-CoV-2 RNA from human milk in a\u00a0<\/span><span data-contrast=\"auto\">forty-year old\u00a0<\/span><span data-contrast=\"auto\">woman<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">with COVID-19. Despite mild clinical symptoms, this<\/span><span data-contrast=\"auto\">\u00a0patient\u00a0<\/span><span data-contrast=\"auto\">had detectable\u00a0<\/span><span data-contrast=\"auto\">viral RNA<\/span><span data-contrast=\"auto\">\u00a0in two separate samples\u00a0<\/span><span data-contrast=\"auto\">of\u00a0<\/span><span data-contrast=\"auto\">human<\/span><span data-contrast=\"auto\">\u00a0milk taken ten days apart<\/span><span data-contrast=\"auto\">, which were<\/span><span data-contrast=\"auto\">\u00a0interspersed with\u00a0a\u00a0<\/span><span data-contrast=\"auto\">several<\/span><span data-contrast=\"auto\">\u00a0negative results. The significance of this finding is uncertain as detectable RNA in these samples has not been shown to indicate viable virus nor to demonstrate a risk of infection via breastfeeding.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Tam et al. (June 1, 2020). Detectable Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Human Breast Milk of a Mildly Symptomatic Patient with Coronavirus Disease 2019 (COVID-19). Clinical Infectious Diseases.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa673\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1093\/cid\/ciaa673<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7243\" class=\"su-post\">\n<h5 class=\"su-post-title\">Small Droplet Aerosols in Poorly Ventilated Spaces and SARS-CoV-2 Transmission<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Somsen et al. use an\u00a0<\/span><span data-contrast=\"auto\">e<\/span><span data-contrast=\"auto\">xperimental system with healthy volunteers to examine the number, size, and persistence of respiratory droplets produced during a cough, sneeze, and normal talking. Small\u00a0<\/span><span data-contrast=\"auto\">droplets of the size potentially associated with aerosol transmission of SARS-CoV-2 persisted\u00a0up\u00a0to 9 minutes.\u00a0<\/span><span data-contrast=\"auto\">Increasing ventilation through mechanical systems and opening a door or a window substantially decreased the\u00a0<\/span><span data-contrast=\"auto\">persistence of droplets<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">These findings support improving ventilation for public spaces to clear potentially infectious aerosols<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Somsen et al. (May 27, 2020). Small Droplet Aerosols in Poorly Ventilated Spaces and SARS-CoV-2 Transmission.\u00a0The Lancet\u00a0Respiratory Medicine.<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1016\/S2213-2600(20)30245-9\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/S2213-2600(20)30245-9<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7241\" class=\"su-post\">\n<h5 class=\"su-post-title\">Estimation of the Basic Reproduction Number, Average Incubation Time, Asymptomatic Infection Rate, and Case Fatality Rate for COVID-19: Meta-Analysis and Sensitivity Analysis<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">He et al.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">performed a meta-analysis of<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">22 studies\u00a0<\/span><span data-contrast=\"auto\">that evaluate<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">measures of COVID-19\u00a0<\/span><span data-contrast=\"auto\">dynamics\u00a0<\/span><span data-contrast=\"auto\">and estimated the basic reproduction number<\/span><span data-contrast=\"auto\">\u00a0(R<\/span><span data-contrast=\"auto\">0<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">\u00a0to be 3.15 (95% CI 2.41, 3.90), the average incubation time to be 5.08 days (4.77, 5.39), the asymptomatic infection rate to be 46% (18.48%, 73.60%), and the case fatality rate to be 2.72% (1.29%, 4.16%) whe<\/span><span data-contrast=\"auto\">n<\/span><span data-contrast=\"auto\">\u00a0asymptomatic infections are\u00a0<\/span><span data-contrast=\"auto\">included<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">He et al. (May 29, 2020). Estimation of the Basic Reproduction Number, Average Incubation Time, Asymptomatic Infection Rate, and Case Fatality Rate for COVID-19: Meta-Analysis and Sensitivity Analysis. Journal of Medical Virology.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1002\/jmv.26041\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1002\/jmv.26041<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7239\" class=\"su-post\">\n<h5 class=\"su-post-title\">Surgical Mask Partition Reduces the Risk of Non-Contact Transmission in a Golden Syrian Hamster Model for Coronavirus Disease 2019 (COVID-19)<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">A hamster SARS-CoV-2 model experiment reported\u00a0<\/span><span data-contrast=\"auto\">the effect of adding a partition that simulates a surgical mask on<\/span><span data-contrast=\"auto\">\u00a0transmission between\u00a0<\/span><span data-contrast=\"auto\">hamste<\/span><span data-contrast=\"auto\">rs<\/span><span data-contrast=\"auto\">\u00a0in\u00a0<\/span><span data-contrast=\"auto\">separate<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">cages<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">with unidirectional airflow.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">In the absence of a mask partition, 67%<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">(10 of 15)\u00a0<\/span><span data-contrast=\"auto\">of exposed hamsters became infected. Adding the s<\/span><span data-contrast=\"auto\">urgical mask partition reduced transmission to\u00a0<\/span><span data-contrast=\"auto\">between\u00a0<\/span><span data-contrast=\"auto\">17 and\u00a0<\/span><span data-contrast=\"auto\">25%<\/span><span data-contrast=\"auto\">, depending on configuration<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Chan et al. (May 30, 2020). Surgical Mask Partition Reduces the Risk of Non-Contact Transmission in a Golden Syrian Hamster Model for Coronavirus Disease 2019 (COVID-19). Clinical Infectious Diseases<\/span><\/i><i><span data-contrast=\"none\">.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa644\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1093\/cid\/ciaa644<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Testing and Treatment<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7255\" class=\"su-post\">\n<h5 class=\"su-post-title\">Efficacy and Safety of Interferon Beta-1a in Treatment of Severe COVID-19 A Randomized Clinical Trial<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Davoudi-Monfared et al<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0report the results of a randomized trial<\/span><span data-contrast=\"auto\">\u00a0evaluating the efficacy and safety of\u00a0<\/span><span data-contrast=\"auto\">interferon<\/span><span data-contrast=\"auto\">\u00a0\u03b2-1a\u00a0<\/span><span data-contrast=\"auto\">(IFN)\u00a0<\/span><span data-contrast=\"auto\">in patients with severe COVID-19<\/span><span data-contrast=\"auto\">, which<\/span><span data-contrast=\"auto\">\u00a0showed no significant difference of time to clinical response between the IFN and the control groups (9.7\u00a0<\/span><span data-contrast=\"auto\">\u00b1<\/span><span data-contrast=\"auto\">\u00a05.8 vs. 8.3\u00a0<\/span><span data-contrast=\"auto\">\u00b1<\/span><span data-contrast=\"auto\">\u00a04.9 days).\u00a0<\/span><span data-contrast=\"auto\">The<\/span><span data-contrast=\"auto\">\u00a0IFN group had\u00a0<\/span><span data-contrast=\"auto\">a\u00a0<\/span><span data-contrast=\"auto\">higher discharge rate on day 14 and lower 28-day mortality (<\/span><span data-contrast=\"auto\">66.7% vs. 43.6%<\/span><span data-contrast=\"auto\">\u00a0and<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">19.0% vs. 38.5%<\/span><span data-contrast=\"auto\">, respectively<\/span><span data-contrast=\"auto\">).<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Davoudi-Monfared et al. (May 30, 2020). Efficacy and Safety of Interferon Beta-1a in Treatment of Severe COVID-19 A Randomized Clinical Trial. Pre-print\u00a0downloaded June 1 from<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1101\/2020.05.28.20116467\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.28.20116467<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7253\" class=\"su-post\">\n<h5 class=\"su-post-title\">Performance of Abbott ID NOW COVID-19 Rapid Nucleic Acid Amplification Test in Nasopharyngeal Swabs Transported in Viral Media and Dry Nasal Swabs, in a New York City Academic Institution<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Basu\u00a0et al.<\/span><span data-contrast=\"auto\">\u00a0evaluated\u00a0<\/span><span data-contrast=\"auto\">the performance of the\u00a0recently<\/span><span data-contrast=\"auto\">&#8211;<\/span><span data-contrast=\"auto\">released\u00a0Abbott ID NOW COVID-19 assay for SARS-CoV-2 RNA detection with the Cepheid Xpert Xpress SARS-CoV-2. They found that the ID NOW\u00a0<\/span><span data-contrast=\"auto\">assay\u00a0<\/span><span data-contrast=\"auto\">has utility as a rapid rule-in test for COVID-19 with samples at high viral load<\/span><span data-contrast=\"auto\">;<\/span><span data-contrast=\"auto\">\u00a0however, an overall low positive percent agreement (55%-67%) of ID NOW with Xpert Xpress raises concerns regarding its suitability as a diagnostic tool in samples with lower viral loads.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Basu\u00a0et al. (May\u00a0<\/span><\/i><i><span data-contrast=\"none\">29,\u00a0<\/span><\/i><i><span data-contrast=\"none\">2020). Performance of Abbott ID NOW COVID-19 Rapid Nucleic Acid Amplification Test in Nasopharyngeal Swabs Transported in Viral Media and Dry Nasal Swabs, in a New York City Academic Institution. Journal of Clinical Microbiology.<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1128\/JCM.01136-20\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1128\/JCM.01136-20<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\">Vaccines<\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7257\" class=\"su-post\">\n<h5 class=\"su-post-title\">How Efficacious Must a COVID-19 Coronavirus Vaccine Be to Prevent or Stop an Epidemic by Itself<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Bartsch et al.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">simulat<\/span><span data-contrast=\"auto\">ed<\/span><span data-contrast=\"auto\">\u00a0vaccination<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">strategies for SARS-CoV-2<\/span><span data-contrast=\"auto\">\u00a0in\u00a0<\/span><span data-contrast=\"auto\">the<\/span><span data-contrast=\"auto\">\u00a0US<\/span><span data-contrast=\"auto\">\u00a0and<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">concluded\u00a0<\/span><span data-contrast=\"auto\">that a vaccine with an efficacy\u00a0<\/span><span data-contrast=\"auto\">of at least<\/span><span data-contrast=\"auto\">\u00a070% and\u00a0<\/span><span data-contrast=\"auto\">coverage of at least 60<\/span><span data-contrast=\"auto\">% could\u00a0<\/span><span data-contrast=\"auto\">eliminate<\/span><span data-contrast=\"auto\">\u00a0the need for\u00a0<\/span><span data-contrast=\"auto\">social distancing<\/span><span data-contrast=\"auto\">\u00a0measures\u00a0<\/span><span data-contrast=\"auto\">if introduced within\u00a0<\/span><span data-contrast=\"auto\">90 days of\u00a0<\/span><span data-contrast=\"auto\">the\u00a0<\/span><span data-contrast=\"auto\">start of the pandemic<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Bartsch et al. (May 30, 2020). How Efficacious Must a COVID-19 Coronavirus Vaccine Be to Prevent or Stop an Epidemic by Itself. Pre-print\u00a0downloaded June 1 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.05.29.20117184\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.29.20117184<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Clinical Characteristics and Health Care Setting<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7259\" class=\"su-post\">\n<h5 class=\"su-post-title\">COVID-19 Mortality in Patients with Cancer on Chemotherapy or Other Anticancer Treatments:\u00a0A Prospective\u00a0Cohort Study<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Lee et al. report that a<\/span><span data-contrast=\"auto\">\u00a0multicenter observational study in\u00a0<\/span><span data-contrast=\"auto\">the<\/span><span data-contrast=\"auto\">\u00a0UK\u00a0<\/span><span data-contrast=\"auto\">found<\/span><span data-contrast=\"auto\">\u00a0no evidence that cancer patients\u00a0<\/span><span data-contrast=\"auto\">receiving<\/span><span data-contrast=\"auto\">\u00a0cytotoxic chemotherapy or other anticancer treatment\u00a0<\/span><span data-contrast=\"auto\">were<\/span><span data-contrast=\"auto\">\u00a0at an increased risk of mortality from COVID-19 compared\u00a0<\/span><span data-contrast=\"auto\">to<\/span><span data-contrast=\"auto\">\u00a0those not on active treatment.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">The<\/span><span data-contrast=\"auto\">\u00a0mortality\u00a0is principally driven by advancing age and non-cancer comorbidities.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">W<\/span><span data-contrast=\"auto\">ithholding effective cancer treatments during the pandemic\u00a0<\/span><span data-contrast=\"auto\">may\u00a0<\/span><span data-contrast=\"auto\">result in\u00a0<\/span><span data-contrast=\"auto\">increas<\/span><span data-contrast=\"auto\">ed<\/span><span data-contrast=\"auto\">\u00a0cancer morbidity and mortality<\/span><span data-contrast=\"auto\">\u00a0without preventing deaths from COVID-19<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Lee et al. (May 28, 2020). COVID-19 Mortality in Patients with Cancer on Chemotherapy or Other Anticancer Treatments:\u00a0A Prospective\u00a0Cohort Study. Lancet.<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(20)31173-9\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/S0140-6736(20)31173-9<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Modeling and Prediction<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7263\" class=\"su-post\">\n<h5 class=\"su-post-title\">Using Real-World Contact Networks to Quantify\u00a0the Effectiveness\u00a0of Digital Contact Tracing and Isolation Strategies for Covid-19 Pandemic<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Cencetti\u00a0et al. modeled contact tracing strategies and found that<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">imposing quarantine on contacts with longer exposures at a shorter distance minimized the social cost of quarantine. They found that additional measures needed to be implemented with\u00a0<\/span><span data-contrast=\"auto\">i<\/span><span data-contrast=\"auto\">solation and tracing\u00a0<\/span><span data-contrast=\"auto\">to control the outbreak, and that a\u00a0<\/span><span data-contrast=\"auto\">high level of app adoption\u00a0<\/span><span data-contrast=\"auto\">was\u00a0<\/span><span data-contrast=\"auto\">crucial to\u00a0<\/span><span data-contrast=\"auto\">effectiveness of\u00a0<\/span><span data-contrast=\"auto\">digital contact tracing.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Cencetti\u00a0et al. (May 30, 2020). Using Real-World Contact Networks to Quantify\u00a0<\/span><\/i><i><span data-contrast=\"none\">the Effectiveness<\/span><\/i><i><span data-contrast=\"none\">\u00a0of Digital Contact Tracing and Isolation Strategies for Covid-19 Pandemic. Pre-print\u00a0downloaded June 1 from<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1101\/2020.05.29.20115915\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.29.20115915<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7261\" class=\"su-post\">\n<h5 class=\"su-post-title\">The Effectiveness and Perceived Burden of Nonpharmaceutical Interventions against COVID-19 Transmission\u00a0a\u00a0Modelling Study with 41 Countries<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Brauner et al.\u00a0<\/span><span data-contrast=\"auto\">inferred the effectiveness of non-pharmaceutical interventions using data in 41 countries. Results suggest a surprisingly large role for schools in COVID-19 transmission<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">(mean reduction in R: 58%. Additional interventions with good effectiveness-burden tradeoffs include<\/span><span data-contrast=\"auto\">d<\/span><span data-contrast=\"auto\">\u00a0limiting gathering<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">, closing high-risk businesses, and testing<\/span><span data-contrast=\"auto\">\u00a0persons with symptoms.<\/span><span data-contrast=\"auto\">\u00a0Closing most nonessential businesses and issuing stay-at-home orders\u00a0<\/span><span data-contrast=\"auto\">were found to have<\/span><span data-contrast=\"auto\">\u00a0a limited additional effect<\/span><span data-contrast=\"auto\">\u00a0with a\u00a0high\u00a0perceived burden<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Brauner et al. (May 30, 2020). The Effectiveness and Perceived Burden of Nonpharmaceutical Interventions against COVID-19 Transmission\u00a0a\u00a0Modelling Study with 41 Countries. Pre-print\u00a0downloaded June 1 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.05.28.20116129\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.28.20116129<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<h3><strong>Other Resources and Commentaries<\/strong><\/h3>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/j.rbmo.2020.05.001\"><span data-contrast=\"none\">COVID-19 and fertility: a virtual reality<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">\u00a0Reproductive Biomedicine Online (<\/span><span data-contrast=\"auto\">May 10)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1136\/bmj.m2105\"><span data-contrast=\"none\">Care homes after covid-19: we need a wide ranging inquiry and reform<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 BMJ (<\/span><span data-contrast=\"auto\">May 28)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/j.ajem.2020.05.059\"><span data-contrast=\"none\">Critical medication shortages further dwindling hospital resources during COVID-19<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 The American Journal of Emergency Medicine (<\/span><span data-contrast=\"auto\">May 6)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/j.mbs.2020.108389\"><span data-contrast=\"none\">On the benefits of flattening the curve: A perspective<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Mathematical Biosciences<\/span><span data-contrast=\"auto\">\u00a0(May\u00a0<\/span><span data-contrast=\"auto\">27)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(20)31234-4\"><span data-contrast=\"none\">Excess mortality in men and women in Massachusetts during the COVID-19 pandemic<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">\u00a0Lancet\u00a0<\/span><br \/>\n<span data-contrast=\"auto\">(May<\/span><span data-contrast=\"auto\">\u00a027)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(20)31239-3\"><span data-contrast=\"none\">The starting line for COVID-19 vaccine development<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Lancet (May 2<\/span><span data-contrast=\"auto\">8<\/span><span data-contrast=\"auto\">)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1002\/jmv.26074\"><span data-contrast=\"none\">Recurrent positive SARS-CoV-2 &#8211; immune certificate may not be valid<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0<\/span><span data-contrast=\"auto\">Journal of Medical Virology (May 29)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1002\/jmv.26069\"><span data-contrast=\"none\">Higher prevalence of asymptomatic or mild COVID-19 in children, claims and clues<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Journal of Medical Virology (May 29)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/www.nature.com\/articles\/d41586-020-01578-0\"><span data-contrast=\"none\">Ethical guidelines for COVID-19 tracing apps<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Nature (<\/span><span data-contrast=\"auto\">May 28)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa692\"><span data-contrast=\"none\">COVID-19 outbreaks in U.S. immigrant detention centers: the urgent need to adopt CDC guidelines for prevention and evaluation<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Clinical Infectious Diseases<\/span><span data-contrast=\"auto\">\u00a0(May 31)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/S1473-3099(20)30435-7\"><span data-contrast=\"none\">Implication of SARS-CoV-2 evolution in the sensitivity of RT-qPCR diagnostic assays<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0The Lancet\u00a0<\/span><span data-contrast=\"auto\">Infectious Diseases (<\/span><span data-contrast=\"auto\">May 28)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa682\"><span data-contrast=\"none\">A Conceptual Discussion about R0 of SARS-COV-2 in Healthcare Settings<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Clinical Infectious Diseases<\/span><span data-contrast=\"auto\">\u00a0(May 30)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/j.idh.2020.05.002\"><span data-contrast=\"none\">SARS-CoV-2: The viral shedding vs infectivity dilemma<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Infection, Disease &amp; Health<\/span><span data-contrast=\"auto\">\u00a0(May 13)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.3390\/v12060582\"><span data-contrast=\"none\">Challenges in Laboratory Diagnosis of the Novel Coronavirus SARS-CoV-2<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Viruses\u00a0<\/span><span data-contrast=\"auto\">(May 26)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Better ventilation substantially reduces the amount of time respiratory droplets are airborne. This has potential implications for recommendations regarding avoidance of poorly ventilated public spaces and for hospitals to improve ventilation in settings where aerosolization by coughing and close contact with COVID-19 patients is common. <\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/01\/the-effectiveness-and-perceived-burden-of-nonpharmaceutical-interventions-against-covid-19-transmission-a-modelling-study-with-41-countries\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":341,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[5],"tags":[],"topic":[],"class_list":["post-7235","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19-literature-situation-report"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7235","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7235"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7235\/revisions"}],"predecessor-version":[{"id":7265,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7235\/revisions\/7265"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media\/341"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7235"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7235"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7235"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7235"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}