{"id":7249,"date":"2020-06-01T12:38:53","date_gmt":"2020-06-01T19:38:53","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7249"},"modified":"2021-03-24T12:39:45","modified_gmt":"2021-03-24T19:39:45","slug":"the-novel-coronavirus-sars-cov-2-from-a-zoonotic-infection-to-coronavirus-disease-19-covid19","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/01\/the-novel-coronavirus-sars-cov-2-from-a-zoonotic-infection-to-coronavirus-disease-19-covid19\/","title":{"rendered":"The Novel Coronavirus SARS-CoV-2: From a Zoonotic Infection to Coronavirus Disease-19 (COVID19)"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">A phylogenetic analysis reconstructed from\u00a0CoV\u00a0strains demonstrated that SARS-CoV-2, bat RaTG13 and pangolin\u00a0CoV\u00a0genomes formed a cluster, suggesting\u00a0<\/span><span data-contrast=\"auto\">a close<\/span><span data-contrast=\"auto\">\u00a0relationship between SARS-CoV-2 and bat SARS-like strains, and\u00a0<\/span><span data-contrast=\"auto\">that\u00a0<\/span><span data-contrast=\"auto\">pangolins may serve as SARS-CoV-2<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">intermediate hosts. Some of the observed variations in protein may serve as possible adaptation mutations in humans<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0but more studies are needed to\u00a0<\/span><span data-contrast=\"auto\">better understand<\/span><span data-contrast=\"auto\">\u00a0their function.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Bezerra et al. (May 29, 2020). The Novel Coronavirus SARS-CoV-2: From a Zoonotic Infection to Coronavirus Disease-19 (COVID19). Journal of Medical Virology.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1002\/jmv.26072\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1002\/jmv.26072<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A phylogenetic analysis reconstructed from\u00a0CoV\u00a0strains demonstrated that SARS-CoV-2, bat RaTG13 and pangolin\u00a0CoV\u00a0genomes formed a cluster, suggesting\u00a0a close\u00a0relationship between SARS-CoV-2 and bat SARS-like strains, and\u00a0that\u00a0pangolins may serve as SARS-CoV-2\u00a0intermediate hosts. Some of the observed variations in protein may serve as possible adaptation mutations in humans,\u00a0but more studies are needed to\u00a0better understand\u00a0their function.\u00a0\u00a0 Bezerra et al. (May&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/01\/the-novel-coronavirus-sars-cov-2-from-a-zoonotic-infection-to-coronavirus-disease-19-covid19\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[21],"class_list":["post-7249","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-transmission"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7249","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7249"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7249\/revisions"}],"predecessor-version":[{"id":7250,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7249\/revisions\/7250"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7249"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7249"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7249"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7249"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}