{"id":7276,"date":"2020-06-02T12:52:58","date_gmt":"2020-06-02T19:52:58","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7276"},"modified":"2021-03-24T12:53:39","modified_gmt":"2021-03-24T19:53:39","slug":"pathogenesis-transmission-and-response-to-re-exposure-of-sars-cov-2-in-domestic-cats","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/02\/pathogenesis-transmission-and-response-to-re-exposure-of-sars-cov-2-in-domestic-cats\/","title":{"rendered":"Pathogenesis Transmission and Response to Re-Exposure of SARS-CoV-2 in Domestic Cats"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Bosco-Lauth et al<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">show<\/span><span data-contrast=\"auto\">ed<\/span><span data-contrast=\"auto\">\u00a0that cats are susceptible to subclinical infection\u00a0<\/span><span data-contrast=\"auto\">with\u00a0<\/span><span data-contrast=\"auto\">SARS-CoV-2, capable of direct transmission to other cats, have prolonged viral shedding for up to 5 days, and develop a neutralizing antibody response that\u00a0<\/span><span data-contrast=\"auto\">prevents\u00a0<\/span><span data-contrast=\"auto\">reinfection. Dogs also developed an antibody response but were found to not shed the virus after infection.\u00a0<\/span><span data-contrast=\"auto\">None of the\u00a0<\/span><span data-contrast=\"auto\">animals exhibit<\/span><span data-contrast=\"auto\">ed<\/span><span data-contrast=\"auto\">\u00a0any clinical signs of disease during\u00a0the\u00a0study.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">The authors conclude that t<\/span><span data-contrast=\"auto\">hese results suggest that it<\/span><span data-contrast=\"auto\">\u00a0is<\/span><span data-contrast=\"auto\">\u00a0unlikely that domestic pets can be a significant source of infection, and\u00a0<\/span><span data-contrast=\"auto\">that\u00a0<\/span><span data-contrast=\"auto\">neutralizing antibody titers may have implications\u00a0<\/span><span data-contrast=\"auto\">for\u00a0<\/span><span data-contrast=\"auto\">vaccine development for humans<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Bosco-Lauth et al. (June 1, 2020). Pathogenesis Transmission and Response to Re-Exposure of SARS-CoV-2 in Domestic Cats.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Preprint\u00a0downloaded\u00a0June\u00a02 from<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.05.28.120998\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.05.28.120998<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[pre-print, not peer reviewed]\u00a0Bosco-Lauth et al.\u00a0showed\u00a0that cats are susceptible to subclinical infection\u00a0with\u00a0SARS-CoV-2, capable of direct transmission to other cats, have prolonged viral shedding for up to 5 days, and develop a neutralizing antibody response that\u00a0prevents\u00a0reinfection. Dogs also developed an antibody response but were found to not shed the virus after infection.\u00a0None of the\u00a0animals exhibited\u00a0any clinical&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/02\/pathogenesis-transmission-and-response-to-re-exposure-of-sars-cov-2-in-domestic-cats\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[21],"class_list":["post-7276","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-transmission"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7276","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7276"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7276\/revisions"}],"predecessor-version":[{"id":7277,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7276\/revisions\/7277"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7276"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7276"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7276"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7276"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}