{"id":7286,"date":"2020-06-02T12:57:32","date_gmt":"2020-06-02T19:57:32","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7286"},"modified":"2021-03-24T12:58:13","modified_gmt":"2021-03-24T19:58:13","slug":"profiling-serum-cytokines-in-covid-19-patients-reveals-il-6-and-il-10-are-disease-severity-predictors","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/02\/profiling-serum-cytokines-in-covid-19-patients-reveals-il-6-and-il-10-are-disease-severity-predictors\/","title":{"rendered":"Profiling Serum Cytokines in COVID-19 Patients Reveals IL-6 and IL-10 Are Disease Severity Predictors"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Han et al. found<\/span><span data-contrast=\"auto\">\u00a0that levels of cytokines and C-<\/span><span data-contrast=\"auto\">r<\/span><span data-contrast=\"auto\">eactive\u00a0<\/span><span data-contrast=\"auto\">p<\/span><span data-contrast=\"auto\">rotein were higher<\/span><span data-contrast=\"auto\">\u00a0in serum samples<\/span><span data-contrast=\"auto\">\u00a0from COVID-19 patients<\/span><span data-contrast=\"auto\">\u00a0(n=102)<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">than\u00a0<\/span><span data-contrast=\"auto\">control samples from healthy volunteers (n=45). Within COVID-19 patients, IL-6 and IL-10 levels were significantly higher in the critical\u00a0<\/span><span data-contrast=\"auto\">group, indicating that higher levels of cytokine\u00a0storm\u00a0are associated with more severe disease development.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Han et al. (May 31, 2020). Profiling Serum Cytokines in COVID-19 Patients Reveals IL-6 and IL-10 Are Disease Severity Predictors. Emerging Microbes &amp; Infections.<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1080\/22221751.2020.1770129\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1080\/22221751.2020.1770129<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Han et al. found\u00a0that levels of cytokines and C-reactive\u00a0protein were higher\u00a0in serum samples\u00a0from COVID-19 patients\u00a0(n=102)\u00a0than\u00a0control samples from healthy volunteers (n=45). Within COVID-19 patients, IL-6 and IL-10 levels were significantly higher in the critical\u00a0group, indicating that higher levels of cytokine\u00a0storm\u00a0are associated with more severe disease development.\u00a0 Han et al. (May 31, 2020). Profiling Serum Cytokines in&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/02\/profiling-serum-cytokines-in-covid-19-patients-reveals-il-6-and-il-10-are-disease-severity-predictors\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-7286","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7286","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7286"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7286\/revisions"}],"predecessor-version":[{"id":7287,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7286\/revisions\/7287"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7286"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7286"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7286"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7286"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}