{"id":7313,"date":"2020-06-03T13:11:52","date_gmt":"2020-06-03T20:11:52","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7313"},"modified":"2021-03-24T13:12:36","modified_gmt":"2021-03-24T20:12:36","slug":"ace-inhibitors-and-angiotensin-2-receptor-blockers-are-not-associated-with-severe-sars-covid19-infection-in-a-multi-site-uk-acute-hospital-trust","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/03\/ace-inhibitors-and-angiotensin-2-receptor-blockers-are-not-associated-with-severe-sars-covid19-infection-in-a-multi-site-uk-acute-hospital-trust\/","title":{"rendered":"ACE-Inhibitors and Angiotensin-2 Receptor Blockers Are Not\u00a0Associated with Severe SARS-COVID19 Infection in a Multi-Site UK Acute Hospital Trust"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">It has been hypothesized that ACE-inhibitors and\u00a0<\/span><span data-contrast=\"auto\">a<\/span><span data-contrast=\"auto\">ngiotensin<\/span><span data-contrast=\"auto\">-2\u00a0<\/span><span data-contrast=\"auto\">b<\/span><span data-contrast=\"auto\">lockers<\/span><span data-contrast=\"auto\">, medications commonly prescribed to patients with hypertension or diabetes,\u00a0<\/span><span data-contrast=\"auto\">could\u00a0<\/span><span data-contrast=\"auto\">increase the risk of severe COVID-19 infection\u00a0<\/span><span data-contrast=\"auto\">by increasing the number of ACE2 receptors that<\/span><span data-contrast=\"auto\">\u00a0SARS-<\/span><span data-contrast=\"auto\">Co<\/span><span data-contrast=\"auto\">V<\/span><span data-contrast=\"auto\">-2\u00a0<\/span><span data-contrast=\"auto\">uses\u00a0<\/span><span data-contrast=\"auto\">for cell entry. However, Bean et al. found no evidence for increased risk of ICU admission or death\u00a0<\/span><span data-contrast=\"auto\">associated with these medications\u00a0<\/span><span data-contrast=\"auto\">in a cohort of 1,200 hospitalized COVID-19 patients.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Bean et al. (June 2, 2020). ACE-Inhibitors and Angiotensin-2 Receptor Blockers Are Not\u00a0<\/span><\/i><i><span data-contrast=\"none\">Associated with Severe SARS-COVID19 Infection in a Multi-Site UK Acute Hospital Trust. European Journal of Heart Failure.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1002\/ejhf.1924\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1002\/ejhf.1924<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>It has been hypothesized that ACE-inhibitors and\u00a0angiotensin-2\u00a0blockers, medications commonly prescribed to patients with hypertension or diabetes,\u00a0could\u00a0increase the risk of severe COVID-19 infection\u00a0by increasing the number of ACE2 receptors that\u00a0SARS-CoV-2\u00a0uses\u00a0for cell entry. However, Bean et al. found no evidence for increased risk of ICU admission or death\u00a0associated with these medications\u00a0in a cohort of 1,200 hospitalized COVID-19&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/03\/ace-inhibitors-and-angiotensin-2-receptor-blockers-are-not-associated-with-severe-sars-covid19-infection-in-a-multi-site-uk-acute-hospital-trust\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-7313","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7313","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7313"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7313\/revisions"}],"predecessor-version":[{"id":7314,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7313\/revisions\/7314"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7313"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7313"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7313"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7313"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}