{"id":738,"date":"2020-09-04T17:14:45","date_gmt":"2020-09-05T00:14:45","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=738"},"modified":"2020-09-09T17:15:35","modified_gmt":"2020-09-10T00:15:35","slug":"chloroquine-and-hydroxychloroquine-for-the-treatment-of-covid-19-a-systematic-review-and-meta-analysis","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/04\/chloroquine-and-hydroxychloroquine-for-the-treatment-of-covid-19-a-systematic-review-and-meta-analysis\/","title":{"rendered":"Chloroquine and Hydroxychloroquine for the Treatment of COVID-19: A Systematic Review and Meta-Analysis"},"content":{"rendered":"<ul>\n<li>A meta-analysis of 12 observational and 3 randomized trials found that the efficacy of chloroquine and hydroxychloroquine was inconsistent across the studies. There was no significant reduction in mortality with hydroxychloroquine use (RR=0.98, 95% CI: 0.66-1.46), and there was a higher risk of ECG abnormalities \/arrhythmia associated with hydroxychloroquine\/chloroquine use (RR=1.46, 95% CI: 1.04-2.06).<\/li>\n<\/ul>\n<p><em>Elavarasi et al. (Sept 3, 2020). Chloroquine and Hydroxychloroquine for the Treatment of COVID-19: A Systematic Review and Meta-Analysis. Journal of General Internal Medicine. <a href=\"https:\/\/doi.org\/10.1007\/s11606-020-06146-w\">https:\/\/doi.org\/10.1007\/s11606-020-06146-w<\/a><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A meta-analysis of 12 observational and 3 randomized trials found that the efficacy of chloroquine and hydroxychloroquine was inconsistent across the studies. There was no significant reduction in mortality with hydroxychloroquine use (RR=0.98, 95% CI: 0.66-1.46), and there was a higher risk of ECG abnormalities \/arrhythmia associated with hydroxychloroquine\/chloroquine use (RR=1.46, 95% CI: 1.04-2.06). Elavarasi&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/04\/chloroquine-and-hydroxychloroquine-for-the-treatment-of-covid-19-a-systematic-review-and-meta-analysis\/\">Read more<\/a><\/div>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[28],"topic":[19],"class_list":["post-738","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-treatment","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/738","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=738"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/738\/revisions"}],"predecessor-version":[{"id":739,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/738\/revisions\/739"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=738"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=738"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=738"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=738"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}