{"id":7388,"date":"2020-06-08T15:35:33","date_gmt":"2020-06-08T22:35:33","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7388"},"modified":"2021-03-24T15:54:00","modified_gmt":"2021-03-24T22:54:00","slug":"covid-19-literature-situation-report-june-8-2020","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/08\/covid-19-literature-situation-report-june-8-2020\/","title":{"rendered":"COVID-19 Literature Situation Report June 8, 2020"},"content":{"rendered":"<p>The scientific literature on COVID-19 is rapidly evolving and these articles were selected for review based on their relevance to Washington State decision making around COVID-19 response efforts. Included in these Lit Reps are some manuscripts that have been made available online as pre-prints but have not yet undergone peer review. Please be aware of this when reviewing articles included in the Lit Reps.<\/p>\n<h2>Key Takeaways<\/h2>\n<ul>\n<li><b><span data-contrast=\"auto\">Stay-at-home orders were associated with decreases in\u00a0<\/span><\/b><b><span data-contrast=\"auto\">reports of\u00a0<\/span><\/b><b><span data-contrast=\"auto\">robberies and traffic stops and increases in domestic violence calls in\u00a0<\/span><\/b><b><span data-contrast=\"auto\">Los Angeles\u00a0<\/span><\/b><b><span data-contrast=\"auto\">and Indianapolis<\/span><\/b><b><span data-contrast=\"auto\">.<\/span><\/b><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">The addition of high-dose\u00a0<\/span><\/b><b><span data-contrast=\"auto\">intravenous\u00a0<\/span><\/b><b><span data-contrast=\"auto\">anakinra\u00a0<\/span><\/b><b><span data-contrast=\"auto\">[<\/span><\/b><b><span data-contrast=\"auto\">a<\/span><\/b><b><span data-contrast=\"auto\">n interleukin (IL)-1 receptor<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">blocker<\/span><\/b><b><span data-contrast=\"auto\">]<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">to standard of care for patients with severe COVID-19 was associated with a higher probability of survival<\/span><\/b><b><span data-contrast=\"auto\">.<\/span><\/b><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">SARS-CoV-2\u00a0<\/span><\/b><b><span data-contrast=\"auto\">seropositivity\u00a0<\/span><\/b><b><span data-contrast=\"auto\">was\u00a0<\/span><\/b><b><span data-contrast=\"auto\">3-4% among heath care workers and\u00a0<\/span><\/b><b><span data-contrast=\"auto\">their relatives\u00a0<\/span><\/b><b><span data-contrast=\"auto\">in Wuhan, China and lower\u00a0<\/span><\/b><b><span data-contrast=\"auto\">among\u00a0<\/span><\/b><b><span data-contrast=\"auto\">health care workers and patients\u00a0<\/span><\/b><b><span data-contrast=\"auto\">in\u00a0<\/span><\/b><b><span data-contrast=\"auto\">other\u00a0<\/span><\/b><b><span data-contrast=\"auto\">cities\u00a0<\/span><\/b><b><span data-contrast=\"auto\">in<\/span><\/b><b><span data-contrast=\"auto\">\u00a0Hubei province<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">further<\/span><\/b><b><span data-contrast=\"auto\">\u00a0from Wuhan<\/span><\/b><b><span data-contrast=\"auto\">.<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"3\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">Specificity was found to be high for three commercial\u00a0<\/span><\/b><b><span data-contrast=\"auto\">SARS-CoV-2\u00a0<\/span><\/b><b><span data-contrast=\"auto\">antibody tests, but\u00a0<\/span><\/b><b><span data-contrast=\"auto\">still\u00a0<\/span><\/b><b><span data-contrast=\"auto\">in<\/span><\/b><b><span data-contrast=\"auto\">sufficient\u00a0<\/span><\/b><b><span data-contrast=\"auto\">t<\/span><\/b><b><span data-contrast=\"auto\">o\u00a0<\/span><\/b><b><span data-contrast=\"auto\">yield a high positive predictive value in\u00a0<\/span><\/b><b><span data-contrast=\"auto\">low seroprevalence<\/span><\/b><b><span data-contrast=\"auto\">\u00a0settings.<\/span><\/b><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<div id=\"uw-accordion-shortcode\">\n<h3>Article Summaries<\/h3>\n<div class=\"js-accordion\" data-accordion-prefix-classes=\"uw-accordion-shortcode\">\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Non-Pharmaceutical Interventions<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7392\" class=\"su-post\">\n<h5 class=\"su-post-title\">COVID-19 and Non-Traditional Mask Use: How Do Various Materials Compare in Reducing the Infection Risk for Mask Wearers?<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Wilson et al. found that mask use reduced mean infection risk by 44-99% for short exposures and 24-94% for long exposures u<\/span><span data-contrast=\"auto\">sing a probabilistic model\u00a0<\/span><span data-contrast=\"auto\">with<\/span><span data-contrast=\"auto\">\u00a0exposure scenarios\u00a0<\/span><span data-contrast=\"auto\">that represented\u00a0<\/span><span data-contrast=\"auto\">a healthcare setting<\/span><span data-contrast=\"auto\">. Of non-traditional materials<\/span><span data-contrast=\"auto\">\u00a0that could be used for masks<\/span><span data-contrast=\"auto\">, vacuum cleaner bags were the most effective, and scarves were the least effective.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Wilson et al. (June 2, 2020). COVID-19 and Non-Traditional Mask Use: How Do Various Materials Compare in Reducing the Infection Risk for Mask Wearers? The Journal of Hospital Infection.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.jhin.2020.05.036\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.jhin.2020.05.036<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7390\" class=\"su-post\">\n<h5 class=\"su-post-title\">Impact of Social Distancing\u00a0during COVID-19 Pandemic on Crime in Los Angeles and Indianapolis<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"40\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">After stay-at-home orders were implemented,\u00a0<\/span><span data-contrast=\"auto\">police\u00a0<\/span><span data-contrast=\"auto\">calls-for-service for\u00a0<\/span><span data-contrast=\"auto\">burglary\u00a0<\/span><span data-contrast=\"auto\">and robbery<\/span><span data-contrast=\"auto\">\u00a0decreased<\/span><span data-contrast=\"auto\">\u00a0in\u00a0<\/span><span data-contrast=\"auto\">Los Angeles<\/span><span data-contrast=\"auto\">, CA<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">and calls for domestic violence and\u00a0<\/span><span data-contrast=\"auto\">vehicle theft increased. A similar pattern was observed in<\/span><span data-contrast=\"auto\">\u00a0Indianapolis,\u00a0<\/span><span data-contrast=\"auto\">IN for robbery and domestic violence calls<\/span><span data-contrast=\"auto\">. Traffic stops were also markedly decreased in both cities.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Mohler et al. (May 2020). Impact of Social Distancing\u00a0<\/span><\/i><i><span data-contrast=\"none\">during COVID-19 Pandemic on Crime in Los Angeles and Indianapolis. Journal of Criminal Justice.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.jcrimjus.2020.101692\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.jcrimjus.2020.101692<\/span><\/i><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Transmission<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7394\" class=\"su-post\">\n<h5 class=\"su-post-title\">Seroprevalence of Immunoglobulin M and G Antibodies against SARS-CoV-2 in China<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"39\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Seroprevalence of\u00a0<\/span><span data-contrast=\"auto\">antibodies against SARS-CoV-2<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">was 4% among healthcare workers and 3% among their families<\/span><span data-contrast=\"auto\">\u00a0in the city of Wuhan<\/span><span data-contrast=\"auto\">, China<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">between March 9 and April 10<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0In<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">other\u00a0<\/span><span data-contrast=\"auto\">cities in Hubei province,\u00a0<\/span><span data-contrast=\"auto\">seropositivity<\/span><span data-contrast=\"auto\">\u00a0was\u00a0<\/span><span data-contrast=\"auto\">lower\u00a0<\/span><span data-contrast=\"auto\">in cities that were further<\/span><span data-contrast=\"auto\">\u00a0from Wuhan. While\u00a0<\/span><span data-contrast=\"auto\">seropositivity<\/span><span data-contrast=\"auto\">\u00a0was\u00a0<\/span><span data-contrast=\"auto\">highest for IgG, some individuals were positive\u00a0<\/span><span data-contrast=\"auto\">only for<\/span><span data-contrast=\"auto\">\u00a0IgM, underscoring that\u00a0<\/span><span data-contrast=\"auto\">testing for both antibody types may be necessary in\u00a0<\/span><span data-contrast=\"auto\">seroprevalence studies.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:240}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Xu et al. (June 5, 2020). Seroprevalence of Immunoglobulin M and G Antibodies against SARS-CoV-2 in China. Nature Medicine.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1038\/s41591-020-0949-6\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1038\/s41591-020-0949-6<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:1080,&quot;335559739&quot;:160,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Testing and Treatment<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7402\" class=\"su-post\">\n<h5 class=\"su-post-title\">Detection of SARS-CoV-2 Antibodies Using Commercial Assays and Seroconversion Patterns in Hospitalized Patients<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"36\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Tuaillon\u00a0et al.\u00a0<\/span><span data-contrast=\"auto\">evaluated\u00a0<\/span><span data-contrast=\"auto\">six point-of-care (POC) and three ELISA tests to\u00a0<\/span><span data-contrast=\"auto\">determine their sensitivity and specificity for the detection of SARS-CoV-2 antibodies between 1 day and\u00a0<\/span><span data-contrast=\"auto\">&gt;<\/span><span data-contrast=\"auto\">15 days after onset of symptoms.\u00a0<\/span><span data-contrast=\"auto\">Most tests detected antibodies in at least 50% of samples by day 7 and nearly all tests were positive for &gt;80% of samples after 15 days, although none of the tests were positive for 100% of the samples.\u00a0<\/span><span data-contrast=\"auto\">Three<\/span><span data-contrast=\"auto\">\u00a0assays had a specificity of less than 90%.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Tuaillon\u00a0et al. (June 2020). Detection of SARS-CoV-2 Antibodies Usi<\/span><\/i><i><span data-contrast=\"none\">ng Commercial Assays and Seroconversion Patterns in Hospitalized Patients. The Journal of Infection.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.jinf.2020.05.077\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.jinf.2020.05.077<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7400\" class=\"su-post\">\n<h5 class=\"su-post-title\">Identification of Nsp1 Gene as the Target of SARS-CoV-2 Real-Time RT-PCR Using Nanopore Whole Genome Sequencing<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"36\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Chan et al. found that\u00a0<\/span><span data-contrast=\"auto\">SARS-CoV-2 mutations in current binding sites for PCR tests may compromise their sensitivity\u00a0<\/span><span data-contrast=\"auto\">and<\/span><span data-contrast=\"auto\">\u00a0identified the nsp1 gene as a novel target. An RT-PCR assay developed using this\u00a0<\/span><span data-contrast=\"auto\">target<\/span><span data-contrast=\"auto\">\u00a0had a sensitivity of 93.1% and a specificity of 100%.\u00a0\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Chan et al. (June 202<\/span><\/i><i><span data-contrast=\"none\">0). Identification of Nsp1 Gene as the Target of SARS-CoV-2 Real-Time RT-PCR Using Nanopore Whole Genome Sequencing. Journal of Medical Virology.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1002\/jmv.26140\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1002\/jmv.26140<\/span><\/i><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7398\" class=\"su-post\">\n<h5 class=\"su-post-title\">Side by Side Comparison of Three Fully Automated SARS-CoV-2 Antibody Assays with a Focus on Specificity<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"36\" data-aria-posinset=\"2\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Comparison of the Abbott, Roche, and DiaSorin antibody assays found high specificity for all three (ranging from 98.3% to 99.2%). However, when seroprevalence is low, even these high specificities can result in very low positive predictive values (32.6% to 77.6% at 1% prevalence). Sensitivity was found to be lower than reported by the manufacturers (ranging from 83.1% to 89.2%) and the Roche and DiaSorin tests were most likely to disagree with each other.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Perkmann\u00a0et al. (June 5, 2020). Side by Side Com<\/span><\/i><i><span data-contrast=\"none\">parison of Three Fully Automated SARS-CoV-2 Antibody Assays with a Focus on Specificity.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print\u00a0downloaded\u00a0June\u00a0<\/span><\/i><i><span data-contrast=\"none\">8<\/span><\/i><i><span data-contrast=\"none\">\u00a0from<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.06.04.20117911\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.06.04.20117911<\/span><\/i><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7396\" class=\"su-post\">\n<h5 class=\"su-post-title\">Interleukin-1 Blockade with High-Dose Anakinra in Patients with COVID-19, Acute Respiratory Distress Syndrome, and Hyperinflammation:\u00a0A Retrospective\u00a0Cohort Study<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"36\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Cavalli et al. observed that patients (n=29) who received a high-dose of intravenous anakinra (an interleukin (IL)-1 receptor blocker) had a higher probability of survival at 21 days among a cohort of patients with COVID-19 who had moderate-to-severe ARDS and hyperinflammation and who were managed with non-invasive ventilation outside of the ICU. Treated patients were compared to patients who received standard-of-care at the time (hydroxychloroquine and lopinavir\/ritonavir).\u00a0Probability\u00a0of bacteremia was nearly equivalent in the two groups. Low-dose subcutaneous anakinra had no appreciable effects on clinical status or biomarkers.\u00a0\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Cavalli et al. (June 2020). Interleukin-1 Blockade with High-Dose Anakinra in Patients with COVID-19, Acute Respiratory Distress Syndrome, and Hyperinflammation:\u00a0A Retrospective\u00a0Cohort Study.\u00a0The Lancet\u00a0Rheumatology.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/S2665-9913(20)30127-2\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/S2665-9913(20)30127-2<\/span><\/i><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Clinical Characteristics and Health Care Setting<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7408\" class=\"su-post\">\n<h5 class=\"su-post-title\">Association Between Mode of Delivery Among Pregnant Women With COVID-19 and Maternal and Neonatal Outcomes in Spain<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"36\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Severe\u00a0<\/span><span data-contrast=\"auto\">adverse maternal outcomes occurred in\u00a0<\/span><span data-contrast=\"auto\">9\/82 (<\/span><span data-contrast=\"auto\">11%<\/span><span data-contrast=\"auto\">) pregnant women\u00a0<\/span><span data-contrast=\"auto\">who tested positive for SARS-CoV-2 in a Spanish cohort. Four of the 9\u00a0<\/span><span data-contrast=\"auto\">had mild COVID-19 symptoms<\/span><span data-contrast=\"auto\">\u00a0and 5\/9 had severe symptoms<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"36\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Women\u00a0<\/span><span data-contrast=\"auto\">who delivered by<\/span><span data-contrast=\"auto\">\u00a0cesarean sections (necessitated by COVID-19 symptoms in 100% of those with severe symptoms and 10% of those with mild symptoms)<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">were<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">more likely to require ICU admission and experience clinical deterioration than those with vaginal delivery and their newborns were more likely to be admitted to the NICU<\/span><span data-contrast=\"auto\">;\u00a0<\/span><span data-contrast=\"auto\">however\u00a0this study\u00a0<\/span><span data-contrast=\"auto\">did\u00a0<\/span><span data-contrast=\"auto\">not include mother-infant dyads undergoing cesarean section in the absence of maternal COVID-19 infection.\u00a0<\/span><span data-contrast=\"auto\">Five infants eventually tested positive for SARS-CoV-2 and two developed COVID-19 symptoms, which\u00a0resolved\u00a0<\/span><span data-contrast=\"auto\">after<\/span><span data-contrast=\"auto\">\u00a048 hours.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Mart\u00ednez-Perez et al. (June 8, 2020). Association Between Mode of Delivery Among Pregnant Women With COVID-19 and Maternal and Neonatal Outcomes in Spain. JAMA.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jama.2020.10125\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jama.2020.10125<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7406\" class=\"su-post\">\n<h5 class=\"su-post-title\">Clinical Characteristics of 58 Children\u00a0With\u00a0a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"36\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Whittaker et al. compare<\/span><span data-contrast=\"auto\">d<\/span><span data-contrast=\"auto\">\u00a0the features of\u00a0<\/span><span data-contrast=\"auto\">pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2<\/span><span data-contrast=\"auto\">\u00a0infection<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">(PIMS-TS)\u00a0<\/span><span data-contrast=\"auto\">to that of Kawasaki Disease (KD) and KD shock syndrome. Of 58 PIMS-TS patients,<\/span><span data-contrast=\"auto\">\u00a078% had evidence of current or prior SARS-CoV-2 infection. Fifty percent developed shock, 22%\u00a0<\/span><span data-contrast=\"auto\">met the definition for\u00a0<\/span><span data-contrast=\"auto\">KD<\/span><span data-contrast=\"auto\">,\u00a0<\/span><span data-contrast=\"auto\">and 14% developed coronary artery dilatation or aneurysm. Compared with\u00a0<\/span><span data-contrast=\"auto\">other cases of\u00a0<\/span><span data-contrast=\"auto\">KD and KD shock synd<\/span><span data-contrast=\"auto\">rome<\/span><span data-contrast=\"auto\">, PIMS-TS cases were older and had<\/span><span data-contrast=\"auto\">\u00a0higher<\/span><span data-contrast=\"auto\">\u00a0levels of inflammatory biomarkers.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Whittaker et al. (June 8, 2020). Clinical Characteristics of 58 Children\u00a0With\u00a0a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2. JAMA.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jama.2020.10369\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jama.2020.10369<\/span><\/i><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7404\" class=\"su-post\">\n<h5 class=\"su-post-title\">Cardiovascular Complications in COVID-19:\u00a0A Systematic\u00a0Review and Meta-Analysis<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"36\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">A systematic review and meta-analysis found\u00a0<\/span><span data-contrast=\"auto\">that\u00a0<\/span><span data-contrast=\"auto\">the incidence of cardiovascular complications among patients with COVID-19<\/span><span data-contrast=\"auto\">\u00a0was highest for heart failure, myocardial injury, and cardiac arrhythmias<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">I<\/span><span data-contrast=\"auto\">ncidence\u00a0<\/span><span data-contrast=\"auto\">of myocardial injury was higher in older age groups<\/span><span data-contrast=\"auto\">\u00a0and\u00a0<\/span><span data-contrast=\"auto\">groups with a higher<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">prevalence of pre-existing\u00a0hypertension, but\u00a0did not differ\u00a0<\/span><span data-contrast=\"auto\">substantially<\/span><span data-contrast=\"auto\">\u00a0between those with and without pre-existing cardiovascular disease.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Kunutsor\u00a0and Laukkanen. (June 3, 2020). Cardiovascular Complications in COVID-19:\u00a0A Systematic\u00a0Review and Meta-Analysis. The Journal of Infection.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.jinf.2020.05.068\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.jinf.2020.05.068<\/span><\/i><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Modeling and Prediction<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7410\" class=\"su-post\">\n<h5 class=\"su-post-title\">Effects of Non-Pharmaceutical Interventions on COVID-19 Cases, Deaths, and Demand for Hospital Services in the UK: A Modelling Study<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"36\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Davies et al. used a\u00a0<\/span><span data-contrast=\"auto\">transmission model\u00a0<\/span><span data-contrast=\"auto\">to\u00a0<\/span><span data-contrast=\"auto\">estimate\u00a0<\/span><span data-contrast=\"auto\">that\u00a0<\/span><span data-contrast=\"auto\">without mitigation measures\u00a0<\/span><span data-contrast=\"auto\">23 million cases and 350,000 deaths due to COVID-19\u00a0<\/span><span data-contrast=\"auto\">would occur\u00a0<\/span><span data-contrast=\"auto\">in the UK by\u00a0December,\u00a02021. School closures, physical distancing, shielding people aged 70 or older, and isolation of symptomatic cases, in combination,\u00a0<\/span><span data-contrast=\"auto\">was projected to\u00a0<\/span><span data-contrast=\"auto\">reduce<\/span><span data-contrast=\"auto\">\u00a0cases and deaths,<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">but r<\/span><span data-contrast=\"auto\">epeated periods of phased lockdown<\/span><span data-contrast=\"auto\">s\u00a0<\/span><span data-contrast=\"auto\">would need to be in place for a large proportion of the coming year to prevent healthcare demand from exceeding capacity.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Davies et al. (June 2020). Effects of Non-Pharmaceutical Interventions on COVID-19 Cases, Deaths, and Demand for Hospital Services in the UK: A M<\/span><\/i><i><span data-contrast=\"none\">odelling Study.\u00a0The Lancet<\/span><\/i><i><span data-contrast=\"none\">\u00a0Public Health.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/S2468-2667(20)30133-X\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/S2468-2667(20)30133-X<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<h3><strong>Other Resources and Commentaries<\/strong><\/h3>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa735\"><span data-contrast=\"none\">C<\/span><span data-contrast=\"none\">an the SARS-CoV-2 PCR Cycle Threshold Value and Time from Symptom Onset to Testing Predict Infectivity?<\/span><\/a><span data-contrast=\"auto\">\u00a0&#8212; Clinical Infectious Diseases (June 6)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/arxiv.org\/abs\/2004.07052\"><span data-contrast=\"none\">Social network-based distancing strategies to flatten the COVID 19 curve in a post-lockdown world<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">\u00a0pre-print (May 27)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1016\/j.puhe.2020.05.017\"><span data-contrast=\"none\">US deportation policies in the time of COVID-19: a public health threat to the Americas<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Public<\/span><span data-contrast=\"auto\">\u00a0Health (May 22)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1056\/NEJMp2016259\"><span data-contrast=\"none\">Putting the Public Back in Public Health &#8211; Surveying Symptoms of Covid-19<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">\u00a0New England Journal of Medicine (June 5)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1038\/s41587-020-0577-1\"><span data-contrast=\"none\">Implications of antibody-dependent enhancement of infection for SARS-CoV-2 countermeasures<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">\u00a0Nature Biotechnology (June 5)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1038\/s41584-020-0448-7\"><span data-contrast=\"none\">Autoimmune and inflammatory diseases following COVID-19<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">\u00a0Nature Reviews<\/span><span data-contrast=\"auto\">\u00a0Rheumatology (June 4)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.15585\/mmwr.mm6923e2\"><span data-contrast=\"none\">Knowledge and Practices Regarding Safe Household Cleaning and Disinfection for COVID-19 Prevention \u2014 United States, May 2020<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">\u00a0MMWR (June 5)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1038\/s41577-020-0358-6\"><span data-contrast=\"none\">COVID-19 Vaccines: Neutralizing Antibodies and the Alum Advantage<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">\u00a0Nature Reviews<\/span><span data-contrast=\"auto\">\u00a0Immunology (June 4)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1038\/s41586-020-2281-1\"><span data-contrast=\"none\">The online competition between pro- and anti-vaccination views<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">\u00a0Nature (May 13)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1111\/jgs.16669\"><span data-contrast=\"none\">COVID\u201019 deaths in long term care facilities \u2010 a critical piece of the pandemic puzzle<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">\u00a0Journal of the American Geriatrics Society (June 5)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1001\/jamapediatrics.2020.2422\"><span data-contrast=\"none\">Simulated Assessment of Pharmacokinetically Guided Dosing for Investigational Treatments of Pediatric Patients With Coronavirus Disease 2019<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">\u00a0JAMA Pediatrics (June 5)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1001\/jama.2020.10370\"><span data-contrast=\"none\">SARS-CoV-2\u2013Related Inflammatory Multisystem Syndrome in Children<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">\u00a0JAMA (June 8)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1001\/jama.2020.8883\"><span data-contrast=\"none\">Caring for Women Who Are Planning a Pregnancy, Pregnant, or Postpartum During the COVID-19 Pandemic<\/span><\/a><span data-contrast=\"auto\">\u00a0&#8212; JAMA Insights (June 5)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.5858\/arpa.2020-0255-LE\"><span data-contrast=\"none\">Analysis of COVID-19 transmission: Low risk of presymptomatic spread?<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">\u00a0Archives of Pathology &amp; Laboratory Medicine<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1056\/NEJMp2017739\"><span data-contrast=\"none\">Waiting for Certainty on Covid-19 Antibody Tests &#8211; At What Cost?<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013<\/span><span data-contrast=\"auto\">\u00a0New England Journal of Medicine (June 5)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1056\/NEJMp2015897\"><span data-contrast=\"none\">False Negative Tests for SARS-CoV-2 Infection \u2014 Challenges and Implications<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 New England Journal of Medicine (June 5)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Stay-at-home orders were associated with decreases in reports of robberies and traffic stops and increases in domestic violence calls in Los Angeles and Indianapolis. <\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/08\/effects-of-non-pharmaceutical-interventions-on-covid-19-cases-deaths-and-demand-for-hospital-services-in-the-uk-a-modelling-study\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":7413,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[5],"tags":[],"topic":[],"class_list":["post-7388","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19-literature-situation-report"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7388","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7388"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7388\/revisions"}],"predecessor-version":[{"id":7414,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7388\/revisions\/7414"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media\/7413"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7388"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7388"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7388"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7388"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}