{"id":7425,"date":"2021-03-23T13:48:07","date_gmt":"2021-03-23T20:48:07","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7425"},"modified":"2021-03-25T13:48:58","modified_gmt":"2021-03-25T20:48:58","slug":"reduced-bnt162b2-mrna-vaccine-response-in-sars-cov-2-naive-nursing-home-residents","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/23\/reduced-bnt162b2-mrna-vaccine-response-in-sars-cov-2-naive-nursing-home-residents\/","title":{"rendered":"Reduced BNT162b2 MRNA Vaccine Response in SARS-CoV-2-Naive Nursing Home Residents"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">[Pre-print, not peer-reviewed]<\/span><\/i><span style=\"font-weight: 400\"> Nursing home (NH) residents had blunted antibody responses following vaccination with BNT162b2 mRNA vaccine (Moderna) when compared to healthcare workers. SARS-CoV-2-naive NH residents mounted antibody responses with nearly 4-fold lower median neutralization titers and half the anti-spike level compared to SARS-CoV-2-naive healthcare workers. In contrast, NH residents who had recovered from infection and were subsequently vaccinated had neutralization, anti-spike, and anti-RBD titers similar to healthcare workers who had recovered from infection and were subsequently vaccinated.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Canaday et al.\u00a0(Mar 22, 2021). Reduced BNT162b2 MRNA Vaccine Response in SARS-CoV-2-Naive Nursing Home Residents. Pre-print downloaded Mar 23 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.03.19.21253920\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2021.03.19.21253920<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] Nursing home (NH) residents had blunted antibody responses following vaccination with BNT162b2 mRNA vaccine (Moderna) when compared to healthcare workers. SARS-CoV-2-naive NH residents mounted antibody responses with nearly 4-fold lower median neutralization titers and half the anti-spike level compared to SARS-CoV-2-naive healthcare workers. In contrast, NH residents who had recovered from infection&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/23\/reduced-bnt162b2-mrna-vaccine-response-in-sars-cov-2-naive-nursing-home-residents\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32,33],"topic":[31],"class_list":["post-7425","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","tag-vaccines","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7425","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7425"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7425\/revisions"}],"predecessor-version":[{"id":7426,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7425\/revisions\/7426"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7425"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7425"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7425"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7425"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}