{"id":7431,"date":"2021-03-23T13:51:04","date_gmt":"2021-03-23T20:51:04","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7431"},"modified":"2021-03-25T13:51:58","modified_gmt":"2021-03-25T20:51:58","slug":"exposure-to-sars-cov-2-generates-t-cell-memory-in-the-absence-of-a-detectable-viral-infection","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/23\/exposure-to-sars-cov-2-generates-t-cell-memory-in-the-absence-of-a-detectable-viral-infection\/","title":{"rendered":"Exposure to SARS-CoV-2 Generates T-Cell Memory in the Absence of a Detectable Viral Infection"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Exposure to SARS-CoV-2 may still lead to the development of SARS-CoV-2-specific memory T cells in the absence of detectable SARS-CoV-2 virus or antibodies against SARS-CoV-2 antigens (spike and nucleocapsid). In blood samples collected from 69 individuals between 48 and 86 days after close contact with an individual with a confirmed SARS-CoV-2 infection, 58% and 14% of individuals developed SARS-CoV-2-specific CD4+ and CD8+ T cells, respectively. In contrast, only 3.7% of blood samples from 63 healthy donors collected before September 2019 contained detectable levels of CD4+ and CD8+ T cells.\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Wang et al.\u00a0(Dec 19, 2021). Exposure to SARS-CoV-2 Generates T-Cell Memory in the Absence of a Detectable Viral Infection. Nature Communications. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1038\/s41467-021-22036-z\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1038\/s41467-021-22036-z<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Exposure to SARS-CoV-2 may still lead to the development of SARS-CoV-2-specific memory T cells in the absence of detectable SARS-CoV-2 virus or antibodies against SARS-CoV-2 antigens (spike and nucleocapsid). In blood samples collected from 69 individuals between 48 and 86 days after close contact with an individual with a confirmed SARS-CoV-2 infection, 58% and 14%&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/23\/exposure-to-sars-cov-2-generates-t-cell-memory-in-the-absence-of-a-detectable-viral-infection\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32],"topic":[31],"class_list":["post-7431","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7431","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7431"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7431\/revisions"}],"predecessor-version":[{"id":7432,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7431\/revisions\/7432"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7431"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7431"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7431"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7431"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}