{"id":7534,"date":"2020-06-15T14:54:10","date_gmt":"2020-06-15T21:54:10","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7534"},"modified":"2021-03-25T14:54:50","modified_gmt":"2021-03-25T21:54:50","slug":"natural-history-of-asymptomatic-sars-cov-2-infection","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/15\/natural-history-of-asymptomatic-sars-cov-2-infection\/","title":{"rendered":"Natural History of Asymptomatic SARS-CoV-2 Infection"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Sakurai et al.<\/span><span data-contrast=\"auto\">\u00a0reported\u00a0<\/span><span data-contrast=\"auto\">a case series<\/span><span data-contrast=\"auto\">\u00a0of 90 patients from the\u202fDiamond Princess\u00a0<\/span><span data-contrast=\"auto\">cruise ship\u00a0<\/span><span data-contrast=\"auto\">who were asymptomatic when\u00a0<\/span><span data-contrast=\"auto\">they\u00a0<\/span><span data-contrast=\"auto\">tested positive for SARS-CoV-2, and\u00a0remained asymptomatic throughout the course of the infection. The median number of days between the first positive PCR result and the first of the two serial negative results was 9 days (IQR 6-11<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0range 3-21), and the cumulative percentages of people with resolution of infection within 8 and 15 days after the first positive result were 48% and 90%, respectively. The<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">likelihood<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">of delayed resolution increased with age.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Sakurai et al. (June 12, 2020). Natural History of Asymptomatic SARS-CoV-2 Infection. New England Journal of Medicine.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1056\/NEJMc2013020\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1056\/NEJMc2013020<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sakurai et al.\u00a0reported\u00a0a case series\u00a0of 90 patients from the\u202fDiamond Princess\u00a0cruise ship\u00a0who were asymptomatic when\u00a0they\u00a0tested positive for SARS-CoV-2, and\u00a0remained asymptomatic throughout the course of the infection. The median number of days between the first positive PCR result and the first of the two serial negative results was 9 days (IQR 6-11,\u00a0range 3-21), and the cumulative percentages&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/15\/natural-history-of-asymptomatic-sars-cov-2-infection\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[21],"class_list":["post-7534","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-transmission"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7534","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7534"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7534\/revisions"}],"predecessor-version":[{"id":7535,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7534\/revisions\/7535"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7534"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7534"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7534"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7534"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}