{"id":7538,"date":"2020-06-15T14:55:57","date_gmt":"2020-06-15T21:55:57","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7538"},"modified":"2021-03-25T14:56:39","modified_gmt":"2021-03-25T21:56:39","slug":"nasal-swab-testing-misses-patients-with-low-sars-cov-2-viral-loads","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/15\/nasal-swab-testing-misses-patients-with-low-sars-cov-2-viral-loads\/","title":{"rendered":"Nasal-Swab Testing Misses Patients with Low SARS-CoV-2 Viral Loads"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Callahan et al.<\/span><span data-contrast=\"auto\">\u00a0compared results of nasal specimens under 3 transport conditions, traditional viral transport media (VTM), GITC transport medium<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0and dry swabs, to those of standard nasopharynx swabs collected at the same time among 308\u00a0<\/span><span data-contrast=\"auto\">individuals<\/span><span data-contrast=\"auto\">. They observed high concordance (Cohen&#8217;s kappa &gt;0.8) only for patients with viral loads (VL)\u00a0<\/span><span data-contrast=\"auto\">from the nasal samples\u00a0<\/span><span data-contrast=\"auto\">&gt;1000 copies\/mL<\/span><span data-contrast=\"auto\">.\u00a0There was<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">low concordance (Cohen&#8217;s kappa = 0.49)\u00a0<\/span><span data-contrast=\"auto\">for<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">those with VL&lt;1000 copies\/mL<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Callahan et al. (June 14, 2020). Nasal-Swab Testing Misses Patients with Low SARS-CoV-2 Viral Loads. Pre-print\u00a0downloaded June 15 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.06.12.20128736\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.06.12.20128736<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[pre-print, not peer reviewed]\u00a0Callahan et al.\u00a0compared results of nasal specimens under 3 transport conditions, traditional viral transport media (VTM), GITC transport medium,\u00a0and dry swabs, to those of standard nasopharynx swabs collected at the same time among 308\u00a0individuals. They observed high concordance (Cohen&#8217;s kappa &gt;0.8) only for patients with viral loads (VL)\u00a0from the nasal samples\u00a0&gt;1000 copies\/mL.\u00a0There&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/15\/nasal-swab-testing-misses-patients-with-low-sars-cov-2-viral-loads\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-7538","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7538","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7538"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7538\/revisions"}],"predecessor-version":[{"id":7539,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7538\/revisions\/7539"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7538"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7538"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7538"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7538"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}