{"id":758,"date":"2020-09-08T11:16:02","date_gmt":"2020-09-08T18:16:02","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=758"},"modified":"2020-09-10T12:18:25","modified_gmt":"2020-09-10T19:18:25","slug":"covid-19-literature-situation-report-sept-8-2020","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/08\/covid-19-literature-situation-report-sept-8-2020\/","title":{"rendered":"COVID-19 Literature Situation Report Sept. 8, 2020"},"content":{"rendered":"<p>The scientific literature on COVID-19 is rapidly evolving and these articles were selected for review based on their relevance to Washington State decision making around COVID-19 response efforts. Included in these Lit Reps are some manuscripts that have been made available online as pre-prints but have not yet undergone peer review. Please be aware of this when reviewing articles included in the Lit Reps.<\/p>\n<p>Today\u2019s summary is based on a review of 816 articles (726 published, 90 in preprint).<\/p>\n<h2>Key Takeaways<\/h2>\n<ul>\n<li>Non-randomized phase 1\/2 studies in Russia of adenovirus recombinant vaccines, rAD5 and rAd26, were well tolerated with no serious adverse events with. All participants (n=38 per vaccine) produced antibodies to the vaccines, and humoral and cellular immune responses were strong. <a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(20)31866-3\">More<\/a><\/li>\n<li>Compared to past flu seasons, hospitalizations for acute respiratory illnesses among young children in rural Alaska dropped dramatically in April, coinciding with control measures in response to the COVID-19 pandemic. <a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa1328\">More<\/a><\/li>\n<li>Cost modeling suggests that extensive social distancing with masks on college campuses could prevent up to 87% of COVID-19 cases at a cost of $168 per infection prevented. Addition of asymptomatic testing every 3 days could prevent 96% of cases, but could markedly increase the cost, depending on the price of the tests. <a href=\"https:\/\/doi.org\/10.1101\/2020.09.03.20187062\">More<\/a><\/li>\n<li>Convalescent plasma transfusion was not associated with a reduction in mortality or progression to severe COVID-19 in a randomized clinical trial among participants with moderate COVID-19 in India. <a href=\"https:\/\/doi.org\/10.1101\/2020.09.03.20187252\">More<\/a><\/li>\n<\/ul>\n<div id=\"uw-accordion-shortcode\">\n<h3>Article Summaries<\/h3>\n<div class=\"js-accordion\" data-accordion-prefix-classes=\"uw-accordion-shortcode\">\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\">Non-Pharmaceutical Interventions<\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-761\" class=\"su-post\">\n<h5 class=\"su-post-title\">Prevalence and Predictors of Early COVID-19 Behavioral Intentions in the United States<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li>People who expressed higher levels of self-efficacy, perceived severity of COVID-19 illness, and a belief that prevention measures would be effective were more like to plan to engage in eight behaviors designated as critical by the CDC for the prevention of COVID-19. The authors suggest that public health messaging should focus on the severity of COVID-19 and the relative ease of engaging in the preventative methods.<\/li>\n<\/ul>\n<p><em>Berg and Lin. (Sept 7, 2020). Prevalence and Predictors of Early COVID-19 Behavioral Intentions in the United States. Translational Behavioral Medicine. <a href=\"https:\/\/doi.org\/10.1093\/tbm\/ibaa085\">https:\/\/doi.org\/10.1093\/tbm\/ibaa085<\/a><\/em><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\">Testing and Treatment<\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-763\" class=\"su-post\">\n<h5 class=\"su-post-title\">Convalescent Plasma in the Management of Moderate COVID-19 in India An Open-Label Parallel-Arm Phase II Multicentre Randomized Controlled Trial (PLACID Trial)<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li>[Pre-print, not peer-reviewed] COVID-19 convalescent plasma infusion was not associated with a reduction in mortality or progression to severe COVID-19 at 28 days post-enrollment (aOR=1.1, 95% CI: 0.7, 1.8) in a randomized trial among persons with moderate COVID-19 in India (n=464). Death or progression to severe disease occurred in 18.7% of participants in the intervention arm and 17.9% in the control arm.<\/li>\n<li>Participants in the intervention arm received two doses of 200 mL convalescent plasma that were transfused 24 hours apart. An analysis limited to participants who received infusions within three days of symptom onset also found no significant difference in the composite outcome between intervention and control groups (aOR=0.6, 95% CI 0.2, 1.2).<\/li>\n<\/ul>\n<p><em>Agarwal et al. (Sept 8, 2020). Convalescent Plasma in the Management of Moderate COVID-19 in India An Open-Label Parallel-Arm Phase II Multicentre Randomized Controlled Trial (PLACID Trial). Pre-print downloaded Sep 8 from <a href=\"https:\/\/doi.org\/10.1101\/2020.09.03.20187252\">https:\/\/doi.org\/10.1101\/2020.09.03.20187252<\/a><\/em><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\">Vaccines and Immunity<\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-765\" class=\"su-post\">\n<h5 class=\"su-post-title\">Safety and Immunogenicity of an RAd26 and RAd5 Vector-Based Heterologous Prime-Boost COVID-19 Vaccine in Two Formulations: Two Open, Non-Randomised Phase 1\/2 Studies from Russia<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li>Findings from two, non-randomized phase 1\/2 studies (n=38 per study) conducted in Russia of recombinant vaccines based on adenovirus type 5 (rAd5) and type 26 (rAd26) show that both vaccine formulations were well tolerated with no serious adverse events reported.<\/li>\n<li>All participants produced SARS-CoV-2 antibodies, and the vaccines induced strong humoral and cellular immune responses in participants.<\/li>\n<\/ul>\n<p>Logunov et al. (Sept 4, 2020). Safety and Immunogenicity of an RAd26 and RAd5 Vector-Based Heterologous Prime-Boost COVID-19 Vaccine in Two Formulations: Two Open, Non-Randomised Phase 1\/2 Studies from Russia. The Lancet. <a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(20)31866-3\">https:\/\/doi.org\/10.1016\/S0140-6736(20)31866-3<\/a><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\">Clinical Characteristics and Health Care Setting<\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-767\" class=\"su-post\">\n<h5 class=\"su-post-title\">Clinical Analysis of Neonates Born to Mothers with or without COVID-19: A Retrospective Analysis of 48 Cases from Two Neonatal Intensive Care Units in Hubei Province<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li>There were no vertical transmissions of SARS-CoV-2 from mother to neonate nor differences in clinical manifestations, radiological and biochemical results among neonates born to 15 women with confirmed and 17 with suspected COVID-19 who delivered in Hubei Province in China.<\/li>\n<\/ul>\n<p><em>Liu et al. (Sept 6, 2020). Clinical Analysis of Neonates Born to Mothers with or without COVID-19: A Retrospective Analysis of 48 Cases from Two Neonatal Intensive Care Units in Hubei Province. American Journal of Perinatology. <a href=\"https:\/\/doi.org\/10.1055\/s-0040-1716505\">https:\/\/doi.org\/10.1055\/s-0040-1716505<\/a><\/em><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\">Mental Health and Personal Impact<\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-773\" class=\"su-post\">\n<h5 class=\"su-post-title\">The Effect of COVID-19 Pandemic and Social Restrictions on Depression Rates and Maternal Attachment in Immediate Postpartum Women<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li>Based on a screening questionnaire for post-partum depression, 15% of women (n=223) whose last trimester of pregnancy overlapped with national lockdowns in Turkey and gave birth in a tertiary care center with strong hospital restrictions were considered at risk for postpartum depression, compared to an estimate of 8% of post-partum women in a period prior to the pandemic. These women also had lower Maternal Attachment Inventory scores than women who were not at risk for postpartum depression.<\/li>\n<\/ul>\n<p><em>Oskovi-Kaplan et al. (Sept 4, 2020). The Effect of COVID-19 Pandemic and Social Restrictions on Depression Rates and Maternal Attachment in Immediate Postpartum Women: A Preliminary Study. Psychiatric Quarterly. <a href=\"https:\/\/doi.org\/10.1007\/s11126-020-09843-1\">https:\/\/doi.org\/10.1007\/s11126-020-09843-1<\/a><\/em><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-771\" class=\"su-post\">\n<h5 class=\"su-post-title\">Population Anxiety and Positive Behaviour Change during the COVID\u201019 Epidemic: Cross\u2010sectional Surveys in Singapore, China and Italy<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li>Cross-sectional surveys in Singapore, China, and Italy (n=4,505) show that respondents reported high awareness of COVID-19 and its symptoms, and similarly high levels of information sufficiency, adherence, and acceptance to public health control measures. Higher self-efficacy was associated with lower anxiety levels, while superstition, fatalism, and considering messaging apps as the most trustworthy sources were associated with higher anxiety levels.<\/li>\n<\/ul>\n<p>Lim et al. (Sept 5, 2020). Population Anxiety and Positive Behaviour Change during the COVID\u201019 Epidemic: Cross\u2010sectional Surveys in Singapore, China and Italy. Influenza and Other Respiratory Viruses. <a href=\"https:\/\/doi.org\/10.1111\/irv.12785\">https:\/\/doi.org\/10.1111\/irv.12785<\/a><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-769\" class=\"su-post\">\n<h5 class=\"su-post-title\">Early Effects of the COVID-19 Pandemic on Physical Activity and Sedentary Behavior in Children Living in the U.S.<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li>US parents responding to an online survey reported that the most common physical activities during April to May 2020 for children (n=211, mean age=8.3 years) were free play\/unstructured activity (90%) and going for a walk (55%). Children engaged in about 90\u2009min of school-related sitting and over 8\u2009hours of leisure-related sitting per day.<\/li>\n<li>Parents of children ages 9-13 years were more likely to perceive a greater decrease of physical activity compared to parents of children ages 5-8.<\/li>\n<\/ul>\n<p><em>Dunton et al. (Dec 4, 2020). Early Effects of the COVID-19 Pandemic on Physical Activity and Sedentary Behavior in Children Living in the U.S. BMC Public Health. <a href=\"https:\/\/doi.org\/10.1186\/s12889-020-09429-3\">https:\/\/doi.org\/10.1186\/s12889-020-09429-3<\/a><\/em><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\">Modeling and Prediction <\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-779\" class=\"su-post\">\n<h5 class=\"su-post-title\">Frequency and Accuracy of Proactive Testing for COVID-19<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li>[Pre-print, not peer-reviewed]In the context of outbreak control on university campuses, Bergstrom et al. modeled the potential trade-offs of testing accuracy, frequency, and delay of results and found that even with a false negative rate of 30%, testing every second day can reduce R<sub>0<\/sub> from 2.5 to below 1 given a one day delay of results.<\/li>\n<li>Even if tests are done daily, a 2-day delay would not be able to lower R<sub>0<\/sub> below 1.<\/li>\n<\/ul>\n<p><em>Bergstrom et al. (Sept 8, 2020). Frequency and Accuracy of Proactive Testing for COVID-19. Pre-print downloaded Sep 8 from <a href=\"https:\/\/doi.org\/10.1101\/2020.09.05.20188839\">https:\/\/doi.org\/10.1101\/2020.09.05.20188839<\/a><\/em><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-777\" class=\"su-post\">\n<h5 class=\"su-post-title\">Local Lockdowns Outperform Global Lockdown on the Far Side of the COVID-19 Epidemic Curve<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li>Based on a modeling study based on Ontario, Canada, enacting lockdown policies at the county level would cause significantly fewer person-days of closure compared to enacting them at the province level, even under the same trigger threshold for cases and in a scenario with high intercounty travel. The authors conclude that these findings suggest local strategies may be better suited for handling the tail-end of the pandemic.<\/li>\n<\/ul>\n<p><em>Karatayev et al. (Sept 4, 2020). Local Lockdowns Outperform Global Lockdown on the Far Side of the COVID-19 Epidemic Curve. Proceedings of the National Academy of Sciences. <a href=\"https:\/\/doi.org\/10.1073\/pnas.2014385117\">https:\/\/doi.org\/10.1073\/pnas.2014385117<\/a><\/em><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-775\" class=\"su-post\">\n<h5 class=\"su-post-title\">College Campuses and COVID-19 Mitigation Clinical and Economic Value<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li>[Pre-print, not peer-reviewed] Cost modeling indicates that implementing extensive social distancing with masks on college campuses could prevent up to 87% of COVID-19 cases at a cost of $168 per case prevented. Adding lab testing of asymptomatic students every 3 days would prevent up to 96% of cases, but would raise the cost to $8,300 per case prevented for tests that cost $10 per test. Using a $1 test would cost $275 per case prevented.<\/li>\n<\/ul>\n<p><em>Losina et al. (Sept 5, 2020). College Campuses and COVID-19 Mitigation Clinical and Economic Value. Pre-print downloaded Sep 8 from <a href=\"https:\/\/doi.org\/10.1101\/2020.09.03.20187062\">https:\/\/doi.org\/10.1101\/2020.09.03.20187062<\/a><\/em><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\">Public Health Policy and Practice<\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-787\" class=\"su-post\">\n<h5 class=\"su-post-title\">Variations in State-Level SARS-COV-2 Testing Recommendations in the United States March-July 2020<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li>[Pre-print, not peer-reviewed] As of July 2020, only 16 states had recommended asymptomatic testing of the public, while 9 states actively recommended against it. The per capita rate of COVID-19 tests reported in each state correlated with more permissive testing recommendations and with higher epidemic intensity. Higher per capita testing was weakly associated with more complete reporting of COVID-19 deaths.<\/li>\n<\/ul>\n<p><em>Perniciaro et al. (Sept 7, 2020). Variations in State-Level SARS-COV-2 Testing Recommendations in the United States March-July 2020. Pre-print downloaded Sep 8 from <a href=\"https:\/\/doi.org\/10.1101\/2020.09.04.20188326\">https:\/\/doi.org\/10.1101\/2020.09.04.20188326<\/a><\/em><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-785\" class=\"su-post\">\n<h5 class=\"su-post-title\">Reaching Invisible and Unprotected Workers on Farms during the Coronavirus Pandemic<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li>The Cornell Farmworker Program, in partnership with Finger Lakes Community Health, implemented an approach to support farmworkers by creating a language concordant text messaging system that reached over 3,000 farmworkers and a webinar to communicate COVID-19 information regarding safety and regulations in which over 500 farmworkers participated.<\/li>\n<\/ul>\n<p><em>Dudley. (Sept 7, 2020). Reaching Invisible and Unprotected Workers on Farms during the Coronavirus Pandemic. Journal of Agromedicine. <a href=\"https:\/\/doi.org\/10.1080\/1059924X.2020.1815625\">https:\/\/doi.org\/10.1080\/1059924X.2020.1815625<\/a><\/em><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-783\" class=\"su-post\">\n<h5 class=\"su-post-title\">Racial and Ethnic Differences in Self-Reported Telehealth Use during the COVID-19 Pandemic: A Secondary Analysis of a U.S. Survey of Internet Users from Late March<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li>Compared to white respondents, Black respondents to a Pew survey (n=10,624) had a 1.4-fold higher odds of reporting that they had used telehealth as a result of the COVID-19 pandemic. The association was particularly strong among respondents who perceived the COVID-19 pandemic to be a minor threat (aOR=1.92).<\/li>\n<\/ul>\n<p>Campos-Castillo and Anthony. (Sept 7, 2020). Racial and Ethnic Differences in Self-Reported Telehealth Use during the COVID-19 Pandemic: A Secondary Analysis of a U.S. Survey of Internet Users from Late March. Journal of the American Medical Informatics Association. <a href=\"https:\/\/doi.org\/10.1093\/jamia\/ocaa221\">https:\/\/doi.org\/10.1093\/jamia\/ocaa221<\/a><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-781\" class=\"su-post\">\n<h5 class=\"su-post-title\">Impact of Social Distancing and Travel Restrictions on Non-COVID-19 Respiratory Hospital Admissions in Young Children in Rural Alaska<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li>Hospitalizations of young children due to acute respiratory illnesses (ARI) dropped dramatically in April 2020 in rural Alaska, in contrast to the past 10 seasons, when the seasonal decline began in June. Among 26 seasons of data, no season prior to the COVID-19 pandemic season also had a four-week stretch with no ARI admissions, demonstrating the potential secondary benefits of physical distancing and travel restrictions.<\/li>\n<\/ul>\n<p><em>Nolen et al. (Sept 5, 2020). Impact of Social Distancing and Travel Restrictions on Non-COVID-19 Respiratory Hospital Admissions in Young Children in Rural Alaska. Clinical Infectious Diseases. <a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa1328\">https:\/\/doi.org\/10.1093\/cid\/ciaa1328<\/a><\/em><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<h2>Other Resources and Commentaries<\/h2>\n<ul>\n<li><a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(20)31858-4\">COVID-19 Exacerbates Violence against Health Workers<\/a> \u2013 The Lancet (Sept 5)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.1038\/s41577-020-00434-6\">Immunological Considerations for COVID-19 Vaccine Strategies<\/a> \u2013 Nature Reviews Immunology<br \/>\n(Sept 4)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(20)31856-0\">COVID-19: A New Lens for Non-Communicable Diseases<\/a> \u2013 The Lancet (Sept 5)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.1038\/d41586-020-02557-1\">US University Workers Fight a Return to Campus as COVID-19 Cases Grow<\/a> \u2013 Nature (Sept 4)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.7326\/M20-3569\">Attitudes Toward a Potential SARS-CoV-2 Vaccine: A Survey of U.S. Adults<\/a> \u2013 Annals of Internal Medicine (Sept 4)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.1002\/jmv.26487\">Presenting Characteristics, Smoking versus Diabetes and Outcome among Patients Hospitalized with COVID\u201019<\/a> \u2013 Journal of Medical Virology (Sept 4)<\/li>\n<li><a href=\"http:\/\/www.psychiatria-danubina.com\/UserDocsImages\/pdf\/dnb_vol32_noSuppl%201\/dnb_vol32_noSuppl%201_15.pdf\">Humor in the Age of COVID-19 Lockdown: An Explorative Qualitative Study<\/a> \u2013 Psychiatria Danubina (Sept 5)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.1136\/bjsports-2020-102856\">Social Distancing and COVID-19: An Unprecedented Active Transport Public Health Opportunity<\/a> \u2013 British Journal of Sports Medicine (Sept 7)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.1111\/tbed.13819\">Decreased Case Fatality Rate of COVID\u201019 in the Second Wave: A Study in 53 Countries or Regions<\/a> \u2013 Transboundary and Emerging Diseases (Sept 6)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.1111\/jgs.16810\">Factors Associated with Nursing Homes\u2019 Late Participation in COVID-19 Reporting<\/a> \u2013 Journal of the American Geriatrics Society (Sept 7)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.ijid.2020.08.076\">Asymptomatic SARS Coronavirus 2 Infection: Invisible yet Invincible<\/a> \u2013 International Journal of Infectious Diseases (Sept 3)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.1017\/dmp.2020.228\">Interdisciplinary Information for Infectious Disease Response: Exercising for Improved Medical\/Public Health Communication and Collaboration<\/a> \u2013 Disaster Medicine and Public Health Preparedness (Sept 8)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa1338\">SARS-CoV-2 RNA in Plasma Is Associated with ICU Admission and Mortality in Patients Hospitalized with COVID-19<\/a> \u2013 Clinical Infectious Diseases (Sept 5)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.1093\/pubmed\/fdaa159\">Years of Life Lost Associated with COVID-19 Deaths in the United States<\/a> \u2013 Journal of Public Health (Sept 7)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.prrv.2020.08.001\">Multi-System Inflammatory Syndrome in Children &amp;amp; Adolescents (MIS-C): A Systematic Review of Clinical Features and Presentation<\/a> \u2013 Paediatric Respiratory Reviews (Aug 11)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa1327\">COVID-19 and HIV Spotlight the U.S. Imperative for Permanent Affordable Housing<\/a> \u2013 Clinical Infectious Diseases (Sept 5)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.1101\/2020.09.05.20188912\">Beneficial and Harmful Outcomes of Tocilizumab in Severe COVID-19 A Systematic Review and Meta-Analysis<\/a> \u2013 medRxiv (Sept 8)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.34172\/ijhpm.2020.167\">What Is COVID-19 Teaching Us About Community Health Systems? A Reflection From a Rapid Community-Led Mutual Aid Response in Cape Town, South Africa<\/a> \u2013 International Journal of Health Policy and Management (Sept 1)<\/li>\n<li><a href=\"https:\/\/doi.org\/10.1002\/jmv.26491\">Clinical Characteristics, Cause Analysis and Infectivity of COVID\u201019 Nucleic Acid Re\u2010positive Patients: A Literature Review<\/a> \u2013 Journal of Medical Virology. (Sept 5)<\/li>\n<\/ul>\n<p>Report prepared by the UW MetaCenter for Pandemic Preparedness and Global Health Security and the START Center in collaboration with and on behalf of WA DOH COVID-19 Incident Management Team.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Key Takeaways: Non-randomized phase 1\/2 studies in Russia of adenovirus recombinant vaccines, rAD5 and rAd26, were well tolerated with no serious adverse events with. All participants (n=38 per vaccine) produced antibodies to the vaccines, and humoral and cellular immune responses were strong<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/08\/impact-of-social-distancing-and-travel-restrictions-on-non-covid-19-respiratory-hospital-admissions-in-young-children-in-rural-alaska\/\">Read more<\/a><\/div>\n","protected":false},"author":3,"featured_media":343,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[5],"tags":[],"topic":[],"class_list":["post-758","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19-literature-situation-report"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/758","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=758"}],"version-history":[{"count":3,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/758\/revisions"}],"predecessor-version":[{"id":790,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/758\/revisions\/790"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media\/343"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=758"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=758"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=758"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=758"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}