{"id":765,"date":"2020-09-08T12:05:05","date_gmt":"2020-09-08T19:05:05","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=765"},"modified":"2020-09-10T12:06:16","modified_gmt":"2020-09-10T19:06:16","slug":"safety-and-immunogenicity-of-an-rad26-and-rad5-vector-based-heterologous-prime-boost-covid-19-vaccine-in-two-formulations-two-open-non-randomised-phase-1-2-studies-from-russia","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/08\/safety-and-immunogenicity-of-an-rad26-and-rad5-vector-based-heterologous-prime-boost-covid-19-vaccine-in-two-formulations-two-open-non-randomised-phase-1-2-studies-from-russia\/","title":{"rendered":"Safety and Immunogenicity of an RAd26 and RAd5 Vector-Based Heterologous Prime-Boost COVID-19 Vaccine in Two Formulations: Two Open, Non-Randomised Phase 1\/2 Studies from Russia"},"content":{"rendered":"<ul>\n<li>Findings from two, non-randomized phase 1\/2 studies (n=38 per study) conducted in Russia of recombinant vaccines based on adenovirus type 5 (rAd5) and type 26 (rAd26) show that both vaccine formulations were well tolerated with no serious adverse events reported.<\/li>\n<li>All participants produced SARS-CoV-2 antibodies, and the vaccines induced strong humoral and cellular immune responses in participants.<\/li>\n<\/ul>\n<p>Logunov et al. (Sept 4, 2020). Safety and Immunogenicity of an RAd26 and RAd5 Vector-Based Heterologous Prime-Boost COVID-19 Vaccine in Two Formulations: Two Open, Non-Randomised Phase 1\/2 Studies from Russia. The Lancet. <a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(20)31866-3\">https:\/\/doi.org\/10.1016\/S0140-6736(20)31866-3<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Findings from two, non-randomized phase 1\/2 studies (n=38 per study) conducted in Russia of recombinant vaccines based on adenovirus type 5 (rAd5) and type 26 (rAd26) show that both vaccine formulations were well tolerated with no serious adverse events reported. All participants produced SARS-CoV-2 antibodies, and the vaccines induced strong humoral and cellular immune responses&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/08\/safety-and-immunogenicity-of-an-rad26-and-rad5-vector-based-heterologous-prime-boost-covid-19-vaccine-in-two-formulations-two-open-non-randomised-phase-1-2-studies-from-russia\/\">Read more<\/a><\/div>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[31],"class_list":["post-765","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/765","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=765"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/765\/revisions"}],"predecessor-version":[{"id":766,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/765\/revisions\/766"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=765"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=765"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=765"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=765"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}