{"id":7678,"date":"2020-06-19T11:35:24","date_gmt":"2020-06-19T18:35:24","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7678"},"modified":"2021-03-26T11:48:12","modified_gmt":"2021-03-26T18:48:12","slug":"covid-19-literature-situation-report-june-19-2020","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/19\/covid-19-literature-situation-report-june-19-2020\/","title":{"rendered":"COVID-19 Literature Situation Report June 19, 2020"},"content":{"rendered":"<p>The scientific literature on COVID-19 is rapidly evolving and these articles were selected for review based on their relevance to Washington State decision making around COVID-19 response efforts. Included in these Lit Reps are some manuscripts that have been made available online as pre-prints but have not yet undergone peer review. Please be aware of this when reviewing articles included in the Lit Reps.<\/p>\n<h2>Key Takeaways<\/h2>\n<ul>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">A composite test for both SARS-CoV-2 virus and antibodies shows promise for rapid diagnosis with high\u00a0<\/span><\/b><b><span data-contrast=\"auto\">test validity<\/span><\/b><b><span data-contrast=\"auto\">.<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1101\/2020.06.16.20133157\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">Probable\u00a0<\/span><\/b><b><span data-contrast=\"auto\">anxiety disorders were found to have nearly doubled from pre-pandemic levels in two UK cohorts.<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1101\/2020.06.16.20133116\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">A study in the Baltimore\/Washington, D.C. region found that Latino patients were more likely than non-Latino patients to test positive for COVID-19, but\u00a0were less likely to be hospitalized.<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1001\/jama.2020.11374\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<div id=\"uw-accordion-shortcode\">\n<h3>Article Summaries<\/h3>\n<div class=\"js-accordion\" data-accordion-prefix-classes=\"uw-accordion-shortcode\">\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Non-Pharmaceutical Interventions<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7680\" class=\"su-post\">\n<h5 class=\"su-post-title\">Does Culture Matter Social Distancing under the COVID-19 Pandemic?<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"43\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-contrast=\"auto\">Using Google COVID-19 community mobility reports, Huynh demonstrated that countries with a higher \u201cUncertainty Avoidance Index\u201d had a lower proportion of people gathering in public, even after controlling for gross domestic product (GDP) per capita.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Huynh. (Oct\u00a02020).\u00a0Does Culture Matter Social Distancing under the COVID-19 Pandemic? Safety Science.<\/span><\/i><i><span data-contrast=\"auto\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.ssci.2020.104872\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.ssci.2020.104872<\/span><\/i><\/a><i><span data-contrast=\"auto\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Testing and Treatment<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7686\" class=\"su-post\">\n<h5 class=\"su-post-title\">Potent Neutralizing Monoclonal Antibodies Directed to Multiple Epitopes on the SARS-CoV-2 Spike<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"43\" data-aria-posinset=\"1\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0Among 16 SARS-CoV-2 neutralizing monoclonal antibodies from 5 patients with severe disease, 19 potently neutralized the virus\u00a0<\/span><i><span data-contrast=\"auto\">in vitro<\/span><\/i><span data-contrast=\"auto\">, 9 with exquisite potency. Several are promising candidates for treatment or prevention of COVID-19. These 19 antibodies were nearly equally divided between two regions at the top of the viral spike<\/span><span data-contrast=\"auto\">\u00a0\u2014<\/span><span data-contrast=\"auto\">\u00a0the receptor binding domain and the N-terminal domain<\/span><span data-contrast=\"auto\">\u00a0\u2014<\/span><span data-contrast=\"auto\">\u00a0demonstrating the immunogenicity of these regions.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Ho et al. (June 18, 2020). Potent Neutralizing Monoclonal Antibodies Directed to Multiple Epitopes on the SARS-CoV-2 Spike.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print downloaded June 19 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.06.17.153486\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.06.17.153486<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7684\" class=\"su-post\">\n<h5 class=\"su-post-title\">Combined Point of Care Nucleic Acid and Antibody Testing for SARS-CoV-2 a Prospective Cohort Study in Suspected Moderate to Severe COVID-19 Disease<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"43\" data-aria-posinset=\"1\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0Micochova\u00a0et al. compared a combined rapid test (nucleic acid amplification on nose\/throat swab and lateral flow assay antibody test on serum) suitable for point-of-care use with a composite gold standard on 45 patients with suspected moderate to severe COVID-19 disease. In days 1-7 of illness, sensitivity of the nucleic acid test alone was 79.2%, which increased to 100% when combined with the rapid antibody test. Specificity of the combined test in\u00a0<\/span><span data-contrast=\"auto\">days 1-7 of illness was 90% (95% CI 55.5-99.7%). These results show a potentially promising point-of-care approach that improves sensitivity while maintaining relatively high specificity.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Micochova\u00a0et al. (June 18, 2020). Combined Point of Care Nucleic Acid and Antibody Testing for SARS-CoV-2 a Prospective Cohort Study in Suspected Moderate to Severe COVID-19 Disease.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print downloaded June 19 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.06.16.20133157\"><i><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.06.16.20133157<\/span><\/i><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7682\" class=\"su-post\">\n<h5 class=\"su-post-title\">Association of\u00a0Angiotensin-Converting Enzyme Inhibitor or\u00a0Angiotensin Receptor Blocker Use With COVID-19 Diagnosis and Mortality<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"43\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">A retrospective cohort study<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">of<\/span><span data-contrast=\"auto\">\u00a04<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">480 patients with COVID-19<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">using data from\u00a0<\/span><span data-contrast=\"auto\">the\u00a0<\/span><span data-contrast=\"auto\">Danish national administrative registries<\/span><span data-contrast=\"auto\">\u00a0found that prior use of ACE inhibitors and angiotensin receptor blockers (ACEI\/ARBs) was not associated with higher mortality from COVID-19.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"43\" data-aria-posinset=\"2\" data-aria-level=\"1\"><i><span data-contrast=\"auto\">[EDITORIAL NOTE:\u00a0<\/span><\/i><i><span data-contrast=\"auto\">The article was accompanied by a\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jama.2020.11401\"><i><span data-contrast=\"none\">JAMA editorial<\/span><\/i><\/a><i><span data-contrast=\"auto\">\u00a0that concluded that when there is a clinical indication for their use, ACEI\/ARBs should not be discontinued in pati<\/span><\/i><i><span data-contrast=\"auto\">ents with COVID-19, unless the drugs cannot be tolerated due to hemodynamic instability.\u00a0<\/span><\/i><i><span data-contrast=\"auto\">However<\/span><\/i><i><span data-contrast=\"auto\">,<\/span><\/i><i><span data-contrast=\"auto\">\u00a0we note that adjusted models showed a significant or nearly\u00a0<\/span><\/i><i><span data-contrast=\"auto\">significant<\/span><\/i><i><span data-contrast=\"auto\">\u00a0modest association with severe COVID-19]<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Fosb\u00f8l et al. (June 19, 2020). Association of\u00a0<\/span><\/i><i><span data-contrast=\"none\">Angiotensin-Converting Enzyme Inhibitor or\u00a0<\/span><\/i><i><span data-contrast=\"none\">Angiotensin Receptor Blocker Use With COVID-19 Diagnosis and Mortality. JAMA.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jama.2020.11301\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jama.2020.11301<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Clinical Characteristics and Health Care Setting<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7690\" class=\"su-post\">\n<h5 class=\"su-post-title\">Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"43\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">A retrospective telephone survey of patients diagnosed with COVID-19 during March 5-23, 2020 (n=204) found that 57% reported reduction of taste and\/or smell prior to diagnosis and that 40% reported reduction of both taste and smell prior to diagnosis. 55% reported taste reduction and 41% reported smell reduction.\u00a0 Nasal obstruction was rare among patients with severe taste or smell reduction. Changes to taste and smell may be a frequent and early symptom of COVID-19.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Mercante et al. (June 18, 2020). Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019. JAMA Otolaryngology\u2013Head &amp; Neck Surgery.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jamaoto.2020.1155\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jamaoto.2020.1155<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7688\" class=\"su-post\">\n<h5 class=\"su-post-title\">The Cardiac Toxicity of Chloroquine or Hydroxychloroquine in COVID-19 Patients:\u00a0A Systematic Review and Meta-Regression Analysis<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"43\" data-aria-posinset=\"2\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0A systematic review and meta-analysis (n=19 studies; 5,652 patients) studied the incidence of cardiac endpoints among COVID-19 patients treated with chloroquine or hydroxychloroquine, including QT prolongation\u2014a potential precursor to the arrhythmias\u00a0torsades\u00a0de pointes (TdP) or ventricular tachycardia (VT) or cardiac arrest\u2014as well as\u00a0TdP\/VT or cardiac arrest. The pooled incidence was 90 per 1,000 for prolonged QTc, 3 per 1,000 for\u00a0TdP\/VT or cardiac arrest, and 50 per 1,000 for discontinuation of either medication due to prolonged QTc or arrhythmias. Treatment of COVID-19 patients with chloroquine or hydroxychloroquine is associated with a substantial risk of QTc prolongation and its sequelae.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Tleyjeh\u00a0et al. (June 18, 2020). The Cardiac Toxicity of Chloroquine or Hydroxychloroquine in COVID-19 Patients<\/span><\/i><i><span data-contrast=\"none\">:<\/span><\/i><i><span data-contrast=\"none\">\u00a0A Systematic Review and Meta-Regression Analysis.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print downloaded June 19 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.06.16.20132878\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.06.16.20132878<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun SCXW88278310 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW88278310 BCX0\" data-ccp-parastyle=\"heading 2\">Mental Health and Personal Impact<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7692\" class=\"su-post\">\n<h5 class=\"su-post-title\">Mental Health during the COVID-19 Pandemic in Two Longitudinal UK Population Cohorts<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"43\" data-aria-posinset=\"1\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0Two longitudinal cohorts in the UK collected validated mental health measures before and during the COVID-19 pandemic. Anxiety and lower wellbeing, but not depression,\u00a0increased\u00a0since the start of the pandemic. The percentage of individuals with probable anxiety disorder nearly doubled from 13% to 24%. Younger people, women, those with pre-existing\u00a0mental or physical health conditions, and those living alone and in socio-economic adversity were at a higher risk of these outcomes. There was no evidence that key workers or healthcare workers were at higher risk of these outcomes.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Kwong et al. (June 18, 2020). Mental Health during the COVID-19 Pandemic in Two Longitudinal UK Population Cohorts.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print downloaded June 19 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.06.16.20133116\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.06.16.20133116<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun SCXW222112860 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW222112860 BCX0\" data-ccp-parastyle=\"heading 2\">Public Health Policy and Practice<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7698\" class=\"su-post\">\n<h5 class=\"su-post-title\">SARS-CoV-2 Positivity Rate for Latinos in the Baltimore-Washington, DC Region<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"43\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Out of 37,727 patients from 5 hospitals who were tested for SARS-CoV-2 in the Baltimore\/Washington, D.C. region, 16.3% (95% CI 16.0-16.7%) tested positive. Prevalence was significantly higher for Latino patients (42.6%, 95% CI 41.1-44.1%), black patients (17.6%, 95% CI 16.6-18.3%) and patients of other non-white race\/ethnicity (17.2%, 95% CI 16.2-18.3%) compared to white patients (8.8%, 95% CI 8.4-9.2%). Trends in positivity peaked later for Latino patients than white or black patients. The hospital admission rate was lower for Latino patients (29.1%, 95% Ci 27.0-31.2%) than white patients (40.1%, 95% CI 37.6-42.5%) or black patients (41.7%, 95% CI 39.5-43.8%). Hospitalized Latino patients were younger and had lower rates of comorbidities than white or black patients.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Martinez et al. (June 18, 2020). SARS-CoV-2 Positivity Rate for Latinos in the Baltimore-Washington, DC Region. JAMA.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jama.2020.11374\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jama.2020.11374<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7696\" class=\"su-post\">\n<h5 class=\"su-post-title\">Disparities in Coronavirus 2019 Reported Incidence, Knowledge, and Behavior Among US Adults<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"43\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">A national survey conducted in March and April among US adults (n=5,198) found that\u00a0<\/span><span data-contrast=\"auto\">African American respondents, men, and younger people<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">had less accurate knowledge\u00a0<\/span><span data-contrast=\"auto\">about COVID-19 symptoms and preventive behaviors\u00a0<\/span><span data-contrast=\"auto\">than white respondents, women, and older individuals.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"43\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-contrast=\"auto\">Additionally, African American respondents were 3.5 percentage points more likely than white respondents to report having been infected with COVID-19, and men across race\/ethnicity groups were 3.2 percentage points more likely than women to report having been infected.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Alsan et al. (June 18, 2020). Disparities in Coronavirus 2019 Reported Incidence, Knowledge, and Behavior Among US Adults. JAMA Network Open.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.12403\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.12403<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7694\" class=\"su-post\">\n<h5 class=\"su-post-title\">Severe Acute Respiratory Syndrome Coronavirus 2 among Asymptomatic Workers Screened for Work Resumption, China<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"43\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Among 29,299 workers in Wuhan, China who were screened for SARS-CoV-2 by PCR prior to returning to work, 18 (0.061%) were positive, all of whom were asymptomatic. Of the 18 positives, 13 became negative within 8 days, and 41 of their close contacts tested negative. Among 22,633 workers tested for SARS-CoV-2 antibodies, 617 (3%) had positive IgG but negative IgM, 40 (0.2%) had negative IgG but positive IgM, and 196 (0.9%) were positive for both.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Han et al. (Sept 2020). Severe Acute Respiratory Syndrome Coronavirus 2 among Asymptomatic Workers Screened for Work Resumption, China. Emerging Infectious Diseases.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.3201\/eid2609.201848\"><span data-contrast=\"none\">https:\/\/doi.org\/10.3201\/eid2609.201848<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<h3><strong>Other Resources and Commentaries<\/strong><\/h3>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1101\/2020.06.18.158329\"><span data-contrast=\"none\">Polymorphism and selection pressure of SARS-CoV-2 vaccine and diagnostic antigens: implications for immune evasion and serologic diagnostic performance<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0<\/span><span data-contrast=\"auto\">bio<\/span><span data-contrast=\"auto\">R<\/span><span data-contrast=\"auto\">xiv<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">(June 18)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1101\/2020.06.16.20126425\"><span data-contrast=\"none\">COVID-19 projections for reopening Connecticut<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0medRxiv\u00a0(June 19)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.7759\/cureus.8136\"><span data-contrast=\"none\">Pathological Findings and Management of COVID-19 Patients: A Brief Overview of Modern-day Pandemic<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0Cureus\u00a0(May 15)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.3201\/eid2609.201495\"><span data-contrast=\"none\">Isolation, Sequence, Infectivity, and Replication Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Emerging Infectious Diseases<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/S2666-5247(20)30069-0\"><span data-contrast=\"none\">Host range of SARS-CoV-2 and implications for public health<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Lancet Microbe (June 18)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1001\/jama.2020.11254\"><span data-contrast=\"none\">COVID-19\u2019s Crushing Effects on Medical Practices, Some of Which Might Not Survive<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 JAMA (June 18)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1056\/NEJMcibr2009737\"><span data-contrast=\"none\">Amplifying RNA Vaccine Development<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 New England Journal of Medicine (June 18)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"http:\/\/doi.org\/10.1056\/NEJMsr2019953\"><span data-contrast=\"none\">Challenges of \u201cReturn to Work\u201d in an Ongoing Pandemic<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 New England Journal of Medicine (June 18)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1001\/jama.2020.11366\"><span data-contrast=\"none\">Economic Vulnerability of Households With Essential Workers<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 JAMA (June 18)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/S2215-0366(20)30241-8\"><span data-contrast=\"none\">Effects of the COVID-19 pandemic on the mental health of prisoners<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0The Lancet\u00a0Psychiatry\u00a0<\/span><br \/>\n<span data-contrast=\"auto\">(June 19)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(20)31352-0\"><span data-contrast=\"none\">Seeing COVID-19 through Jos\u00e9 Saramago&#8217;s Blindness<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 The Lancet (June 19)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>A composite test for both SARS-CoV-2 virus and antibodies shows promise for rapid diagnosis with high test validity. <\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/19\/severe-acute-respiratory-syndrome-coronavirus-2-among-asymptomatic-workers-screened-for-work-resumption-china\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":5840,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[5],"tags":[],"topic":[],"class_list":["post-7678","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19-literature-situation-report"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7678","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7678"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7678\/revisions"}],"predecessor-version":[{"id":7700,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7678\/revisions\/7700"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media\/5840"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7678"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7678"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7678"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7678"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}