{"id":7682,"date":"2020-06-19T11:38:19","date_gmt":"2020-06-19T18:38:19","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7682"},"modified":"2021-03-26T11:39:00","modified_gmt":"2021-03-26T18:39:00","slug":"association-of-angiotensin-converting-enzyme-inhibitor-or-angiotensin-receptor-blocker-use-with-covid-19-diagnosis-and-mortality","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/19\/association-of-angiotensin-converting-enzyme-inhibitor-or-angiotensin-receptor-blocker-use-with-covid-19-diagnosis-and-mortality\/","title":{"rendered":"Association of\u00a0Angiotensin-Converting Enzyme Inhibitor or\u00a0Angiotensin Receptor Blocker Use With COVID-19 Diagnosis and Mortality"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"43\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">A retrospective cohort study<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">of<\/span><span data-contrast=\"auto\">\u00a04<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">480 patients with COVID-19<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">using data from\u00a0<\/span><span data-contrast=\"auto\">the\u00a0<\/span><span data-contrast=\"auto\">Danish national administrative registries<\/span><span data-contrast=\"auto\">\u00a0found that prior use of ACE inhibitors and angiotensin receptor blockers (ACEI\/ARBs) was not associated with higher mortality from COVID-19.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"43\" data-aria-posinset=\"2\" data-aria-level=\"1\"><i><span data-contrast=\"auto\">[EDITORIAL NOTE:\u00a0<\/span><\/i><i><span data-contrast=\"auto\">The article was accompanied by a\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jama.2020.11401\"><i><span data-contrast=\"none\">JAMA editorial<\/span><\/i><\/a><i><span data-contrast=\"auto\">\u00a0that concluded that when there is a clinical indication for their use, ACEI\/ARBs should not be discontinued in pati<\/span><\/i><i><span data-contrast=\"auto\">ents with COVID-19, unless the drugs cannot be tolerated due to hemodynamic instability.\u00a0<\/span><\/i><i><span data-contrast=\"auto\">However<\/span><\/i><i><span data-contrast=\"auto\">,<\/span><\/i><i><span data-contrast=\"auto\">\u00a0we note that adjusted models showed a significant or nearly\u00a0<\/span><\/i><i><span data-contrast=\"auto\">significant<\/span><\/i><i><span data-contrast=\"auto\">\u00a0modest association with severe COVID-19]<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Fosb\u00f8l et al. (June 19, 2020). Association of\u00a0<\/span><\/i><i><span data-contrast=\"none\">Angiotensin-Converting Enzyme Inhibitor or\u00a0<\/span><\/i><i><span data-contrast=\"none\">Angiotensin Receptor Blocker Use With COVID-19 Diagnosis and Mortality. JAMA.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jama.2020.11301\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jama.2020.11301<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A retrospective cohort study\u00a0of\u00a04,480 patients with COVID-19\u00a0using data from\u00a0the\u00a0Danish national administrative registries\u00a0found that prior use of ACE inhibitors and angiotensin receptor blockers (ACEI\/ARBs) was not associated with higher mortality from COVID-19.\u00a0\u00a0 [EDITORIAL NOTE:\u00a0The article was accompanied by a\u00a0JAMA editorial\u00a0that concluded that when there is a clinical indication for their use, ACEI\/ARBs should not be discontinued&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/19\/association-of-angiotensin-converting-enzyme-inhibitor-or-angiotensin-receptor-blocker-use-with-covid-19-diagnosis-and-mortality\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-7682","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7682","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7682"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7682\/revisions"}],"predecessor-version":[{"id":7683,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7682\/revisions\/7683"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7682"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7682"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7682"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7682"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}