{"id":7766,"date":"2020-06-24T12:37:53","date_gmt":"2020-06-24T19:37:53","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7766"},"modified":"2021-03-26T12:55:28","modified_gmt":"2021-03-26T19:55:28","slug":"covid-19-literature-situation-report-june-24-2020","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/24\/covid-19-literature-situation-report-june-24-2020\/","title":{"rendered":"COVID-19 Literature Situation Report June 24, 2020"},"content":{"rendered":"<p>The scientific literature on COVID-19 is rapidly evolving and these articles were selected for review based on their relevance to Washington State decision making around COVID-19 response efforts. Included in these Lit Reps are some manuscripts that have been made available online as pre-prints but have not yet undergone peer review. Please be aware of this when reviewing articles included in the Lit Reps.<\/p>\n<h2>Key Takeaways<\/h2>\n<ul>\n<li><b><span data-contrast=\"auto\">A\u00a0<\/span><\/b><b><span data-contrast=\"auto\">college spring break trip\u00a0<\/span><\/b><b><span data-contrast=\"auto\">resulted in\u00a0<\/span><\/b><b><span data-contrast=\"auto\">SARS-CoV-2 infection in\u00a0<\/span><\/b><b><span data-contrast=\"auto\">60 (<\/span><\/b><b><span data-contrast=\"auto\">28<\/span><\/b><b><span data-contrast=\"auto\">%<\/span><\/b><b><span data-contrast=\"auto\">)<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">college-aged travelers and their contacts<\/span><\/b><b><span data-contrast=\"auto\">\u00a0included in the outbreak investigation<\/span><\/b><b><span data-contrast=\"auto\">, one-fifth of whom were asymptomatic at\u00a0<\/span><\/b><b><span data-contrast=\"auto\">the time of testing.<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><a href=\"https:\/\/doi.org\/10.15585\/mmwr.mm6926e1\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">Mathematical modeling suggests that lockdowns should remain in place for a minimum of 60 days, followed by a gradual reintroduction of the workforce.\u00a0<\/span><\/b><b><span data-contrast=\"auto\">The model indicates that p<\/span><\/b><b><span data-contrast=\"auto\">hysical<\/span><\/b><b><span data-contrast=\"auto\">\u00a0distancing,\u00a0<\/span><\/b><b><span data-contrast=\"auto\">face masks<\/span><\/b><b><span data-contrast=\"auto\">, and other individual protection measures had a massive impact\u00a0<\/span><\/b><b><span data-contrast=\"auto\">on\u00a0<\/span><\/b><b><span data-contrast=\"auto\">reducing the current peak of active cases. Notably, waning adheren<\/span><\/b><b><span data-contrast=\"auto\">c<\/span><\/b><b><span data-contrast=\"auto\">e to these interventions over time could result in a larger second epidemic wave.\u00a0<\/span><\/b><a href=\"https:\/\/doi.org\/10.1038\/s41562-020-0908-8\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">A\u00a0<\/span><\/b><b><span data-contrast=\"auto\">large<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">proportion of nursing home residents (24%) and staff (15%) tested positive for SAR-CoV-2 in Spain, the majority of whom were asymptomatic at the time of testing (70% and 56% of residents and staff, respectively).<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.3201\/eid2609.202603\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"3\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">Recovered COVID-19 patients commonly experience persistent SARS-CoV-2 positivity and fluctuating RT-PCR test results: 47% of hospitalized patients still tested<\/span><\/b><b><span data-contrast=\"auto\">\u00a0positive at symptom resolution,<\/span><\/b><b><span data-contrast=\"auto\">\u00a014% tested positive 14-days follow<\/span><\/b><b><span data-contrast=\"auto\">ing hospital discharge<\/span><\/b><b><span data-contrast=\"auto\">\u00a0and 91% of\u00a0<\/span><\/b><b><span data-contrast=\"auto\">patients who tested negative had<\/span><\/b><b><span data-contrast=\"auto\">\u00a0a subsequent positive test result when retested within the first month of being discharged.<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1016\/j.jinf.2020.06.024\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<div id=\"uw-accordion-shortcode\">\n<h3>Article Summaries<\/h3>\n<div class=\"js-accordion\" data-accordion-prefix-classes=\"uw-accordion-shortcode\">\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Transmission<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7776\" class=\"su-post\">\n<h5 class=\"su-post-title\">ACE2 and TMPRSS2 Variation in Savanna Monkeys (Chlorocebus\u00a0Spp.): Potential Risk for Zoonotic\/Anthroponotic\u00a0Transmission of SARS-CoV-2 and a Potential Model for Functional Studies<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Schmitt et al. found genomic evidence that several species of\u00a0<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">avanna monkey\u00a0<\/span><span data-contrast=\"auto\">(<\/span><i><span data-contrast=\"auto\">Chlorocebus<\/span><\/i><i><span data-contrast=\"auto\">\u00a0spp<\/span><\/i><i><span data-contrast=\"auto\">.<\/span><\/i><span data-contrast=\"auto\">)\u00a0<\/span><span data-contrast=\"auto\">are likely as susceptible to SARS-CoV-2 infection as humans. These findings suggest the<\/span><span data-contrast=\"auto\">y<\/span><span data-contrast=\"auto\">\u00a0may be a promising animal model for SARS-CoV-2 infection for vaccine and therapy development as well as the potential for bi-directional zoonotic transfer in savanna monkey populations. This may have further implications of epidemic control in communities with frequent human\/non-human primate interactions.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Schmitt et al. (June 23, 2020). ACE2 and TMPRSS2 Variation in Savanna Monkeys (<\/span><\/i><i><span data-contrast=\"none\">Chlorocebus<\/span><\/i><i><span data-contrast=\"none\">\u00a0Spp.): Potential Risk for Zoonotic\/<\/span><\/i><i><span data-contrast=\"none\">Anthroponotic<\/span><\/i><i><span data-contrast=\"none\">\u00a0Transmission of SARS-CoV-2 and a Potential Model for Functional Studies.\u00a0<\/span><\/i><i><span data-contrast=\"none\">PloS<\/span><\/i><i><span data-contrast=\"none\">\u00a0One.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0235106\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1371\/journal.pone.0235106<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7774\" class=\"su-post\">\n<h5 class=\"su-post-title\">Persistent Positivity and Fluctuations of SARS-CoV-2 RNA in\u00a0Clinically-Recovered\u00a0COVID-19 Patients<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Cento et al. found that 47% (235\/501) of hospitalized COVID-19 patients still tested positive at symptom resolution. Among patients who\u00a0<\/span><span data-contrast=\"auto\">were discharged<\/span><span data-contrast=\"auto\">, 14% (976\/7127) still tested positive 14<\/span><span data-contrast=\"auto\">&#8211;<\/span><span data-contrast=\"auto\">days after hospital discharge. In addition, among patients who\u00a0<\/span><span data-contrast=\"auto\">were retested<\/span><span data-contrast=\"auto\">\u00a0following their first negative RT-PCR test result,\u00a0<\/span><span data-contrast=\"auto\">9<\/span><span data-contrast=\"auto\">1<\/span><span data-contrast=\"auto\">% (196\/264) tested positive again within the first month of discharge.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Cento et al. (June 11, 2020). Persistent Positivity and Fluctuations of SARS-CoV-2 RNA in\u00a0<\/span><\/i><i><span data-contrast=\"none\">Clinically-Recovered<\/span><\/i><i><span data-contrast=\"none\">\u00a0COVID-19 Patients. Journal of Infection.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.jinf.2020.06.024\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.jinf.2020.06.024<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7772\" class=\"su-post\">\n<h5 class=\"su-post-title\">Asymptomatic SARS-CoV-2 Infection in Nursing Homes, Barcelona, Spain, April 2020<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Residents and staff at 69 nursing homes in Spain\u00a0<\/span><span data-contrast=\"auto\">were screened<\/span><span data-contrast=\"auto\">\u00a0for SARS-CoV-2 between April 10-24, 2020<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">Twenty-four percent<\/span><span data-contrast=\"auto\">\u00a0(768\/3214) of residents and 15% (403\/2655)\u00a0<\/span><span data-contrast=\"auto\">of\u00a0<\/span><span data-contrast=\"auto\">staff tested positive. Among those who tested positive, 70% of residents and 56% of staff were asymptomatic at the time of testing.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Borras<\/span><\/i><i><span data-contrast=\"none\">-Bermejo et al. (June 23, 2020). Asymptomatic SARS-CoV-2 Infection in Nursing Homes, Barcelona, Spain, April 2020. Emerging Infectious Diseases.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.3201\/eid2609.202603\"><span data-contrast=\"none\">https:\/\/doi.org\/10.3201\/eid2609.202603<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7770\" class=\"su-post\">\n<h5 class=\"su-post-title\">Using Influenza Surveillance Networks to Estimate State-Specific Prevalence of SARS-CoV-2 in the United States<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-contrast=\"auto\">Silverman\u00a0<\/span><span data-contrast=\"auto\">et<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">al<\/span><span data-contrast=\"auto\">\u00a0use outpatient surveillance data for<\/span><span data-contrast=\"auto\">\u00a0influenza-like illness to estimate the prevalence of SARS-CoV-2 in\u00a0<\/span><span data-contrast=\"auto\">the\u00a0<\/span><span data-contrast=\"auto\">US. Assuming\u00a0<\/span><span data-contrast=\"auto\">that one third<\/span><span data-contrast=\"auto\">\u00a0of all people infected with SARS-CoV-2 sought care, the authors estimated that a surge of influenza-like illness corresponded to over 8.7 million new SARS-CoV-2 infections across the US between March 8-28, 2020<\/span><span data-contrast=\"auto\">, which is substantially more\u00a0<\/span><span data-contrast=\"auto\">than the number of infections that\u00a0<\/span><span data-contrast=\"auto\">were detected<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0The authors also estimated that the early US epidemic doubled in size at least every 4 days, and that over 80%\u00a0<\/span><span data-contrast=\"auto\">of\u00a0<\/span><span data-contrast=\"auto\">cases were undetected.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Silverman et al. (June 22, 2020). Using Influenza Surveillance Networks to Estimate State-Specific Prevalence of SARS-CoV-2 in the United States. Science Translational Medicine.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1126\/scitranslmed.abc1126\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1126\/scitranslmed.abc1126<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7768\" class=\"su-post\">\n<h5 class=\"su-post-title\">COVID-19 Outbreak Among College Students After a Spring Break Trip to Mexico \u2014 Austin, Texas, March 26\u2013April 5, 2020<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">T<\/span><span data-contrast=\"auto\">ransmission of SARS-CoV-2 during and after a college spring break trip\u00a0<\/span><span data-contrast=\"auto\">to\u00a0<\/span><span data-contrast=\"auto\">Cabo San Lucas, Mexico\u00a0<\/span><span data-contrast=\"auto\">(March 14\u201319) led to 64 cases, including 60<\/span><span data-contrast=\"auto\">\u00a0cases<\/span><span data-contrast=\"auto\">\u00a0among 183 vacation travelers, one among 13 household contacts, and three among 35 community contacts.\u00a0<\/span><span data-contrast=\"auto\">A<\/span><span data-contrast=\"auto\">pproximately one-<\/span><span data-contrast=\"auto\">fifth of\u00a0<\/span><span data-contrast=\"auto\">those who tested positive\u00a0<\/span><span data-contrast=\"auto\">were asymptomatic\u00a0<\/span><span data-contrast=\"auto\">at the time of testing.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Prompt epidemiologic investigation, with effective contact tracing and cooperation between a university and a public health department, contributed to\u00a0<\/span><span data-contrast=\"auto\">the control of the\u00a0<\/span><span data-contrast=\"auto\">outbreak.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Lewis et al. (June 24, 2020). COVID-19 Outbreak Among College Students After a Spring Break Trip to Mexico \u2014 Austin, Texas, March 26\u2013April 5, 2020. MMWR. Morbidity and Mortality Weekly Report.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.15585\/mmwr.mm6926e1\"><span data-contrast=\"none\">https:\/\/doi.org\/10.15585\/mmwr.mm6926e1<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Testing and Treatment<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7784\" class=\"su-post\">\n<h5 class=\"su-post-title\">Clinical Predictors of Donor Antibody Titer and Correlation with Recipient Antibody Response in a COVID-19 Convalescent Plasma Clinical Trial<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"1\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Madariaga<\/span><span data-contrast=\"auto\">\u00a0et al. investigated predictors of convalescent antibody production in 103\u00a0<\/span><span data-contrast=\"auto\">convalescent plasma donors<\/span><span data-contrast=\"auto\">\u00a0with\u00a0<\/span><span data-contrast=\"auto\">confirmed COVID-19<\/span><span data-contrast=\"auto\">\u00a0disease<\/span><span data-contrast=\"auto\">\u00a0and found that age, fever, absence of\u00a0<\/span><span data-contrast=\"auto\">myalgia,<\/span><span data-contrast=\"auto\">\u00a0fatigue,\u00a0<\/span><span data-contrast=\"auto\">AB\u00a0<\/span><span data-contrast=\"auto\">blood type<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0and hospitalization were all associated with higher convalescent antibody titer to COVID-19.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Most (8\/10) convalescent plasma recipients had significant increases in antibody levels post-transfusion<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">A<\/span><span data-contrast=\"auto\">nti-receptor binding domain antibody titer increased on average 31% per day during the first three days post-transfusion (p=0.01) and anti-spike antibody titer increased by 40% (p<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">=0.02). Eight recipients\u00a0<\/span><span data-contrast=\"auto\">were discharged<\/span><span data-contrast=\"auto\">, one remained hospitalized, and one died.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Madariaga<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al. (June 23, 2020). Clinical Predictors of Donor Antibody Titer and Correlation with Recipient Antibody Response in a COVID-19 Convalescent Plasma Clinical Trial.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print downloaded June 24 from<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.06.21.20132944\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.06.21.20132944<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7782\" class=\"su-post\">\n<h5 class=\"su-post-title\">Impact of Glucocorticoid Treatment\u00a0In\u00a0SARS-CoV-2 Infection Mortality: A Retrospective Controlled Cohort Study<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">In a retrospective analysis of 463 hospitalized COVID-19 patients, Fernandez-Cruz et al. found that in-hospital mortality was lower among patients treated with steroids (14%; 55\/396) than in those who were not (24%; 16\/67). Glucocorticoids steroid treatment was associated with a 42% reduction in mortality.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Fern\u00e1ndez<\/span><\/i><i><span data-contrast=\"none\">\u00a0Cruz et al. (June 22, 2020).\u00a0<\/span><\/i><i><span data-contrast=\"none\">Impact of Glucocorticoid Treatment\u00a0<\/span><\/i><i><span data-contrast=\"none\">In<\/span><\/i><i><span data-contrast=\"none\">\u00a0SARS-CoV-2 Infection Mortality: A Retrospective Controlled Cohort Study.<\/span><\/i><i><span data-contrast=\"none\">\u00a0Antimicrobial Agents and Chemotherapy.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1128\/AAC.01168-20\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1128\/AAC.01168-20<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7780\" class=\"su-post\">\n<h5 class=\"su-post-title\">Simulation of Pool Testing to Identify Patients\u00a0With\u00a0Coronavirus Disease 2019 Under Conditions of Limited Test Availability<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Using mathematical simulations,\u00a0<\/span><span data-contrast=\"auto\">Cherif<\/span><span data-contrast=\"auto\">\u00a0et al. suggest that a pool<\/span><span data-contrast=\"auto\">ed<\/span><span data-contrast=\"auto\">\u00a0testing strategy<\/span><span data-contrast=\"auto\">\u00a0(<\/span><span data-contrast=\"auto\">testing a pooled sample from several patients<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">\u00a0was more\u00a0<\/span><span data-contrast=\"auto\">efficient<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">than individual testing when prevalence was below 30%. The optimal pool size\u00a0<\/span><span data-contrast=\"auto\">was inversely related<\/span><span data-contrast=\"auto\">\u00a0to the prevalence of SARS-CoV-2 positive specimens and the sensitivity of the assay.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Cherif<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al. (June 23, 2020). Simulation of Pool Testing to Identify Patients\u00a0<\/span><\/i><i><span data-contrast=\"none\">With<\/span><\/i><i><span data-contrast=\"none\">\u00a0Coronavirus Disease 2019 Under Conditions of Limited Test Availability. JAMA Network Open.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.13075\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.13075<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7778\" class=\"su-post\">\n<h5 class=\"su-post-title\">Development and Potential Usefulness of the COVID-19 Ag\u00a0Respi-Strip Diagnostic Assay in a Pandemic Context<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Respi<\/span><span data-contrast=\"auto\">-Strip is an\u00a0<\/span><span data-contrast=\"auto\">immunochromatographic<\/span><span data-contrast=\"auto\">\u00a0(ICT) assay for the rapid detection of SARS-CoV-2 antigen on nasopharyngeal specimen<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">\u00a0that<\/span><span data-contrast=\"auto\">\u00a0provides diagnostic results within 15 minutes. When validated against RT-PCR tests (<\/span><span data-contrast=\"auto\">n<\/span><span data-contrast=\"auto\">=328), the assay had low sensitivity (57.6%) and high specificity (99.5%).<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Mertens<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al. (May 8, 2020). Development and Potential Usefulness of the COVID-19 Ag\u00a0<\/span><\/i><i><span data-contrast=\"none\">Respi<\/span><\/i><i><span data-contrast=\"none\">-Strip Diagnostic Assay in a Pandemic Context. Frontiers in Medicine.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.3389\/fmed.2020.00225\"><span data-contrast=\"none\">https:\/\/doi.org\/10.3389\/fmed.2020.00225<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Clinical Characteristics and Health Care Setting<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7786\" class=\"su-post\">\n<h5 class=\"su-post-title\">Risk Factors for 2019 Novel Coronavirus Disease (COVID-19) Patients Progressing to Critical Illness: A Systematic Review and Meta-Analysis<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">In a meta-analysis of 20 studies, Xu et al. found that gender, advanced age, higher BMI, and comorbidities (diabetes, hypertension, cardiovascular disease, and chronic obstructive pulmonary disease) are associated with higher risk for developing severe COVID-19 disease. In addition, several laboratory measures were also associated with severe disease, notably: high white blood cell count, low lymphocyte count, low albumin, high ALT\/AST, LDH, C-reactive protein, and\u00a0<\/span><span data-contrast=\"auto\">creatine<\/span><span data-contrast=\"auto\">\u00a0kinase.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Xu et al. (June 23, 2020). Risk Factors for 2019 Novel Coronavirus Disease (COVID-19) Patients Progressing to Critical Illness: A Systematic Review and Meta-Analysis. Aging.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.18632\/aging.103383\"><span data-contrast=\"none\">https:\/\/doi.org\/10.18632\/aging.103383<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span style=\"font-weight: 400\">Modeling and Prediction<\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-7790\" class=\"su-post\">\n<h5 class=\"su-post-title\">COVID-19 Lockdown: If, When, and How<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2\" data-aria-level=\"1\"><i><span data-contrast=\"auto\">[pre-print, not peer reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Moyorga<\/span><span data-contrast=\"auto\">\u00a0et al. evaluated the impact of different timings and lengths of lockdown periods under scenarios<\/span><span data-contrast=\"auto\">\u00a0using different values of R<\/span><span data-contrast=\"auto\">0<\/span><span data-contrast=\"auto\">, the basic reproductive number for SARS-CoV-2<\/span><span data-contrast=\"auto\">. They found that the timing for the lockdown has\u00a0<\/span><span data-contrast=\"auto\">a large effect on\u00a0<\/span><span data-contrast=\"auto\">ICU usage and fatalities. As R<\/span><span data-contrast=\"auto\">0<\/span><span data-contrast=\"auto\">\u00a0increases,\u00a0<\/span><span data-contrast=\"auto\">an\u00a0<\/span><span data-contrast=\"auto\">earlier lockdown<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">is\u00a0<\/span><span data-contrast=\"auto\">needed<\/span><span data-contrast=\"auto\">\u00a0to control the outbreak<\/span><span data-contrast=\"auto\">, while in lower R<\/span><span data-contrast=\"auto\">0<\/span><span data-contrast=\"auto\">\u00a0scenarios later lockdowns\u00a0<\/span><span data-contrast=\"auto\">are still\u00a0<\/span><span data-contrast=\"auto\">effective.\u00a0<\/span><span data-contrast=\"auto\">A l<\/span><span data-contrast=\"auto\">ockdown<\/span><span data-contrast=\"auto\">\u00a0of<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">&lt;15 days long had a negligible effect in\u00a0<\/span><span data-contrast=\"auto\">reducing the impact of SARS-CoV-2 on\u00a0<\/span><span data-contrast=\"auto\">the\u00a0<\/span><span data-contrast=\"auto\">healthcare system. However, lockdowns &gt;45 days had diminishing returns on their effect of reducing ICU usage and fatalities.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Mayorga<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al. (June 23, 2020). COVID-19 Lockdown: If, When, and How.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print downloaded June 24 from<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.06.20.20136325\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.06.20.20136325<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-7788\" class=\"su-post\">\n<h5 class=\"su-post-title\">The End of Social Confinement and COVID-19 Re-Emergence Risk<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Results from a stochastic model of SARS-CoV-2 transmission developed by Lopez et al. suggest that lockdowns should remain in place for a minimum of 60 days, followed by a gradual reintroduction of the workforce. The authors found that social distancing, face masks, gloves and other individual protection measures h<\/span><span data-contrast=\"auto\">ave<\/span><span data-contrast=\"auto\">\u00a0a massive impact in reducing the current peak of active cases, but that waning adherence to these interventions over time could result in a larger second epidemic wave.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">L\u00f3pez<\/span><\/i><i><span data-contrast=\"none\">\u00a0and\u00a0<\/span><\/i><i><span data-contrast=\"none\">Rod\u00f3<\/span><\/i><i><span data-contrast=\"none\">. (June 22, 2020). The End of Social Confinement and COVID-19 Re-Emergence Risk. Nature Human\u00a0<\/span><\/i><i><span data-contrast=\"none\">Behaviour<\/span><\/i><i><span data-contrast=\"none\">.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1038\/s41562-020-0908-8\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1038\/s41562-020-0908-8<\/span><\/a><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<h3><strong>Other Resources and Commentaries<\/strong><\/h3>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"1\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1126\/science.abc6952\"><span data-contrast=\"none\">A Neutralizing Human Antibody Binds to the N-Terminal Domain of the Spike Protein of SARS-CoV-2<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Science (June 22)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1101\/2020.06.22.165464\"><span data-contrast=\"none\">Accommodating Individual Travel History Global Mobility and\u00a0<\/span><span data-contrast=\"none\">Unsampled<\/span><span data-contrast=\"none\">\u00a0Diversity in\u00a0<\/span><span data-contrast=\"none\">Phylogeography<\/span><span data-contrast=\"none\">:<\/span><span data-contrast=\"none\">\u00a0a SARS-CoV-2 Case Study<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0<\/span><span data-contrast=\"auto\">Biorxiv<\/span><span data-contrast=\"auto\">\u00a0(June 23)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"3\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1001\/jama.2020.8484\"><span data-contrast=\"none\">After COVID-19: Thinking Differently About Running the Health Care System<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 JAMA (June 23)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"1\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.3390\/pathogens9060480\"><span data-contrast=\"none\">Are Animals a Neglected Transmission Route of SARS-CoV-2?<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Pathogens (June 18)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.3389\/fmicb.2020.01020\"><span data-contrast=\"none\">The Novel Coronavirus COVID-19 Outbreak: Global Implications for Antimicrobial Resistance<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Frontiers in Microbiology\u00a0<\/span><span data-contrast=\"auto\">(<\/span><span data-contrast=\"auto\">May 13<\/span><span data-contrast=\"auto\">)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"3\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/j.jacbts.2020.05.002\"><span data-contrast=\"none\">The National Institute of Allergy and Infectious Diseases Decision to Stop the Adaptive COVID-19 Trial: On Solid Ethical and Scientific Grounds<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 JACC Basic to Translational Science (<\/span><span data-contrast=\"auto\">May 26<\/span><span data-contrast=\"auto\">)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"4\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1136\/bmj.m2333\"><span data-contrast=\"none\">Covid-19 Is Threatening the Survival of US Primary Care<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 BMJ (June 22)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"5\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.3390\/ijerph17124392\"><span data-contrast=\"none\">Potential Years of Life Lost Due to COVID-19 in the United States, Italy, and Germany: An Old Formula with Newer Ideas<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 International Journal of Environmental Research and Public Health (June 18)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>A college spring break trip resulted in SARS-CoV-2 infection in 60 (28%) college-aged travelers and their contacts included in the outbreak investigation, one-fifth of whom were asymptomatic at the time of testing.<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/24\/the-end-of-social-confinement-and-covid-19-re-emergence-risk\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":7792,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[5],"tags":[],"topic":[],"class_list":["post-7766","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19-literature-situation-report"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7766","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7766"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7766\/revisions"}],"predecessor-version":[{"id":7793,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7766\/revisions\/7793"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media\/7792"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7766"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7766"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7766"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7766"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}