{"id":7804,"date":"2020-06-25T13:01:21","date_gmt":"2020-06-25T20:01:21","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7804"},"modified":"2021-03-26T13:02:09","modified_gmt":"2021-03-26T20:02:09","slug":"effect-of-colchicine-vs-standard-care-on-cardiac-and-inflammatory-biomarkers-and-clinical-outcomes-in-patients-hospitalized-with-coronavirus-disease-2019","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/25\/effect-of-colchicine-vs-standard-care-on-cardiac-and-inflammatory-biomarkers-and-clinical-outcomes-in-patients-hospitalized-with-coronavirus-disease-2019\/","title":{"rendered":"Effect of Colchicine vs Standard Care on Cardiac and Inflammatory Biomarkers and Clinical Outcomes in Patients Hospitalized\u00a0With\u00a0Coronavirus Disease 2019"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">A randomized trial (n=105) evaluat<\/span><span data-contrast=\"auto\">ed<\/span><span data-contrast=\"auto\">\u00a0the effect of treatment with\u00a0<\/span><span data-contrast=\"auto\">the anti-inflammatory agent\u00a0<\/span><span data-contrast=\"auto\">colchicine\u00a0<\/span><span data-contrast=\"auto\">in patients with COVID-19. T<\/span><span data-contrast=\"auto\">he group receiving colchicine had a lower rate of clinical deterioration (defined as a 2-grade increase on a 7-grade clinical status scale) (OR = 0.11, 95% CI: 0.01-0.96).<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">T<\/span><span data-contrast=\"auto\">here\u00a0<\/span><span data-contrast=\"auto\">were no significant differences between treatment and control groups for\u00a0<\/span><span data-contrast=\"auto\">cardiac<\/span><span data-contrast=\"auto\">\u00a0outcomes<\/span><span data-contrast=\"auto\">\u00a0and inflammatory biomarkers<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Deftereos\u00a0et al. (June 24, 2020). Effect of Colchicine vs Standard Care on Cardiac and Inflammatory Biomarkers and Clinical Outcomes in Patients Hospitalized\u00a0With\u00a0Coronavirus Disease 2019. JAMA Network Open.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.13136\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.13136<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A randomized trial (n=105) evaluated\u00a0the effect of treatment with\u00a0the anti-inflammatory agent\u00a0colchicine\u00a0in patients with COVID-19. The group receiving colchicine had a lower rate of clinical deterioration (defined as a 2-grade increase on a 7-grade clinical status scale) (OR = 0.11, 95% CI: 0.01-0.96).\u00a0 \u00a0There\u00a0were no significant differences between treatment and control groups for\u00a0cardiac\u00a0outcomes\u00a0and inflammatory biomarkers.\u00a0 Deftereos\u00a0et&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/25\/effect-of-colchicine-vs-standard-care-on-cardiac-and-inflammatory-biomarkers-and-clinical-outcomes-in-patients-hospitalized-with-coronavirus-disease-2019\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-7804","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7804","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7804"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7804\/revisions"}],"predecessor-version":[{"id":7805,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7804\/revisions\/7805"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7804"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7804"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7804"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7804"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}