{"id":7812,"date":"2020-06-25T13:06:09","date_gmt":"2020-06-25T20:06:09","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7812"},"modified":"2021-03-26T13:06:51","modified_gmt":"2021-03-26T20:06:51","slug":"a-mathematical-model-reveals-the-influence-of-population-heterogeneity-on-herd-immunity-to-sars-cov-2","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/25\/a-mathematical-model-reveals-the-influence-of-population-heterogeneity-on-herd-immunity-to-sars-cov-2\/","title":{"rendered":"A Mathematical Model Reveals the Influence of Population Heterogeneity on Herd Immunity to SARS-CoV-2"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">A modeling study found\u00a0<\/span><span data-contrast=\"auto\">that heterogeneity\u00a0<\/span><span data-contrast=\"auto\">in contact rates\u00a0<\/span><span data-contrast=\"auto\">among<\/span><span data-contrast=\"auto\">\u00a0population<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">groups<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">can significantly\u00a0<\/span><span data-contrast=\"auto\">affect<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">the overall level of\u00a0<\/span><span data-contrast=\"auto\">disease-induced immunity\u00a0<\/span><span data-contrast=\"auto\">to SARS-CoV-2 that develops in the population<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Britton\u00a0<\/span><span data-contrast=\"auto\">e<\/span><span data-contrast=\"auto\">t al.<\/span><span data-contrast=\"auto\">\u00a0estimate that if R<\/span><span data-contrast=\"auto\">0<\/span><span data-contrast=\"auto\">\u00a0= 2.5 in an age-structured community with mixing rates fitted to social activity<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0then the disease-induced herd immunity level can be around 43%, which is substantially less than the classical herd immunity level of 60% obtained through homogeneous immunization of the population.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Britton et al. (June 23, 2020). A Mathematical Model Reveals the Influence of Population Heterogeneity on Herd Immunity to SARS-CoV-2. Science.<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><a href=\"https:\/\/science.sciencemag.org\/content\/early\/2020\/06\/22\/science.abc6810\"><span data-contrast=\"none\">https:\/\/science.sciencemag.org\/content\/early\/2020\/06\/22\/science.abc6810<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A modeling study found\u00a0that heterogeneity\u00a0in contact rates\u00a0among\u00a0population\u00a0groups\u00a0can significantly\u00a0affect\u00a0the overall level of\u00a0disease-induced immunity\u00a0to SARS-CoV-2 that develops in the population.\u00a0Britton\u00a0et al.\u00a0estimate that if R0\u00a0= 2.5 in an age-structured community with mixing rates fitted to social activity,\u00a0then the disease-induced herd immunity level can be around 43%, which is substantially less than the classical herd immunity level of 60%&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/06\/25\/a-mathematical-model-reveals-the-influence-of-population-heterogeneity-on-herd-immunity-to-sars-cov-2\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[23],"class_list":["post-7812","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-modeling-and-prediction"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7812","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7812"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7812\/revisions"}],"predecessor-version":[{"id":7813,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7812\/revisions\/7813"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7812"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7812"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7812"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7812"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}